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Overlooked virus “generated a mess,” infected highly cited Cell, PNAS papers

When Alexander Harms arrived at the University of Copenhagen in August 2016, as a postdoc planning to study a type of antibiotic resistance in bacteria, he carried with him a warning from another lab who had recruited him:

People said, “If you go there, you have to deal with these weird articles that nobody believes.”

The papers in question had been published in the Proceedings of the National Academy of Sciences in 2011 and Cell in 2013. Led by Kenn Gerdes, Harms’s new lab director, the work laid out a complex chain of events that mapped out how an E. coli bacterium can go into a dormant state, called persistence, that allows it to survive while the rest of its colony is wiped out.

Despite some experts’ skepticism, each paper had been cited hundreds of times. And Harms told us:

I personally did believe in the published work. There had been papers from others that kind of attacked [the Gerdes lab’s theory], but that was not high-quality work.

But by November 2016, Harms figured out that the skeptics had been right.  Continue reading Overlooked virus “generated a mess,” infected highly cited Cell, PNAS papers

Journal investigating earlier work by author of discredited fish-microplastics paper 

A biology journal is investigating concerns about a 2014 paper by a marine biologist who was found guilty of misconduct last year.

In December, Uppsala University concluded that Oona Lönnstedt had “fabricated the results” of a controversial 2016 Science paper (now retracted), which examined the harms of human pollution on fish. (Lönnstedt’s supervisor Peter Eklöv was also found guilty of misconduct and had a four-year government grant terminated.) Continue reading Journal investigating earlier work by author of discredited fish-microplastics paper 

Cancer researcher under cloud of suspicion wins $300,000 science prize

Carlo Croce

Carlo Croce, who has had numerous papers retracted and corrected for issues including image manipulation, has received an award for more than $300,000 for his achievements in personalized medicine.

The Dan David Prize, awarded earlier this month by a charitable organization based at Tel Aviv University, bestowed $1 million to three researchers who have “made pioneering and ground-breaking discoveries in the field of personalized medicine.”

Croce, chair of the Department of Cancer Biology and Genetics at The Ohio State University, shares this year’s award with two prominent researchers—Mary-Claire King, a professor of genome sciences and medicine at the University of Washington in Seattle, and Bert Vogelstein, a professor of oncology at Johns Hopkins School of Medicine in Baltimore.

Continue reading Cancer researcher under cloud of suspicion wins $300,000 science prize

Caught Our Notice: Should publicly funded research tools be free for researchers to use?

Title: Adherence to Adjuvant Neuropathic Pain Medications in a Palliative Care Clinic

What Caught Our Attention: We’ve found a fourth retraction for the unlicensed use of a common research tool, an issue we explored in depth for Science last year. Quick recap: When researchers use a copyrighted questionnaire (MMAS-8) without permission, they get a call from its creator Donald Morisky (or his representative), asking them to pay up — sometimes thousands of dollars. There’s another option: Retract the paper. That was the choice made by a group of researchers in Arkansas, who — in a nicely detailed notice — note that, since the scale was developed using federal funds, “they dispute the validity and reasonableness of Dr. Morisky’s demands in light of the National Institutes of Health’s Principles and Guidelines for Recipients of NIH Research Grants and Contracts on Obtaining and Disseminating Biomedical Research Resources.” Continue reading Caught Our Notice: Should publicly funded research tools be free for researchers to use?

After “considerable intellectual agony,” journal retracts Wansink paper

Eduardo Franco

Ever since critics began raising concerns about high-profile food scientist Brian Wansink’s work, he’s had to issue a series of high-profile retractions — and now has his seventh (including one paper that was retracted twice, after the journal removed a revised version, along with 14 corrections). The latest notice — first reported by BuzzFeed —  is for a paper that was originally corrected by the journal Preventive Medicine earlier this month — and the correction notice was longer (1636 words) than the original, highly cited paper (1401 words). Following criticism by James Heathers about the highly cited study back in March 2017, the authors issued a series of changes, including explaining the children studied were preschoolers (3-5 years old), not preteens (8-11), as originally claimed. (They made that mistake once before, in another retracted paper.) But critics remained concerned. Yesterday, the journal retracted the paper. We spoke with editor Eduardo Franco of McGill University — who provided us with an advanced copy of an accompanying editorial, soon to be published — about the editorial processes behind the two notices, including the moment the journal knew the correction wouldn’t suffice.

