Geneticists take HeLa sequence off-line after Lacks family notes they hadn’t given consent

g3HeLa — the cell line that has apparently taken over any number of others commonly used in science, suggesting that many researchers may not have been studying what they thought they were studying — is back in the news. This weekend, it was the DNA sequence of the cells that’s made headlines, with a quiet unpublishing of data.

As Rebecca Skloot, author of The Immortal Life of Henrietta Lacks — Lacks’s name is where “HeLa” comes from, as they’re her cells — wrote in the New York Times Sunday, a group of researchers at the European Molecular Biology Laboratory published an analysis of the HeLa cells’ genome on March 11 in G3: Genes, Genomes, Genetics, a new journal from the Genetics Society of America.

That genome, of course, could be very useful in research, given how widely used HeLa cells are. But the problem was Continue reading Geneticists take HeLa sequence off-line after Lacks family notes they hadn’t given consent

Seals of disapproval, as pinniped paper gets yanked for plagiarism

ImageJoseph Hoffman, an animal behavior researcher at the University of Bielefeld in Germany says he got a “kind of odd” feeling as he read a recent paper on the transcriptome of the spotted seal. Let’s just call it deja vu.

The article, “Characterization of the spotted seal Phoca largha transcriptome using Illumina paired-end sequencing and development of SSR markers,” which appeared in Comparative Biochemistry and Physiology Part D: Genomics and Proteomics:

Continue reading Seals of disapproval, as pinniped paper gets yanked for plagiarism

Post 982 — in which we find plagiarized bone graft paper that grafted from other papers

thesurgeonThe Surgeon has retracted a 2012 article by a group from the U.K. who took text from a previously published article. So, you say? Nu?

Well, we found — through relatively little effort — that the plagiarizees were themselves, shall we say, liberal in their use of material from other sources.

The retracted article was titled “Bone graft substitutes: What are the options?,” and it appeared in August 2012. One of the options, we guess, was to steal text.

According to the retraction notice: Continue reading Post 982 — in which we find plagiarized bone graft paper that grafted from other papers

Error scuppers paper on treatment for liver fibrosis

pharmbioPharmaceutical Biology has retracted a 2012 paper by a group of liver researchers from China after the discovery of an error that evidently invalidated the results in the paper.

The article, “Antifibrotic effects of protocatechuic aldehyde on experimental liver fibrosis,” purported to show that

protocatechuic aldehyde, the major degradation of phenolic acids … has potentially conferring antifibrogenic effects.

In other words, the compound appears to prevent the formation of liver fibroids.
But it doesn’t — at least, not according to the study — as the retraction notice explains: Continue reading Error scuppers paper on treatment for liver fibrosis

Brian Deer’s modest proposal for post-publication peer review

brian-deer-d-fullBrian Deer’s name will no doubt be familiar to many Retraction Watch readers. Deer, of course, is the award-winning investigative reporter known for his reporting on numerous medical issues, including Andrew Wakefield’s now-retracted research into autism and vaccines.

Deer is giving a talk next week at the UK’s “Evidence Live” conference,and has a proposal that he hopes will make it more difficult for dishonest researchers to hide their misdeeds — and make it easier for journals to retract fraudulent papers. He has expressed concern before that voluntary codes have no teeth. Deer is proposing an amendment to the ICMJE’s Uniform Requirements for the Submission of Manuscripts to Biomedical Journals:

Continue reading Brian Deer’s modest proposal for post-publication peer review

Flu paper duplication earns Expression of Concern

influenzaA six year-old review on bird flu that failed to credit some content from another six year-old review of bird flu is now stamped with an Expression of Concern.

Here’s the notice, from Influenza and Other Respiratory Viruses: Continue reading Flu paper duplication earns Expression of Concern

Charge of “scientific yellow journalism” has supervisor seeing red, leads to retraction

small gtpasesLast October, Anica Klockars, a neuroscience researcher at Uppsala University in Sweden, and a colleague published a controversial comment in the journal Small GTPases, a Landes Bioscience title.

The title of the letter was meant to provoke: “Scientific yellow journalism.”

As the authors wrote: Continue reading Charge of “scientific yellow journalism” has supervisor seeing red, leads to retraction

Cardiologist accused of misconduct strikes back in a journal

EBPOM_00219_M3Retraction Watch readers may recall the case of Don Poldermans, a prominent Dutch cardiology researcher who left a research position in late 2011 amid an investigation into his work. In a letter in the American Journal of Medicine titled “Scientific Fraud or a Rush to Judgement?” Poldermans — three of whose papers are subject to Expressions of Concern — tries to set the record straight, something he has tried to do before.

Poldermans is responding to an editorial by Vineet Chopra and Kim Eagle, “Perioperative Mischief: The Price of Academic Misconduct,” which Chopra and Eagle based on a November 2011 press release: Continue reading Cardiologist accused of misconduct strikes back in a journal

The “unintentionality” of being leads to nothingness for paper on protein’s role in cancer

empcoverA group of cancer researchers in Argentina has retracted a paper on the p300 protein in breast cancer that appeared in Experimental and Molecular Pathology.

The article, titled “Intracellular distribution of p300 and its differential recruitment to aggresomes in breast cancer,” was published in 2010 by Maria E. Fermento and colleagues. It has been cited 11 times since, according to Thomson Scientific’s Web of Knowledge.

Here’s the notice: Continue reading The “unintentionality” of being leads to nothingness for paper on protein’s role in cancer