Category: clinical study retractions

Two patch-clamping retractions in PNAS and the JCI after first author admits image manipulation

jci1212A group of cardiology researchers formerly of the University of Cologne has retracted two papers, after investigations into allegations of misconduct led to an admission of guilt by one of the lab’s junior members.

Here’s the first retraction, for “Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial KATP channels in mouse cardiomyocytes,” published last week in the Journal of Clinical Investigation: Continue reading Two patch-clamping retractions in PNAS and the JCI after first author admits image manipulation

Serial plagiarists earn lifetime publishing ban from Saudi journal

saudimedicineIn April, we wrote about a group of cancer researchers from Tunisia:

The M.O. of the group…appears to be quite simple: Find a study that looks easy to “replicate,” change a few of the particulars and submit as if it were a piece of local, original work.

One of the papers we cited in that post for appearing to be heavily plagiarized has now been retracted, with a heavy penalty for the authors. Here’s the notice, from the Annals of Saudi Medicine:  Continue reading Serial plagiarists earn lifetime publishing ban from Saudi journal

A new record: A retraction, 27 years later

jsbmbIn October, we noted the apparent record holder for longest time between publication and retraction: 25 years, for “Retention of the 4-pro-R hydrogen atom of mevalonate at C-2,2′ of bacterioruberin in Halobacterium halobium,” published in the Biochemical Journal in 1980 and retracted in 2005. (Although an author requested that another 52-year-old paper be retracted, it remains untouched in the literature.)

That record has now been broken. Congratulations to the Journal of Steroid Biochemistry and Molecular Biology and the authors of a December 1985 paper, “Increasing the response rate to cytotoxic chemotherapy by endocrine means.” Here’s the notice, which appears in the January 2013 issue of the journal, making 27 years — and a month, if you’re counting: Continue reading A new record: A retraction, 27 years later

“This publication should be ignored”: Authorship issues, flawed data fell neuro-oncology paper

Neon 2009 regular volume.inddThe Journal of Neuro-Oncology wants you to ignore the following paper: “A single chain (scFv425):sTRAIL fusion protein with specificity for the EGF receptor is effective in vitro but not in an in vivo brain tumor animal model.”

The 2007 article, from a group in The Netherlands, suffered from two fatal problems. According to the retraction notice: Continue reading “This publication should be ignored”: Authorship issues, flawed data fell neuro-oncology paper

Which came first? Plagiarism flap forces retraction of chicken nugget paper

food chem coverIt never pays to take a closer look at the inside of a chicken nugget.

The journal Food Chemistry has retracted a 2010 article by Iranian researchers who claimed to have used spectroscopy to examine the inner workings of breaded-fried chicken nuggets. Trouble was, someone else had already done the work.

Issues with the paper first surfaced in March, in the form of a correction that should have given the editors serious indigestion: Continue reading Which came first? Plagiarism flap forces retraction of chicken nugget paper

Heart retracts stent-ReoPro paper over data dispute with authors (save one)

We’re a few months late on this one, but Heart, a BMJ title, issued a fascinating retraction notice in August about a meta-analysis on percutaneous coronary intervention (that’s stenting to you and me) after suffering a heart attack, and the drug abciximab, which is used to prevent clotting and additional near-term heart attacks. Abciximab is sold as ReoPro by Eli Lilly.

The article, “Clinical impact of intracoronary abciximab in patients undergoing primary percutaneous coronary intervention: an individual patient-data pooled analysis of randomised studies,” was published last May. But according to the retraction notice, the authors had neglected to include fresh data, already in the literature before their paper went live, that contradicted their overall findings.

Here’s the notice: Continue reading Heart retracts stent-ReoPro paper over data dispute with authors (save one)

Going Dutch: Stapel inquiry eyes credulous colleagues, institution, prompts national soul search

Dutch investigators have released their final report into the case of Diederik Stapel, the social scientist and erstwhile faculty member at Tilburg University who fabricated data in 55 articles and book chapters. So far, 31 of Stapel’s published papers have been retracted — three others have expressions of concern — although more might follow.

In addition, 10 dissertations by students Stapel supervised were found to contain fraudulent data, although those students were cleared of any wrongdoing in the inquiry.

The report — and we’re going by rough translations here — found that Stapel’s colleagues and administrators seemed to accept his results at face value. Meanwhile, his high profile at Tilburg insulated him against initial rumblings about problems with his data. As the Dutch paper NRC Handelsblad reported: Continue reading Going Dutch: Stapel inquiry eyes credulous colleagues, institution, prompts national soul search

Odd: Retractions 18 and 19 for Dipak Das, and a new paper in the same journal, as if nothing were amiss

Dipak Das, the resveratrol researcher found guilty of more than 100 counts of misconduct by the University of Connecticut, has two more retractions for his resume. But that’s not the most interesting part of this post, so keep reading after the notices.

Both retractions appeared in the October 2012 issue of the Journal of Cellular and Molecular Medicine. Here’s the first notice: Continue reading Odd: Retractions 18 and 19 for Dipak Das, and a new paper in the same journal, as if nothing were amiss

Double bind: Duplication of bandaging paper leads to retraction

The Journal of Vascular Surgery is retracting — with vigor — a paper it published online in March after discovering that the authors had published essentially the same article for the Journal of the European Academy of Dermatology and Venereology some months earlier.

Both papers are titled “Randomized controlled trial comparing treatment outcome of two compression bandaging systems and standard care without compression in patients with venous leg ulcers.” The work was funded by the Health, Welfare and Food Bureau of Hong Kong and a grant from Lohmann & Rauscher GmbH & Co KG, a German company that makes compression bandages and other surgical supplies.

According to the retraction notice in JVS: Continue reading Double bind: Duplication of bandaging paper leads to retraction

“Misconduct” leads to retraction from Italian “super surgeon” under house arrest

Has the Annals of Thoracic Surgery had a change of heart? Evidently the publication that told us nearly two years ago, in effect, that the reasons for retractions in its pages were “none of [our] damn business” has decided that information is worth sharing after all.

The ATS has retracted a paper it published in October. The article, titled “Development and Validation of a New Outcome Score in Subglottic Stenosis,” came from a group of researchers in Florence, Italy.

As the notice explains: Continue reading “Misconduct” leads to retraction from Italian “super surgeon” under house arrest