Retraction Watch: You write that the initial decision to correct the paper came with “considerable intellectual agony.” Can you say why?

Continue reading After “considerable intellectual agony,” journal retracts Wansink paper

Florida investigation can’t ID culprit who falsified data in retracted PNAS paper

When the Proceedings of the National Academy of Sciences retracted a gene therapy paper in December, it declared that some of the data had been falsified and mentioned a research misconduct investigation. But the notice said nothing about who was responsible.

Via a public records request, Retraction Watch has obtained investigation documents from the University of Florida, which show the focus had been narrowed down to two of the paper’s three co-first authors. But the investigation committee didn’t assign blame to either one. According to their final report, dated Oct. 24, 2016:

there was not enough direct evidence to either implicate or exonerate either of these individuals.

Over the course of the formal investigation, which lasted from early August to late October 2016,  the committee was able to determine that data in the PNAS paper had been falsified. However, it said: Continue reading Florida investigation can’t ID culprit who falsified data in retracted PNAS paper

Chemistry journal retracts highly criticized paper

A chemistry journal has retracted a nanoparticle paper following heavy outcry from readers, who alleged the paper contained signs of obvious manipulation.

After the paper appeared in 2017, one critic lamented it contained “obviously fabricated” images, and asked the journal to retract it. Another suggested the presence of one image merited “an instant lifetime ban.”

The first comment about the paper appeared on PubPeer three months ago; earlier this month, the journal ACS Biomaterials Science & Engineering retracted the paper.

Here’s the notice:

Continue reading Chemistry journal retracts highly criticized paper

Caught Our Notice: Big journal, big correction

Title: Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery

What Caught Our Attention: When the New England Journal of Medicine (NEJM) publishes a correction that is more than a misspelling of a name, we take a look. When NEJM publishes a 500-word correction to the data in a highly cited article, we take notice. This study tested the effects of a drug to prevent blood loss in patients undergoing heart surgery; it’s been the subject of correspondence between the authors and outside experts. The correction involved tweaks — lots of tweaks — to the text and tables, which did not change the outcomes.   Continue reading Caught Our Notice: Big journal, big correction

Stanford prof plans to drop $10m suit against PNAS and critic

Mark Jacobson

A professor who is suing a journal publisher and critic for defamation has announced he plans to drop the case.

Yesterday, Stanford University professor Mark Jacobson announced on Twitter that he plans to “voluntarily dismiss the lawsuit” he filed last year in the District of Columbia, in which he alleged he was defamed when the Proceedings of the National Academy of Sciences published a paper critical of his research on the future of renewable energy. Continue reading Stanford prof plans to drop $10m suit against PNAS and critic

BMJ journal pulls case report after UK tabloids publish graphic photos

A BMJ journal has retracted a medical case report about a couple in the United Kingdom who were infected by parasitic worms while on a Caribbean cruise.

The paper in BMJ Case Reports included graphic photos of the patients’ buttocks, the site of the infection, which were republished within a week by UK tabloids.

Specifics about when and why the journal retracted the paper remains unclear. BMJ Publishing Group, the journal, and the corresponding author have not responded to multiple requests for comment.

A UK-based lawyer, who has represented doctors in cases that touch on publishing and media law, told us there could be legal trouble. Martin Soames, of London firm Simons Muirhead & Burton, told Retraction Watch that UK laws governing patient confidentiality or protection of personal information could apply, raising problems for both the publisher and the doctors who wrote the paper. [See update at the end of the post, in which the editor says the paper was removed, and “does not consider that there are any issues of liability.”]  Continue reading BMJ journal pulls case report after UK tabloids publish graphic photos