Endocrinologist Shigeaki Kato resigns amidst University of Tokyo misconduct investigation

Shigeaki Kato

Shigeaki Kato, an endocrinology researcher at the University of Tokyo who retracted a paper late last month, has resigned amidst an investigation into whether he committed misconduct, Japanese media outlets are reporting.

According to the reports, the university has been investigating Shigeaki Kato and his group, affiliated with the Institute of Molecular and Cellular Biosciences, for scientific misconduct. The investigation was prompted by an outside whistleblower’s allegations in January about 24 of Kato’s papers. The whistleblower claimed that the papers manipulated and reused data improperly, and created a YouTube video to spread the word, as ScienceInsider reported earlier this year.

One of the 24 papers, Continue reading Endocrinologist Shigeaki Kato resigns amidst University of Tokyo misconduct investigation

Crise de foie: Liver journals retract duplicate biomarker pubs

Two liver journals have retracted articles from a group of Irani researchers who published similar — but not quite identical — versions of the same paper some months apart.

A retraction notice in the Journal of Gastrointestinal and Liver Diseases — which bills itself as the “Official Journal of the Romanian Societies of Gastroenterology” — explains what happened: Continue reading Crise de foie: Liver journals retract duplicate biomarker pubs

Back in the saddle: After more than 30 retractions, Naoki Mori publishing again

Naoki Mori

Perhaps it’s appropriate given the Easter season, but we have learned that Naoki Mori, the Japanese cancer researcher who received a 10-year publishing ban from the American Society of Microbiology (ASM) for imagine manipulation, has published a new paper.

Mori, who was fired and then rehired by the University of the Ryukyus over the scandal, is listed as the senior author on the paper, “Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia,” which appears in the March issue of Biochimica et Biophysica Acta. The journal, an Elsevier title, is an umbrella for nine publications in the biosciences.

Two of Mori’s retracted articles appeared in the Elsevier journals Leukemia Research and Biochemical and Biophysical Research Communications. Continue reading Back in the saddle: After more than 30 retractions, Naoki Mori publishing again

JCO expresses concern over images from Spanish group that had aroused earlier concern

The Journal of Clinical Oncology has issued an expression of concern about a 2003 article by a group of researchers in Spain who appear to have had recurrent problems with images.

The paper has been cited 56 times, according to Thomson Scientific’s Web of Knowledge. Here’s the notice:

It has been brought to our attention, regarding Figure 1, Part A, that similarity exists between bands 3, 4, and 5 of the top row and bands 1, 2, and 3 of the bottom row, including the presence of artifacts, in the April 15, 2003 article by [Jose] RomanGomez et al, entitled, “Cadherin-13, a Mediator of Calcium Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa” (J Clin Oncol 21:1472-1479, 2003).  This similarity has raised concerns about whether these rows represent independent data. We alerted the corresponding author, Dr. Roman-Gomez, of this concern, and he has repeated the experiment shown in the original Figure 1, with the results below. Although the results of the figure appear to be unchanged, we wish to inform the readers of this issue, so that they may make their own independent assessment.

Continue reading JCO expresses concern over images from Spanish group that had aroused earlier concern

Third retraction arrives for Alirio Melendez, this one in the Journal of Cellular Physiology

Alirio Melendez, the former National University of Singapore researcher who has already retracted two papers in the midst of an investigation into about 70 of his publications, has had a third retracted a third.

Here’s the notice from the Journal of Cellular Physiology: Continue reading Third retraction arrives for Alirio Melendez, this one in the Journal of Cellular Physiology

It “takes a long time to have these experiments redone,” so group retracts wheat paper after reader challenges

Normally we’d make hay with the following notice in Acta Biochimica et Biophysica Sinica — separating the wheat from the chaff, Love and Death, and all that — but, well, it speaks for itself (sort of).

A group of researchers in China have retracted their 2011 paper on the biochemistry of chloroplast in wheat: Continue reading It “takes a long time to have these experiments redone,” so group retracts wheat paper after reader challenges

Can we trust Western blots?

The title of this post is the headline of our latest column for LabTimes. It’s inspired by a number of animated discussions on Retraction Watch following our coverage of various Western blot problems — some unintentional, and some, well, less so.

Take, for example, this comment, which we quote in the column: Continue reading Can we trust Western blots?

Salami slicing and heart attacks don’t mix: Duplication, lack of transparency lead to retraction

A group of French cardiology researchers have retracted a study of a potential way to rule out heart attacks, after it became clear they had used data from another study without alerting the journal.

In an unusually forthright letter accompanying the retraction of “Concomitant measurement of copeptin and high-sensitivity troponin for fast and reliable rule out of acute myocardial infarction,” originally published in Intensive Care Medicine, Bruno Riou and colleagues note: Continue reading Salami slicing and heart attacks don’t mix: Duplication, lack of transparency lead to retraction

A “retraction in part” for Anil Potti and colleagues, in Molecular Cancer Therapeutics

A partial retraction has joined the ten retractions and five corrections of Anil Potti’s papers, this one of a 2008 paper in Molecular Cancer Therapeutics. The move comes 14 months after the retraction of the Nature Medicine paper upon which much of the Molecular Cancer Therapeutics paper was based.

Here’s the notice: Continue reading A “retraction in part” for Anil Potti and colleagues, in Molecular Cancer Therapeutics

Protein structure retracted after investigation into “highly improbable features,” journal calls it fraud

In 2010, a group of crystallographers immunologists and allergy researchers at the University of Salzburg published a paper in the Journal of Immunology claiming to have derived the structure of a birch pollen allergen.

That structure, however, caught the attention of Bernhard Rupp, an eminent crystallographer. In January of this year, Rupp submitted a paper to Acta Crystallographica Section F pointing out problems with it, which prompted the editors of the crystallography journal to contact the authors of the original paper a month later. Those authors, it turns out, agreed with Rupp, they write in a response to his paper published in the April 2012 issue of Acta Crystallographica Section F: Continue reading Protein structure retracted after investigation into “highly improbable features,” journal calls it fraud