Category: clinical study retractions

Failure to disclose drug company sponsor among litany of reasons for cancer retraction

tumor biologyThis one’s a real mess.

In June, a paper in Tumor Biology was retracted for at least four reasons, including bad data and hiding a trial sponsor (Merck). Some people who contributed work weren’t cited; at least one author had no idea his name would be on it. And that’s just what they tell us in the notice.

Here’s the notice for “Neutropenia and invasive fungal infection in patients with hematological malignancies treated with chemotherapy: a multicenter, prospective, non-interventional study in China:” Continue reading Failure to disclose drug company sponsor among litany of reasons for cancer retraction

Dr. Oz: Following green coffee bean diet retraction, site scrubbed, “further study is needed”

green coffee beanOn Monday, we were first to report that a study of green coffee bean extract for weight loss touted on the Dr. Oz Show had been retracted.

That story has been widely picked up by the media, including The Washington Post, which yesterday reported that the show had posted a statement about the development: Continue reading Dr. Oz: Following green coffee bean diet retraction, site scrubbed, “further study is needed”

Doing the right thing: Authors retract PNAS paper when new experiments show “conclusion was incorrect”

pnascoverResearchers in Sweden and Australia have retracted a paper in the Proceedings of the National Academy of Sciences (PNAS) after follow-up experiments disproved their conclusions.

Here’s the notice for “Dominant suppression of inflammation by glycan-hydrolyzed IgG,” which is signed by all nine of the paper’s authors: Continue reading Doing the right thing: Authors retract PNAS paper when new experiments show “conclusion was incorrect”

Authors retract green coffee bean diet paper touted by Dr. Oz

green coffee beanTwo authors of a 2012 paper sponsored by a company that made grand claims about green coffee bean extract’s abilities to help people lose weight have retracted it. The study was cited by The Dr. Oz Show, and last month it cost the company a $3.5 million settlement with the Feds.

Here’s the notice for “Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects,” a paper originally published in Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy: Continue reading Authors retract green coffee bean diet paper touted by Dr. Oz

Journal expresses concerns over “possible data irregularities” in paper from Army medical center docs

JAADThe Journal of the American Academy of Dermatology has issued an expression of concern about a 2012 article reporting the experience of military burn unit treating a rare ailment called toxic epidermal necrolysis.

According to the notice, which is behind a paywall (for shame!), the paper appears to have overstated the number of cases the hospital itself has treated of the life-threatening condition: Continue reading Journal expresses concerns over “possible data irregularities” in paper from Army medical center docs

Authors retract HER-2 endometrial cancer paper for 2x publication

OGSFile this one under strange excuses.

A cancer paper was retracted on September 17 for a double publication. According to the notice in which the authors admit to duplicating the “opening to the readers,” which we assume is the introduction, there was no need to cite the article “because it had not yet been printed at that time.”

Here’s the notice for “The effect of HER-2 polymorphism according to age on the risk and pathologic feature of endometrial cancer”: Continue reading Authors retract HER-2 endometrial cancer paper for 2x publication

Asthma study yanked for serious ethical violations

springerplusA paper in SpringerPlus on treating asthma with antioxidants was retracted on September 25 for something of a trifecta of ethical problems.

The retraction notice indicates that the patients never consented, there was no ethical review, and the university supposedly overseeing the study had no knowledge of it:

Continue reading Asthma study yanked for serious ethical violations

Cell line switch sinks PLoS ONE cancer paper

plosWe’ve written before about how common cell line mix ups are in cancer research; according to a 2012 Wall Street Journal article (paywalled), between a fifth and a third of cancer cell lines tested by suspicious researchers turned out to be misidentified.

Obviously, mistakenly studying the wrong kind of cancer is a waste of precious resources, both time and money. And it’s clear the problem hasn’t gone away. PLoS ONE just retracted a cancer paper originally published in December 2012 for studying two cell lines that had been contaminated by other cell types.

Here’s the notice for “Epithelial Mesenchymal Transition Is Required for Acquisition of Anoikis Resistance and Metastatic Potential in Adenoid Cystic Carcinoma”:
Continue reading Cell line switch sinks PLoS ONE cancer paper

Yet another study of widely touted cancer “cure” retracted

cancer immunology immunotherapyA third study of GcMAF, a protein being used to treat a variety of conditions from AIDS to autism to cancer, all without the blessing of health agencies, has been retracted.

Here’s the notice in Cancer Immunology, Immunotherapy for “Immunotherapy of metastatic colorectal cancer with vitamin D-binding protein-derived macrophage-activating factor, GcMAF:” Continue reading Yet another study of widely touted cancer “cure” retracted

Journal makes it official, retracting controversial autism-vaccine paper

translational neurodegenerationA little more than a month after removing a highly criticized article that claimed the measles-mumps-rubella (MMR) vaccine increased the risk of autism in African American boys, Translational Neurodegeneration has officially retracted the paper.

Here’s the notice, dated yesterday: Continue reading Journal makes it official, retracting controversial autism-vaccine paper