Seventh retraction appears for author who tampered with investigation

bioorganicsKarel Bezouška, who tried tampering with an investigation into his work by breaking into a lab refrigerator, has had a seventh paper retracted.

Here’s the notice for “Carboxylated calixarenes bind strongly to CD69 and protect CD69+ killer cells from suicidal cell death induced by tumor cell surface ligands,” which was first published in Bioorganic & Medicinal Chemistry in 2010:

This article has been retracted: please see Elsevier Policy on Article Withdrawal (

This article has been retracted at the request of the Authors.

The above paper describes synthesis of a series of substituted calixarenes, which were fully characterized and their binding to the human receptor CD69 and respective interactions. Unfortunately, we have learned recently that the author responsible for the immunological experiments—Prof. Karel Bezouška—has been fabricating the results and most plausibly also manipulating with experimental material in collaborating laboratories. Based on the findings of the joint ethical committee of the Institute of Microbiology, Acad. Sci. of the Czech Republic, and Charles University in Prague we consider all the data on the binding of ligands to the CD69 receptor erroneous and, therefore, we retract the above publication. We would like to apologize to all affected parties.

The paper has been cited 13 times, according to Thomson Scientific’s Web of Knowledge.

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