8 things you might not know about research misconduct proceedings: Guest post

Callan Stein

Have you ever wondered what could happen if you’re accused of misconduct and face official proceedings? We are pleased to present a guest post from Callan Stein, a lawyer who represents U.S. researchers in misconduct cases, who describes some nuances many may not realize about these situations. 

Most researchers know that being accused of research misconduct is a very serious matter. When research misconduct allegations are made, institutions embark upon lengthy, multi-staged inquiry and investigation processes as required by federal law. The federal government’s Office of Research Integrity (“ORI”) – part of the Department of Health and Human Services (HHS) – oversees those institutional findings and imposes potentially career-threatening punishments on those found guilty. While researchers generally understand the basics of how a research misconduct case unfolds, many are unaware of the nuances that bear greatly on the outcome.  What follows are brief descriptions of eight such nuances of which every researcher should be aware.

  1. While “honest error” exempts researchers from misconduct, it is very hard to prove.

Continue reading 8 things you might not know about research misconduct proceedings: Guest post

Four papers by former Wayne State researcher retracted after ORI report

Teresita L. Briones
Teresita L. Briones

Retractions have been published for four papers authored by former Wayne State University professor, Teresita L. Briones, after an April ORI report found evidence of misconduct in the articles.

Investigators found that Briones had “intentionally, knowingly, and recklessly engaged in research misconduct by falsifying and/or fabricating data.” They flagged five papers and three grant applications that contained false data.

As a result of their findings, four out of the five papers have been retracted, and the editors of the remaining journal say they are looking into the last paper.

Continue reading Four papers by former Wayne State researcher retracted after ORI report

Oregon grad student admits to faking data in four neuroscience papers

oriweb_logoA graduate student at the University of Oregon in Eugene has admitted to faking data that appeared in four published papers in the field of visual working memory, according to the Office of Research Integrity.

David Anderson’s supervisor at the time was Edward Awh, who has since moved to the University of Chicago.

Anderson told Retraction Watch that the misconduct stemmed from “an error in judgment”:

Continue reading Oregon grad student admits to faking data in four neuroscience papers

Penn State postdoc faked data in cancer manuscript

oriweb_logoA former postdoctoral fellow at Penn State University faked numerous data and analyses in a manuscript submitted to Molecular Cancer Research, according to the Office of Research Integrity (ORI).

In a notice released today, the ORI found Julie Massè: Continue reading Penn State postdoc faked data in cancer manuscript

HIV postdoc faked data in published paper, 2 grants

Julia_B
Julia Bitzegeio

An HIV researcher has admitted to faking data in a published paper, a manuscript, and two grant applications, according to a notice released today by the the Office of Research Integrity (ORI).

Former postdoc Julia Bitzegeio faked data in a 2013 paper, published in the Journal of Virology, about how HIV adapts to interferon. In the paper, “the manipulation was really minor,” Theodora Hatziioannouprincipal investigator of the lab at the Aaron Diamond AIDS Research Center (ADARC) in New York City where Bitzegeio worked, told Retraction Watch. “She just made cosmetic changes.”

The paper will be corrected, Hatziioannou said. Bitzegeio has left her lab, and her future is somewhat less clear:

Continue reading HIV postdoc faked data in published paper, 2 grants

AIDS vaccine fraudster sentenced to nearly 5 years in prison and to pay back $7 million

court case

A researcher who confessed to spiking rabbit blood samples to make the results of an HIV vaccine experiment look better has been sentenced to 57 months of prison time, according to The Des Moines Register.

Dong-Pyou Han has also been ordered to repay more than $7 million to the U.S. National Institutes of Health, and will have three years of supervised release following his prison term.

In December, 2013, the U.S. Office of Research Integrity announced that Han, formerly at Iowa State University (ISU), had faked his results to make an HIV vaccine look more powerful. The faulty data made their way into seven national and international symposia between 2010 and 2012 (resulting in a retracted poster in 2014), along with three grant applications and multiple progress reports. Han agreed to a three-year research ban, and resigned from ISU in October the following year.

The NIH never sent the final $1.38 million grant payment of more than $10 million awarded to Han’s boss, Michael Cho, and ISU returned nearly $500,000 it had received for Han’s salary and other costs.

However, Continue reading AIDS vaccine fraudster sentenced to nearly 5 years in prison and to pay back $7 million

“A decision of misconduct was reached”: Two lung papers expire

JofAnesthTwo papers about the molecular underpinnings of lung damage are being retracted following an investigation at Oita University in Japan, which revealed that images from both papers had been used to depict “different experimental conditions” in a third paper (which has not been retracted).

It’s not clear which of the authors were the subject of the investigation. The two retracted papers, “Nafamostat mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury” in the Journal of Anesthesia and “Coexpression of HSP47 Gene and Type I and Type III Collagen Genes in LPS-Induced Pulmonary Fibrosis in Rats” in Lung, both originally published in 2007, share the same first author — Satoshi Hagiwara, whose affiliation is listed as the Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine. The papers have been cited 13 times and 12 times, respectively, according to Thomson Scientific’s Web of Knowledge. Hagiwara is also the first author on the third paper that contains the duplicated images.

The first retraction notice reads:

Continue reading “A decision of misconduct was reached”: Two lung papers expire

Oregon public health employee faked 56 infection case reports: ORI

downloadA former employee in the public health division of the Oregon Health Authority committed misconduct in 56 case reports about Clostridium difficile infections in Klamath County, Oregon, as well as in a manuscript submitted to JAMA Internal Medicine and a published report in the Morbidity and Mortality Weekly Report in March, 2012.

Ryan Asherin, previously a Surveillance Officer and Principal Investigator at the OHA, was a busy man. According to the details from a report by the U.S. Office of Research Integrity, Asherin:

Continue reading Oregon public health employee faked 56 infection case reports: ORI

Brain paper retracted after university report finds “substantial data misrepresentation”

jneurosci_coverThe Journal of Neuroscience is retracting a 2012 paper on how estrogen produced in the brain shapes the auditory system on the basis of “a report from Northwestern University that describes substantial data misrepresentation” in the paper.

The paper, “Mechanistic Basis and Functional Roles of Long-Term Plasticity in Auditory Neurons Induced by a Brain-Generated Estrogen,” is, according to PubMed, the last one published by its last (and corresponding) author Raphael Pinaud, and first author Liisa Tremere, who were both at Northwestern University at the time. Before his position at Northwestern, Pinaud held positions at the University of Oklahoma and the University of Rochester.

Pinaud and Tremere jointly published a handful of papers on the role of estrogen in the auditory system of the brain starting in 2009, some of which are co-authored by two of the other researchers on the current paper, which has been cited 8 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction notice:

Continue reading Brain paper retracted after university report finds “substantial data misrepresentation”

“[W]e can learn from these bad actors:” Trail of retractions follows former Vanderbilt researcher’s fraud

JPhysiol_ak15Authors have retracted three papers from the Journal of Physiology because they contained “falsified or fabricated data.”

The papers, which address calcium signaling in heart muscle cells, are among the six pegged for retraction after an Office of Research Integrity (ORI) investigation into one of the authors, Igor Dzhura, formerly of Vanderbilt University. The ORI found that Dzhura had committed an enormous amount of fraud, involving dozens of faked images and more.

Dzhura was fired from a job at Novartis in November after the company discovered that his application had included the fraudulent work.

The three retracted Journal of Physiology papers and their citation figures, courtesy of Thomson Scientific’s Web of Knowledge, are: Continue reading “[W]e can learn from these bad actors:” Trail of retractions follows former Vanderbilt researcher’s fraud