Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

jneuroscicoverThe Journal of Neuroscience has retracted a 2012 paper by a group from Sweden’s Karolinska Institutet for what appears to be research misconduct. But more on that in a moment.

The article, “The Existence of FGFR1-5-HT1A Receptor Heterocomplexes in Midbrain 5-HT Neurons of the Rat: Relevance for Neuroplasticity,” came from the lab of Kjell Fuxe, whose interests include Parkinson’s disease, addiction and depression. The first and second authors, Dasiel Oscar Borroto-Escuela and Wilber Romero-Fernandez, are listed as being post-docs in the lab.

According to the notice: Continue reading Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

“Serious irregularities” in Western blots lead to retraction of brain chemistry paper

jneuroscijuly13The Journal of Neuroscience has retracted a 2009 article by a group from Mount Sinai (now the Icahn School of Medicine at Mount Sinai) for suspicious Western blots.

The paper, “Requirement for Protein Synthesis at Developing Synapses,” came from the lab of Deanna Benson, a Parkinson’s expert. According to the abstract, which is still available on the journal’s website:

Continue reading “Serious irregularities” in Western blots lead to retraction of brain chemistry paper

Retractions arrive for former Wash U neuroscience grad student found to have committed misconduct

Adam Savine
Adam Savine

Two studies by Adam Savine, the former Washington University neuroscience graduate student found by the Office of Research Integrity to have falsified data, have been retracted.

Here’s the notice for one: Continue reading Retractions arrive for former Wash U neuroscience grad student found to have committed misconduct

Wash U psych researcher cited in ORI probe, faces multiple retractions

Adam Savine
Adam Savine

The Office of Research Integrity says Adam Savine, a former post-doc graduate student in psychology at Washington University in St. Louis, committed misconduct in work that tainted three papers and six abstracts he submitted to conferences.

One of Savine’s studies that drew some media attention involved Diederik Stapel-esque research showing which brain region lights up when people see money. He was quoted in this 2010 article on Medical News Today saying:

“We wanted to see what motivates us to pursue one goal in the world above all others,” Savine says. “You might think that these mechanisms would have been addressed a long time ago in psychology and neuroscience, but it’s not been until the advent of fMRI about 15-20 years ago that we’ve had the tools to address this question in humans, and any progress in this area has been very, very recent.”

Apparently, now we know. According to the notice, Savine engaged in misconduct in research funded by four grants: Continue reading Wash U psych researcher cited in ORI probe, faces multiple retractions

University of Lisbon investigation that spawned neuroscience retractions found no evidence of misconduct

j neuroscienceYesterday, we reported on two retractions in the Journal of Neuroscience whose notices referred to a University of Lisbon report that had determined there was  “substantial data misrepresentation” in the original articles.  The notice didn’t say anything about misconduct, but when we see “misrepresentation,” we tend to think — as do many others — that there had been funny business.

But we heard back this morning from the senior author of the study, Ana M. Sebastião, and there’s a lot more to this story. It turns out that the University of Lisbon committee that wrote the report concluded, unanimously, that Continue reading University of Lisbon investigation that spawned neuroscience retractions found no evidence of misconduct

University of Lisbon finds “substantial data misrepresentation;” two Journal of Neuroscience papers retracted

j neuroscienceA University of Lisbon investigation has prompted two retractions in the Journal of Neuroscience.

The papers share a few authors, including senior author Ana M. Sebastião. Here’s the notice for the first paper: Continue reading University of Lisbon finds “substantial data misrepresentation;” two Journal of Neuroscience papers retracted

Journal of Neuroscience retraction, typically opaque, from author with history of errors

jneuroscienceThe Journal of Neuroscience has retracted a 2011 paper by an international group of scientists, including the prominent Maryland researcher Ronald Dubner, but readers won’t know why.

As the notice “explains“: Continue reading Journal of Neuroscience retraction, typically opaque, from author with history of errors

Canada’s Memorial U says “substantial data misrepresentation” described by retraction notice was unintentional

Yesterday, we reported on a retraction in the Journal of Neuroscience for “substantial data misrepresentation.” When we posted, the authors’ institution, Memorial University in Newfoundland, Canada, had not been able to respond to our questions yet, because of the long Canada Day weekend. This morning, they sent us the following statement, which describes the errors that led to the retraction as unintentional: Continue reading Canada’s Memorial U says “substantial data misrepresentation” described by retraction notice was unintentional

Journal of Neuroscience retracts federally funded Canadian study with “substantial data misrepresentation”

The Journal of Neuroscience is retracting a paper by researchers at Memorial University in Newfoundland, Canada, after a university investigation found “substantial data misrepresentation” in the work, which was funded by two major federal agencies.

Here’s the notice: Continue reading Journal of Neuroscience retracts federally funded Canadian study with “substantial data misrepresentation”

Does a new retraction suggest a glimmer of hope for transparency at the Journal of Neuroscience?

Believe it or not, we look for policies to praise here at Retraction Watch HQ, especially if they mark a change from approaches that we and others have criticized. So we were heartened to read this retraction notice in The Journal of Neuroscience for “Lmx1b-Controlled Isthmic Organizer Is Essential for Development of Midbrain Dopaminergic Neurons:”

The Journal of Neuroscience has received a report describing an investigation by the Shanghai Institute of Biological Sciences, Chinese Academy of Sciences, which found major data misrepresentation in the article by Guo et al. Because the results cannot be considered reliable, The Journal is retracting the paper.

The study has been cited five times since it was published in 2008, according to Thomson Scientific’s Web of Knowledge. Here’s some background on why we thought we’d have something to praise, from a Nature feature this week on retractions: Continue reading Does a new retraction suggest a glimmer of hope for transparency at the Journal of Neuroscience?