Category: united states

U Colorado revokes PhD of former “golden boy”

university-of-colorado-denver-300x58In a rare move, the University of Colorado has revoked the PhD of a former student in a pharmaceutical research lab, following an investigation that raised concerns about the integrity of his work.

According to The Denver Post, Rajendra Kadam’s degree has been revoked by the University of Colorado Board of Regents.

Last year, an investigation by the University of Colorado Denver into Kadam’s research recommended retracting 10 papers. As we reported at the time, the report flagged eight additional papers co-authored by Kadam whose data could not be validated, raising “concerns as to the scientific validity and integrity” of the material.

Last month, a University of Colorado Denver spokesperson told us Kadam was no longer affiliated with the university; today, Ken McConnellogue, the vice president for communication, confirmed that his degree has now been revoked entirely.

McConnellogue acknowledged that it was a strong move: Continue reading U Colorado revokes PhD of former “golden boy”

Biologist loses second paper — again, for unvalidated figures

Cellular SignallingA researcher at Case Western Reserve University in Ohio has retracted a second paper after a review found the figures didn’t match the original data.  

Last year, we reported on a previous retraction of a paper co-authored by biologist Alan Levine in Inflammatory Bowel Diseases, which was pulled for the exact same reason; even the retraction notices use similar language. The first author on both papers is Debasmita Mandal, also listed at Case Western Reserve University.

Here’s the retraction notice for “REDOX regulation of IL-13 signaling in intestinal epithelial cells: usage of alternate pathways mediates distinct gene expression patterns,” published by Cellular Signalling: Continue reading Biologist loses second paper — again, for unvalidated figures

Author objects to retraction of heart study, implies industry played role

JACC

The Journal of the American College of Cardiology (JACC) has retracted a recently published paper that questioned the effectiveness of a treatment for irregular heartbeat, against the last author’s wishes. 

Andrea Natale, the study’s last and corresponding author and Executive Medical Director of Texas Cardiac Arrhythmia at Austin, took to social media today to express his frustration in the retraction of the July paper, which showed electrical rotors were less effective at fixing irregular heartbeat than other treatments. On Twitter, Natale implied industry played a role in its demise.

However, according to the retraction notice, the paper was felled by problems with randomization; Natale has admitted that some patients were removed from the analysis after one center included them incorrectly.

Here’s the retraction notice for “Impact of Rotor Ablation in Nonparoxysmal Atrial Fibrillation Patients Results From the Randomized OASIS Trial:” Continue reading Author objects to retraction of heart study, implies industry played role

Scientists investigated for misconduct lose appeal in suit against Harvard. Lawyers explain what it means.

Paul S. Thaler
Paul S. Thaler
Richard Goldstein
Richard Goldstein

Retraction Watch readers may recall the case of Piero Anversa and Annarosa Leri, both formerly of Harvard and the Brigham & Women’s Hospital in Boston. The pair — which has had their work subjected to a retraction, expression of concern, and correction — sued their former employers in 2014 for costing them job offers after the institutions notified journals, triggering notices. A judge dismissed the case a year ago, saying that Anversa and Leri had to try other administrative remedies before bringing suit.

But Anversa and Leri appealed, and last week, a court denied that appeal. (See the judge’s decision — which begins by quoting Ecclesiastes and includes the delicious word “gallimaufry” — here.) We spoke by email to two attorneys — Richard Goldstein, who represented the scientist in Bois v. HHS, the first case to overturn a funding ban by the Office of Research Integrity (ORI), and Paul Thaler, who has represented scientists involved in misconduct proceedings for more than 25 years — about the case, and what it could mean for similar lawsuits.

Retraction Watch: The decision seems to stop Anversa and Leri from continuing their suit against Harvard and the Brigham, but also acknowledges some of the scientists’ concerns as legitimate. How would you summarize the findings and their implications? Continue reading Scientists investigated for misconduct lose appeal in suit against Harvard. Lawyers explain what it means.

Cancer researcher logs 5th retraction

Journal of Mammary Gland Biology and NeoplasiaA cancer researcher has added a fifth retraction to his name — but the notice doesn’t mention any problems with the paper itself. 

Rather, the Journal of Mammary Gland Biology and Neoplasia decided to retract the paper because it referenced other papers that had been retracted as a result of data manipulation.

The notice doesn’t specify which references were problematic, but the list includes three papers that are now retracted; all three include Scott Valastyan (the sole author of the newly retracted paper) as first author, and two list Robert Weinberg, his former supervisor and prominent cancer researcher, as last author.

