Unspecified questions earn central line study an expression of concern

ajicThe American Journal of Infection Control has issued an expression of concern for a paper looking at ways to reduce infections associated with central venous catheters, or central lines.

The catheters are placed directly into a large vein and end close to the heart, allowing long-term access for medication or fluid administration. According to the CDC, infections associated with central lines cause thousands of deaths and cost billions of dollars every year.

Here’s the abstract for “Comparison of central line-associated bloodstream infection rates when changing to a zero fluid displacement intravenous needleless connector in acute care settings“: Continue reading Unspecified questions earn central line study an expression of concern

Conflict of interest, figure issues net retraction for cancer paper

am j pathologyTwo major problems sunk this cancer paper.

For one, many of the images were copied from another paper. In addition, one of the authors did not disclose that he was the president of a related company, nor that his company provided reagents for the experiments.

It’s not clear when the paper was published, but The paper was published on October 16, 2014, and a withdrawal notice went up on January 16, 2015. Here’s the retraction for “Enhanced Detection and Phenotypic and Karyotypic in Situ Characterization of Circulating Tumor Cells”: Continue reading Conflict of interest, figure issues net retraction for cancer paper

Retraction Watch “mischaracterized the reason for a retraction:” Harlan Krumholz responds to a post

Harlan Krumholz
Harlan Krumholz

On Friday, we reported on the retraction and republication of a paper in The Lancet. One of the paper’s authors, Yale’s Harlan Krumholz, took issue with how we characterized the reason for the retraction. We offered him a chance to write a guest post about the situation, which we are pleased to publish below. Please see our editor’s note at the end.

Retraction Watch has grown to play a very important role in promoting responsible conduct of scientific research. Its quest to ‘track retractions as a window into the scientific process’ performs a great service to society. They also have a great responsibility to be accurate in their characterizations of retractions, as all are not alike. I was disappointed that they, in my opinion, mischaracterized the reason for a retraction and republication of one of my papers and did not want to retract their own story (do they have a process to evaluate such concerns?).  They said that the retraction occurred because of a major statistical error, when, in my opinion, it was the result of a minor statistical error that affected the results in a very minor way and had no effect on the conclusion.  That seems like a more accurate characterization to me. And it makes a difference to the impression of what happened.

Here is the story: Continue reading Retraction Watch “mischaracterized the reason for a retraction:” Harlan Krumholz responds to a post

Weekend reads: Savage peer reviews, cosmology claim bites dust, $50 million diet pill hoax

booksThis week at Retraction Watch featured polar opposites: Two new entries in our “doing the right thing” category, and one in our plagiarism euphemism parade. Here’s what was happening elsewhere: Continue reading Weekend reads: Savage peer reviews, cosmology claim bites dust, $50 million diet pill hoax

Lancet retracts and republishes cardiology paper with admirable notice

logo_lancetOne of the papers from a massive heart disease study in China, published in the Lancet, has been retracted and republished after the authors noticed a statistical error.

The article, by authors from Peking Union Medical College in China, Yale University, and elsewhere, presented the results of the China PEACE-Retrospective Acute Myocardial Infarction Study, part of a national initiative to study and improve care for cardiac problems. After being posted online on June 24, 2014, the authors noticed that they’d incorrectly weighed one of the cities in their calculations, which threw off a number of national estimates.

After the corrections were made, the paper was peer-reviewed again, and reviewers stated that despite the mistakes, the original conclusions were sound.

Today is a banner day on Retraction Watch: This is our second excellent example of transparency in 24 hours, and therefore the second entry in our “doing the right thing” category. An editorial lays out exactly what happened, including a timeline, allowing scientists to feel confident they’re basing the next research step on solid and accurate data. (We also appreciate the hat tip to the Committee on Publication Ethics retraction guidelines, which we often send out to editors of bad notices as a gentle reminder.)

