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”Definitely embarrassing:” Nobel Laureate retracts non-reproducible paper in Nature journal

A Nobel Laureate has retracted a 2016 paper in Nature Chemistry that explored the origins of life on earth, after discovering the main conclusions were not correct.  

Some researchers who study the origins of life on Earth have hypothesized that RNA evolved before DNA or proteins.  If true, RNA would have needed a way to replicate without enzymes. The Nature Chemistry paper found that a certain type of peptide — which may have existed in our early history — made it possible for RNA to copy itself.

Jack W. Szostak—a professor of chemistry and chemical biology at Harvard University in Cambridge, Mass., who shared the 2009 Nobel Prize in Physiology or Medicine with Elizabeth Blackburn and Carol Greider for their pioneering research on aging—told us he was “incredibly excited” when he “thought we had at least a partial solution to this problem,” which researchers have been working on for over 50 years.  

But in subsequent experiments, Tivoli Olsen — a member of Szostak’s lab — could not reproduce the 2016 findings. When she reviewed the experiments from the Nature Chemistry paper, she found that the team had misinterpreted the initial data: The peptide in question did not appear to provide an environment that fostered RNA replication.

The errors were “definitely embarrassing,” Szostak told us: Continue reading ”Definitely embarrassing:” Nobel Laureate retracts non-reproducible paper in Nature journal

NIH to researchers: Don’t publish in bad journals, please

The U.S. National Institutes of Health has noticed something: More of the research it’s funding is ending up in questionable journals. Recently, the agency issued a statement highlighting some qualities of these journals — aggressively soliciting submissions, failing to provide clear information about pricing — and urging researchers to avoid them. The NIH’s goal: to “help protect the credibility of papers arising from its research investment.” We asked the NIH for more information about the guide notice; a representative returned responses, asking that we attribute them to the NIH Office of Extramural Research.

Retraction Watch: What prompted the NIH to issue this guide notice? Was there an incident?

Continue reading NIH to researchers: Don’t publish in bad journals, please

New York psychiatry researcher charged with embezzlement, faces jail time

Alexander Neumeister. Source: Yale School of Medicine

A researcher specializing in post-traumatic stress disorder is facing jail time for allegedly embezzling tens of thousands of dollars of federal grant money.

Yesterday, the US Attorney’s Office for the Southern District of New York and the U.S. Department of Health and Human Services’s Office of Inspector General (OIG) announced criminal charges against Alexander Neumeister, alleging he used the grant funds on trips and meals for family and friends. As the New York Times reported last year, Neumeister was dismissed from his position at New York University (NYU); NYU shut down eight of his studies following an investigation by the U.S. Food and Drug Administration, which found evidence of lax oversight, falsified records, and inaccurate case histories. 

The U.S. Attorney has also filed a civil lawsuit against Neumeister under the False Claims Act, also for misuse of grant funding. The complaint does not specify the total amount of funds he allegedly misused.

In a statement, Acting U.S. Attorney Joon Kim said Neumeister:

Continue reading New York psychiatry researcher charged with embezzlement, faces jail time

Caught Our Notice: 1,376 words of overlap in paper by food researcher Brian Wansink

Via Wikimedia

Title: Change Their Choice! Changing Behavior Using the CAN Approach and Activism Research

What Caught Our Attention: Food researcher Brian Wansink has had a rough time lately. After researchers began scrutinizing his work, he has racked up five retractions and multiple corrections. (We’re counting one retracted paper twice, as Wansink first retracted and replaced it with a new version, then retracted the replacement.)

These notices haven’t gone unnoticed, either by us or other media outlets — BuzzFeed reported on his most recent retraction this weekend, a paper a critic discussed with us, as well. Yesterday, BuzzFeed also reported that Cornell is investigating. (It wouldn’t be the first time — in April, Cornell announced that it had found evidence of mistakes, not misconduct, in Wansink’s papers.)  Below, we present his 13th correction, for duplicated text — 1,376 words of duplicated text, to be exact.

Continue reading Caught Our Notice: 1,376 words of overlap in paper by food researcher Brian Wansink

Where’s the data? Authors can’t support figures in 2017 kidney paper

Researchers have retracted a 2017 paper exploring a novel approach to treat kidney injury, because three images were “constructed inappropriately.”

That’s about as much as we know: The retraction notice provides few details about the nature of the issue, only that the authors—most of whom work at Pennsylvania State University College of Medicine in Hershey—could not provide the original data for the recently published figures.

