Intent was there, but not the intention-to-treat analysis: Breast cancer study retracted

A group of Dutch researchers has retracted a paper they published in March after apparently learning that they’d bungled their statistical analysis in the study.

The article, “Effects of a pre-visit educational website on information recall and needs fulfilment in breast cancer genetic counselling, a randomized controlled trial,” was published in Breast Cancer Research by Akke Albada of the Netherlands Institute for Health Services Research and colleagues.

But according to the notice, Utrecht, we have a problem: Continue reading Intent was there, but not the intention-to-treat analysis: Breast cancer study retracted

Make it a double: Alcohol treatment study pulled for duplication

European Child & Adolescent Psychiatry has retracted a 2003 paper on the treatment of alcoholism for a vague “copyright violation.” But the reason appears to be that the article was largely identical to a 2002 report from one of the authors and other colleagues.

The offending paper, “Acamprosate and its efficacy in treating alcohol dependent adolescents,” appeared in June 2003 and has been cited 51 times, according to Google Scholar. The authors were Helmut Niederhofer and Wolfgang Staffen, of the Christian Doppler-Klinik, in Salzburg.

According to the rather uninformative notice: Continue reading Make it a double: Alcohol treatment study pulled for duplication

PLoS ONE retracts paper on treatment of tissue disease for lack of ethical approval, erroneous data

PLOS ONE has retracted an article it published earlier this year by a group from Australia who failed to receive adequate ethics approval for their study.

The paper, “Late Complications of Clinical Clostridium Histolyticum Collagenase Use in Dupuytren’s Disease,” came from Warren M. Rozen, Yasith Edirisinghe and John Crock (sorry, irony machine not working today). Dupuytren’s causes thickening of the fascia in the hands and often requires surgery.  In 2011 the FDA approved a treatment for the ailment that involves injections of an enzyme — Clostridium Histolyticum Collagenase, or CHC — into the affected area.

The Aussie article looked at the effects of CHC injections in 12 patients over one year, finding that two of the patients suffered Continue reading PLoS ONE retracts paper on treatment of tissue disease for lack of ethical approval, erroneous data

Hydrogen study has “merit” — just not enough to avoid retraction

The International Journal of Hydrogen Energy has retracted a paper by a group from Malaysia and India who, reading between the lines, couldn’t quite get the low notes to overcome what the high notes lacked. Or something like that.

The paper, “Hydrogen production from sea water using waste aluminium and calcium oxide,” appears to have come out of the quaintly named 7th Petite Workshop on the Defect Chemical Nature of Energy Materials, held in March 2011 in Norway.

According to the notice: Continue reading Hydrogen study has “merit” — just not enough to avoid retraction

Data fabrication fells muscle physiology paper

Kinesiology researchers at the University of Waterloo in Canada have been forced to retract a 2010 paper in the American Journal of Physiology — Cell Physiology in the wake of revelations that the first author, then a graduate student, fabricated her data.

The paper, “ATP consumption by sarcoplasmic reticulum Ca2+ pumps accounts for 50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle,” was written by Sarah Michelle Norris and colleagues and published in March 2010.

According to the retraction notice: Continue reading Data fabrication fells muscle physiology paper

Tie Retraction Syndrome? Fat chance

Every now and then, we’re accused of “gotcha journalism” here at Retraction Watch. But here’s the story of a paper that we hope you’ll agree is “gotcha” science of the best kind, involving a different kind of retraction. The research is of, shall we say, a pressing problem known as Tie Retraction Syndrome, or TRS for short, brought to the world’s attention by a group of ophthalmologists in Germany and the UK.

According to the paper in Orbit, TRS is: Continue reading Tie Retraction Syndrome? Fat chance

Loose lips sink paper on company’s experimental pain drug

A bit of intellectual property indiscretion has led to the retraction of a paper by Korean scientists. Although the details are fuzzy, several of the authors are affiliated with a Korean pharma company called SK.

The paper, “A Novel Carbamoyloxy Arylalkanoyl Arylpiperazine Compound (SKL-NP) Inhibits Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Currents in Rat Dorsal Root Ganglion Neurons,” was published in the The Korean Journal of Physiology & Pharmacology earlier this year.

According to the retraction notice: Continue reading Loose lips sink paper on company’s experimental pain drug

ORI investigating University of Florida ob-gyn researcher accused of misconduct

A prominent researcher at the University of Florida is under federal investigation for research misconduct and has lost at least one paper as a result of the fraud.

The researcher, Nasser Chegini, was a professor of obstetrics and gynecology at the U of Florida until about six months ago, when he retired, according to the chair’s office. Nasser has received at least $4 million in federal grant funding, according to the university.

The retracted paper, “MicroRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells,” was published in 2010 by Molecular Human Reproduction. The authors were Qun Pan and Xiaoping Luo and Chegini.

As the notice explains: Continue reading ORI investigating University of Florida ob-gyn researcher accused of misconduct

Authors dispute ethical lapse in case of double physics publication that wasn’t

Plasma Processes and Polymers has retracted a paper it published in March 2012 for what it describes as a “possible breach of ethics.”

That certainly sounds bad — if inconclusive — but the authors maintain the whole thing was a simple misunderstanding.

The article, “Plasma Acid: Water Treated by Dielectric Barrier Discharge,” came from the lab of Gary Friedman, a physicist at Drexel University in Philadelphia. The first, and corresponding, author was Natalie Shainsky, an award-winning graduate student at the school.

As the notice states: Continue reading Authors dispute ethical lapse in case of double physics publication that wasn’t

Psychological Science in the news again: CNN retracts story on hormone-voting link

It’s not often that wade into retractions in the mainstream media on this blog, but in this case, we’ll make an exception.

As Politico and Poynter — and probably others — have reported, CNN has retracted a story about a yet-to-be-published study in Psychological Science claiming to find a link between estrogen and elections (disclosure: Ivan’s wife works at CNN). Specifically, the researchers reported that the well-documented preference among single women for President Obama might be rooted in their sex hormones, while that of married women for Mitt Romney seems to reflect their own ovulatory cycle. Or something like that.

Here’s the money part of the piece, which can still be found floating around on the web: Continue reading Psychological Science in the news again: CNN retracts story on hormone-voting link