Continue reading Cancer researcher logs 5th retraction

Retraction appears for group whose former member was sanctioned by ORI

Journal of Biological ChemistryResearchers whose former colleague was recently reprimanded by the U.S. Office of Research Integrity (ORI) have retracted a biology paper for duplication.

The retraction includes some familiar names: The last author Steven Grant, senior author of the newly retracted study, is also the last author of 11 papers flagged in a report by the ORI in December, 2015. That report focused on Girija Dasmahapatra, a co-author of the 11 studies who was also based at at Virginia Commonwealth University (VCU). Dasmahapatra left VCU in 2015, and is not listed on the latest retraction.

The retracted paper, published in The Journal of Biological Chemistry (JBC), was also co-authored by Paul Dent, a biochemist at the VCU, who we mentioned last year when he offered to retract another paper in Molecular Pharmacology after concerns arose on PubPeer. The journal has instead issued a lengthy correction (what we call a “mega-correction”).

A VCU spokesperson told us:
Continue reading Retraction appears for group whose former member was sanctioned by ORI

Embezzlement, 15 retractions, and a whistleblower could add up to trouble for Duke

scienceRetraction Watch readers may recall the case of Erin Potts-Kant, who pled guilty to embezzling funds from a lab, and now has 15 retractions, and Michael Foster, both formerly of Duke. You may also remember that we’ve featured discussions of the False Claims Act, which some attorneys are trying to use to expose wrongdoing — and earn large settlements for whistleblowers in the process.

It turns out those two threads are intertwined, as we learned only last month when a federal court case against Potts-Kant, Foster, and Duke was unsealed last month. (False Claims Act cases are frequently sealed when initially filed, with big penalties for anyone — including the attorneys — who talk about them, which is why we didn’t know of this link before.) In today’s Science, as part of our new partnership, we tell the story in a lot more detail, and describe the potential ramifications for Duke and other universities.

The whistleblower in the Duke case is named Continue reading Embezzlement, 15 retractions, and a whistleblower could add up to trouble for Duke

Professor forced to retire after threatening co-author

jialalI-bio
Ishwarlal “Kenny” Jialal

As the University of California Davis is reeling from the resignation of Chancellor Linda Katehi over alleged ethical violations, we’ve learned of more drama at the school: The fallout from a single retraction back in 2012 pushed one UC Davis professor into early retirement this summer without professor emeritus status.

What’s more, a UC Davis committee had recommended that former professor Ishwarlal “Kenny” Jialal retire early but maintain his professor emeritus status, and Katehi overruled that decision, deciding to strip Jialal of any future emeritus status.

Here’s the story: Jialal was found innocent of any research misconduct after Nutrition Reviews journal editors found portions of a 2008 review paper contained writing from the Linus Pauling Institute website, according to an internal investigation. However, after the first author — former postdoc Uma Singh, now an adjunct professor at Valencia College in Orlando — admitted to plagiarizing a passage, the investigation found Jialal sent her threatening emails in reaction to the perceived smear of the retraction on his reputation.

For instance, Continue reading Professor forced to retire after threatening co-author

Author lifts from one paper in two different articles. Why does one journal retract, while the other corrects?

circ resAre there instances when similarities between papers should be fixed by a correction, rather than a retraction?

We’re asking ourselves that question after seeing two journals take very different approaches to a somewhat similar situation. Last year, Frontiers in Physiology retracted a paper by Anastasios Lymperopoulos at Nova Southeastern University in Florida because of an “an unacceptable level of similarity” to a 2009 review article by different authors. But more recently, after Circulation Research discovered another paper co-authored by Lymperopoulos also contained similar text from the same 2009 review, it decided to correct the passages.

The last author of the Circulation Research paper told us the overlap between the two papers was less than 5%, and the journal never suggested the authors retract the paper.

Here’s the correction notice in Circulation Research:

Continue reading Author lifts from one paper in two different articles. Why does one journal retract, while the other corrects?

Former NIH postdoc doctored data

ori-logoA genetics researcher included falsified data in two published papers, according to a report by the U.S. Office of Research Integrity (ORI) released today.

At the time of the misconduct, Andrew Cullinane was a postdoctoral fellow in the Medical Genetics Branch at the National Human Genome Research Institute (NHGRI). According to his LinkedIn page, he is now an assistant professor at Howard University in Washington D.C. The university’s College of Medicine lists him as an assistant professor in the Basic Sciences/Anatomy department.

As today’s notice in the Federal Register reports, Cullinane Continue reading Former NIH postdoc doctored data