The paper, published in American Journal of Physiology – Renal Physiology, was retracted October 1, just over four months after appearing online in mid-May. Continue reading Where’s the data? Authors can’t support figures in 2017 kidney paper

US court issues injunction against OMICS to stop “deceptive practices”

A US government agency has won an initial court ruling against OMICS, which the government says will help stop the academic publisher’s deceptive business practices.

Today, the Federal Trade Commission (FTC) announced that it won a preliminary injunction in September in its lawsuit against Srinubabu Gedela, CEO of OMICS Group and other companies.

The lawsuit, filed in August 2016, accused the defendants — which include Gedela and OMICS Group, iMedPub, and Conference Series — of deceptive business practices related to journal publishing and scientific conferences. The FTC alleged the defendants used the names of prominent researchers to draw conference attendees, even though the researchers had not agreed to participate; misled readers about whether articles had been peer reviewed; failed to provide authors with transparent information about publishing fees prior to submission; and presented misleading “impact factors” for journals.

On Sept. 29, Judge Gloria Navarro of the US District Court for the District of Nevada, wrote that evidence submitted by the FTC “is sufficient to support a preliminary conclusion that Defendants made misrepresentations regarding their journal publishing” and conferences, and: Continue reading US court issues injunction against OMICS to stop “deceptive practices”

Director of U.S. HHS Office of Research Integrity temporarily removed from post

Kathy Partin

After a tumultuous two years, Kathy Partin is temporarily stepping away from her position as the director of the U.S. Office of Research Integrity.

According to an internal personnel announcement forwarded to us, on December 4, Partin will begin a 90-day stint at the Office of the Vice President for Research at the Uniformed Services University of the Health Sciences, which trains health professionals to support the U.S. military.

Partin declined to comment. A spokesperson for the Department of Health and Human Services (HHS), of which the Office of Research Integrity is a part, told us the agency cannot comment on personnel issues.

Linda Schutjer, a former colleague of Partin’s at Colorado State University, told us Partin was asked to leave:

Continue reading Director of U.S. HHS Office of Research Integrity temporarily removed from post

After losing two video game-violence papers, co-author’s weapons paper is flagged

Can seeing a weapon increase aggressive thoughts and behaviors?

A meta-analysis on the so-called “weapons effect” has been flagged with an expression of concern by a SAGE journal, after the researchers discovered errors affecting at least one of the main conclusions.

The paper found that the presence of weapons increased people’s aggressiveness, but not feelings of anger. However, the corresponding author, Arlin James Benjamin, who works at University of Arkansas–Fort Smith, told us:

we would urge considerably more caution in interpreting the impact of weapons on behavioral outcomes based on those initial re-analyses.

Last author Brad Bushman, a professor of communication and psychology at the Ohio State University (OSU), was the corresponding author on two now-retracted papers linking video games and violence. Continue reading After losing two video game-violence papers, co-author’s weapons paper is flagged

Journal replaces anti-vaccine paper it retracted for missing conflicts, “number of errors”

A journal retracted a paper about how conflicts of interest might be influencing research into the link between vaccines and autism because — wait for it — the authors failed to disclose conflicts of interest.

According to the retraction notice, the editors retracted the paper without the authors’ agreement, because the authors had a host of personal and professional interests in the field they didn’t declare, such as being associated with organizations involved in autism and vaccine safety. What’s more, the article also contained “a number of errors, and mistakes of various types that raise concerns about the validity of the conclusion.”

But now, Science and Engineering Ethics has published a new version of the article that draws similar conclusions to the retracted one, albeit with an updated conflict of interest statement, among other changes. From the abstract of the revised version: Continue reading Journal replaces anti-vaccine paper it retracted for missing conflicts, “number of errors”

Journal silently fixes emergency care paper — after misleading press coverage

Last month, a colleague of emergency medicine doctor Daniel Waxman sent him some newly reported findings that took him by surprise. Waxman knew from the title of a press release about the recent paper — “Nearly Half of U.S. Medical Care Comes From Emergency Rooms” — that something was wrong.

Immediately I said, that’s not true. It’s just crazy.

Waxman quickly realized the mistake: The data were based only on care provided in hospitals — much of which, not surprisingly, originates from emergency departments (EDs). But the title of the paper, the abstract, and other places in the text do not specify that. What’s more,  the press release about the study says the findings relate to “all medical care.” The journal has since changed the paper, including the title, to make that distinction clear, but not provided any editorial notice indicating the text had been updated. Meanwhile, the press release and news stories about the original study continue to report the “surprising” original findings.

Continue reading Journal silently fixes emergency care paper — after misleading press coverage