Category: immunology

“The first author assumes all responsibility:” Malaria vaccine article retracted for image manipulation

InfectAndImmunAuthors of a 2012 article in Infection and Immunity investigating a malaria vaccine strategy are retracting it because it “contains several images that do not accurately reflect the experimental data.”

The paper, “Fine Specificity of Plasmodium vivax Duffy Binding Protein Binding Engagement of the Duffy Antigen on Human Erythrocytes,” has been cited 9 times, according to Thomson Scientific’s Web of Knowledge.

The retraction notice places the blame for the image shenanigans squarely on the first author, Asim Siddiqui, who is currently listed on LinkedIn as a faculty member at the College of Applied Medicine at King Saud University in Saudi Arabia.

Here’s the notice: Continue reading “The first author assumes all responsibility:” Malaria vaccine article retracted for image manipulation

Two more retractions bring lab break-in biochemist up to eleven

bbrcKarel Bezouška, the Czech biochemist who was caught on hidden camera breaking into a lab fridge to fake results, has turned it up to eleven with two new retractions.

Both retractions appeared in Biochemical and Biophysical Research Communications, one in October 2014 and one in January 2015.  His story began two decades ago in 1994, when he published a paper in Nature that couldn’t be reproduced, and was eventually retracted in 2013.

The best part of the story, of course, is that when his university was attempting to recreate his experiments, Bezouška broke into a lab fridge to tamper with the experiments. Unbeknownst to him, he was caught on hidden camera.  Continue reading Two more retractions bring lab break-in biochemist up to eleven

Leukemia paper retracted for plagiarism — 18 years later

BTER_116_1_cvr_spine.p65Nearly two decades after a Polish researcher plagiarized the work of a Turkish team, her theft has been exposed and the paper retracted.

According to an article in Polish-language paper Gazeta Wyborcza, Jolanta Rzymowska of the Medical University of Lublin was the subject of two disciplinary hearings, the first in February 2014, following the discovery of her plagiarism by well-known Polish fraud hunter Marek Wronski. It was determined that her 1996 paper contained word-for-word text from a paper by a team at the University of Ankara.

Ultimately, Rzymowska was given an official reprimand, rather than any harsher disciplinary action, because she copied descriptions rather than results. From a Google translation of the article: Continue reading Leukemia paper retracted for plagiarism — 18 years later

Downstream effects: Comment on retracted narcolepsy paper retracted

stmcoverThe recent retraction of a paper in Science Translational Medicine reporting “one of the biggest things to happen” in narcolepsy research has claimed a bystander: A letter that commented on the no-longer-landmark article.

The authors of the letter are with GlaxoSmithKline’s vaccine division. Here’s the new notice: Continue reading Downstream effects: Comment on retracted narcolepsy paper retracted

Researcher who broke into lab up to nine retractions

bichaw_v053i036.inddKarel Bezouška, a researcher who broke into a lab refrigerator to tamper with an investigation into his work, has nine retractions.

Here’s the retraction notice in Biochemistry for 2010’s “Cooperation between Subunits Is Essential for High-Affinity Binding of N-Acetyl-d-hexosamines to Dimeric Soluble and Dimeric Cellular Forms of Human CD69:” Continue reading Researcher who broke into lab up to nine retractions

Seventh retraction appears for author who tampered with investigation

bioorganicsKarel Bezouška, who tried tampering with an investigation into his work by breaking into a lab refrigerator, has had a seventh paper retracted.

Here’s the notice for “Carboxylated calixarenes bind strongly to CD69 and protect CD69+ killer cells from suicidal cell death induced by tumor cell surface ligands,” which was first published in Bioorganic & Medicinal Chemistry in 2010: Continue reading Seventh retraction appears for author who tampered with investigation

Third retraction for Karel Bezouška, of lab break-in fame

bichaw_v052i049.inddWe’ve found a third retraction for Karel Bezouška, the Czech scientist, who, as we reported this summer, broke into a lab in an attempt to tamper with experiments trying to replicate his own falsified data.

The article, “Molecular Characterization of Binding of Calcium and Carbohydrates by an Early Activation Antigen of Lymphocytes CD69,” had appeared in 2003 in Biochemistry. and has been cited 29 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction notice: Continue reading Third retraction for Karel Bezouška, of lab break-in fame

PNAS retraction notice reveals name of Leiden University researcher fired for data manipulation

pnas 1113In August, we reported on a case in which a researcher had been fired from Leiden University in the Netherlands for fraud. The university said there would be two retractions, but did not name the researcher in question. At the same time, however, there were clues in the university’s report that suggested it could only be one person, the lead author of a 2010 study in the Proceedings of the National Academy of Sciences (PNAS) that was to be retracted.

That notice has now appeared, and confirms that the fired employee was Annemie Schuerwegh, as a number of our comments surmised. Here’s the notice: Continue reading PNAS retraction notice reveals name of Leiden University researcher fired for data manipulation

Authors retract two papers on Remicade following legal battles

april_2009_ar_coverA group of Belgian researchers has retracted two decade-old papers in Arthritis & Rheumatism following an investigation and court case.

The papers involved the use of the drug infliximab — sold by Johnson & Johnson as Remicade  — to treat Sjögren’s syndrome, an auto-immune condition marked by the destruction of exocrine glands that secrete saliva and tears.

Infliximab is not approved for Sjögren’s. Although the two now-retracted studies suggested that it might be helpful, subsequent data did not support those findings.

Neither, apparently, did the studies themselves. Here’s the retraction notice (it’s a PDF): Continue reading Authors retract two papers on Remicade following legal battles

University of Minnesota swine flu researcher under investigation for alleged misconduct

goyal
Sagar Goyal, via University of Minnesota

In late December, we reported on the retraction of a 2010 research letter in Emerging Infectious Diseases looking at the genetics of swine flu.

The notice in the journal, a CDC publication, indicated that the conclusions were in error, although it didn’t really say much more:

To the Editor: We would like to retract the letter entitled “Triple Reassortant Swine Influenza A (H3N2) Virus in Waterfowl,” which was published the April 2010 issue of Emerging Infectious Diseases (1). The nucleoprotein gene sequences from the viruses reported in that letter are very closely related to those from the earliest detected triple reassortant swine influenza viruses [CY095676 A/sw/Texas/4199–2/1998(H3N2)]. Although these viruses could have acquired a swine-origin segment, the branch lengths are quite short for 9 years of evolution. Therefore, we have withdrawn these 4 isolates from GenBank and subsequently retract this letter.

As it happens, there was more to the story.

Continue reading University of Minnesota swine flu researcher under investigation for alleged misconduct