Here’s the notice for “ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data”: Continue reading Lancet retracts and republishes cardiology paper with admirable notice

Authors issue a model retraction for mistaken bacterial identity

jcmA group in the Netherlands has retracted a case study on the diarrheal pathogen Campylobacter jejuni, commonly found in animal feces, after repeated tests showed the bacteria was actually C. fetus, which also causes spontaneous abortion in cows and sheep.

The 46-year-old man who had previously had an aortic valve replacement came to the doctors with endocarditis, an inflammation of the heart. Initial tests showed that it was due to a C. jejuni infection, which often lives in chickens, wombats, kangaroos, and sheep.

Only a few cases of endocarditis caused by C. jejuni had ever been reported. Unfortunately, a thorough followup made it clear that a different pathogen was at play. Let’s consider this retraction a model for all others in its clarity and thoroughness.

Take it away, notice for “Aortic Homograft Endocarditis Caused by Campylobacter jejuni“: Continue reading Authors issue a model retraction for mistaken bacterial identity

The mysterious case of the missing — and urgent — retraction

Screen Shot 2015-01-15 at 5.09.59 PMOn January 12, we got hold of a retraction at AGRIVITA Journal of Agricultural Science a small journal published by the University of Brawijaya in Indonesia.

We went about our usual process, emailing authors and editors looking for more details. The retraction mentioned a double publication. It gave enough details that we’re fairly sure the earlier publication was this one, “Performance of Korean Soybean Varieties in Indonesia,” in the Journal of the Korean Society of International Agriculture. 

However, when we went back to write up this post, we noticed something odd. The retraction notice of “Expressions of Introduced Soybean Varieties from Korea” was no longer to be found! And the link to the paper itself now forwards you on to the main page for Agrivita.

It still shows up in Google: Continue reading The mysterious case of the missing — and urgent — retraction

Fraud retraction appears for deceased Maryland dental researcher

osomoporeA former dental researcher at the University of Maryland, Baltimore, has lost a 2009 paper in the journal Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology for fabricating his data on an NIH-funded study.

The researcher, Mark A. Scheper, is not identified in the retraction notice as the person implicated in the university investigation. However, one of his co-authors confirmed his involvement. Scheper died in January 2014 at age 45 of natural causes, according to the Maryland State Medical Examiner.

The article was titled “The oncogenic effects of constitutive Stat3 signaling in salivary gland cancer cells are mediated by survivin and modulated by the NSAID sulindac.” It appeared online in March 2009, and has been cited six times, according to Thomson Scientific’s Web of Knowledge.

According to the abstract: Continue reading Fraud retraction appears for deceased Maryland dental researcher

Bad image prompts correction of Harvard-Brigham stem cell paper by Anversa

circresA group of Harvard stem cell researchers who already have one retraction and an expression of concern now have a correction. This one’s in Circulation Research, and it involves an image that previously had been flagged as suspicious in our comments.

The group is led by Piero Anversa, who as we reported last year is one of two researchers suing Harvard because the institution’s investigation into their work

has cost them millions in a forfeited sale of their company, and job offers.

Continue reading Bad image prompts correction of Harvard-Brigham stem cell paper by Anversa

“The main improvements reported are invalid”: Quantum communication paper retracted

scientificreportsA paper on quantum communication has been retracted for failing to address several important problems, making the conclusions invalid.

Quantum communication involves sending a series of photons in specific quantum states over fiberoptic cables. It’s a little like the 1s and 0s of traditional computing, but much more secure. If the photons are intercepted on their way to the intended target, the quantum states will change, and the recipients can know their information was accessed by other parties. This is especially interesting to governments with a lot of secret information to transmit: both China and the U.S. have programs to develop these networks.

The retracted paper was a discussion of how to efficiently send lots of quantum information from different sources through the same fiberoptic cables at once.

Here’s the notice for “Efficient Quantum Transmission in Multiple-Source Networks”: Continue reading “The main improvements reported are invalid”: Quantum communication paper retracted