Category: clinical study retractions

MD Anderson postdoc faked results of Novartis anti-cancer compound study

jun fu
Raymond Sawaya, director of MD Anderson’s brain tumor program, presents Jun Fu with the 2014 Caroline Ross Endowment Fellowship.

A former postdoc at MD Anderson Cancer Center faked the results of a mouse study of a Novartis compound designed to fight brain tumors, according to the Office of Research Integrity (ORI).

Jun Fu “admitted to knowingly and intentionally falsifying Figure 8a” in “Novel HSP90 Inhibitor NVP-HSP990 Targets Cell-Cycle Regulators to Ablate Olig2-Positive Glioma Tumor–Initiating Cells,” a paper published in Cancer Research on May 15, 2013:

Continue reading MD Anderson postdoc faked results of Novartis anti-cancer compound study

UT-Southwestern cancer research group notches ninth retraction

lung cancerA research team at the University of Texas-Southwestern that has retracted eight papers for image manipulation has retracted another, this one in Lung Cancer.

Here’s the notice for “Aberrant methylation of Reprimo in lung cancer,” published by Adi Gazdar’s group: Continue reading UT-Southwestern cancer research group notches ninth retraction

Authors retract paper “confirming” that narcolepsy is an autoimmune disease

stmA group of researchers at Stanford and elsewhere is retracting a 2013 paper that another scientist told Nature was “one of the biggest things to happen in the narcolepsy field for some time.”

The Science Translational Medicine paper caused a buzz because it claimed to show that narcolepsy was an autoimmune disease. Here’s the notice: Continue reading Authors retract paper “confirming” that narcolepsy is an autoimmune disease

“Authors, please call us. Pretty please? OK, we’re going to retract your paper!”

dovelogoThe title of this post isn’t exactly how the one-sided conversation between the editors of Neuropsychiatric Disease and Treatment and a group of researchers went. But it seems likely it was pretty close.

Here’s an expression of concern for “A cross-sectional study on perception of stigma by Chinese schizophrenia patients:” Continue reading “Authors, please call us. Pretty please? OK, we’re going to retract your paper!”

“Positivity ratio” research now subject to an expression of concern

An expression of concern has been issued for the second of three papers on the idea that, if you have three positive emotions for every negative one, you will be more successful in life.

Psychologist Barbara Fredrickson, of the University of North Carolina, Chapel Hill, has spent the last decade building a brand around this ratio, initially described by a mathematical equation based on fluid dynamics by mathematician Marcial Losada. You can read our coverage of the debunking of that equation, presented in a 1999 paper that has been cited nearly 1,700 times, here.

Nick Brown, co-author with Alan Sokal on the paper that discredited the Losada equation, has written a blog post on the current state of affairs. He also got in touch with us regarding the expression of concern for a 2004 article in American Behavioral Scientist that he had also questioned, “The Role of Positivity and Connectivity in the Performance of Business Teams: A Nonlinear Dynamic Model”: Continue reading “Positivity ratio” research now subject to an expression of concern

Diabetes researcher Cory Toth up to seven retractions

tothA University of Calgary diabetes researcher, Cory Toth, who told us earlier this year that he would cease publishing in the scientific literature, has two more retractions, making seven.

Both appear in Neurobiology of Disease. Here’s the notice for “Differential impact of diabetes and hypertension in the brain: Adverse effects in white matter:”
Continue reading Diabetes researcher Cory Toth up to seven retractions

Paper about widely touted but unapproved “cure” for cancer, autism retracted

int j cancerA paper about a protein being used — unapproved by health agencies — to treat diseases including cancer and autism has been retracted.

Here’s the notice from the International Journal of Cancer about a 2007 paper purporting to show that the substance, GcMAF, is useful against breast cancer: Continue reading Paper about widely touted but unapproved “cure” for cancer, autism retracted

“Lack of experience and understanding” forces duplication retractions of liver cancer paper

dovelogoA group of researchers in China has lost their paper on liver cancer after the first author admitted to duplication, also known, inelegantly, as self-plagiarism.

The paper, “Glycyrrhetinic acid-modified chitosan nanoparticles enhanced the effect of 5-fluorouracil in murine liver cancer model via regulatory T-cells,” appeared in the July 2013 issue of the Journal of Drug Design, Development and Therapy, a Dove Press title.

According to the abstract: Continue reading “Lack of experience and understanding” forces duplication retractions of liver cancer paper

Yogurt to be kidding me: Five articles plagiarized in one retracted paper

After typing up 96 citations, researchers from the National Institute for Digestive Diseases, I.R.C.C.S. “S. de Bellis,” in Bari, Italy, apparently ran out of steam for the last five, earning themselves a retraction for plagiarism in a literature review of the effects of probiotics on intestinal cancer.

Here’s the notice for “Intestinal Microbiota, Probiotics and Human Gastrointestinal Cancers,” from the Journal of Gastrointestinal Cancer: Continue reading Yogurt to be kidding me: Five articles plagiarized in one retracted paper

Rice researcher in ethics scrape threatens journal with lawsuit over coming retraction

Guangwen Tang, a rice researcher at Tufts University, landed in hot water in 2012 after her team was accused of feeding Chinese children genetically modified Golden Rice without having obtained informed consent from the parents.

Now, she’s suing both Tufts and the American Journal of Clinical Nutrition, which reportedly is retracting a paper, “ß-carotene in Golden Rice is as good as p-carotene in oil at providing vitamin A to children,” based on the federally funded research, claiming that the retraction would constitute defamation. (That retraction hasn’t happened yet.)

This isn’t the first time we’ve heard the retraction = defamation line. Readers might remember Ariel Fernandez, who threatened to sue us for writing about an expression of concern. Maybe a course on the Streisand Effect should be mandatory for PhD students?
Continue reading Rice researcher in ethics scrape threatens journal with lawsuit over coming retraction