Three more withdrawals for Naoki Mori, and a hint of the mother of retractions

Lest readers of Retraction Watch had forgotten about Naoki Mori, the cancer researcher who liked his Western blots so much he decided to reuse them — and reuse them some more — he’s back.

The British Journal of Haematology (BJH) has retracted two papers Mori published in that journal, and BMC Microbiology has retracted another, bringing the total of retractions involving his work to at least 19 by our count. [See update at end.]

The BJH issued both retractions online in the end of February, and they’ve since come out in print. Here’s the retraction notice for the first paper, in the BJH (first only because it was published first): Continue reading Three more withdrawals for Naoki Mori, and a hint of the mother of retractions

So when is a retraction warranted? The long and winding road to publishing a failure to replicate

Sometime in 2009, the University of Nottingham’s Uwe Vinkemeier thought something was wrong with two papers he read in Genes & Development, one from 2006 and one from 2009. The papers claimed to show how changes to a protein called STAT1 affect programmed cell death. So he did what scientists are supposed to do: He tried to repeat the experiments, to replicate the results.

He couldn’t.

So he submitted the results to G&D, which was initially willing to publish the data along with a rebuttal by the original authors. But everyone seemed to be dragging their feet. Continue reading So when is a retraction warranted? The long and winding road to publishing a failure to replicate

On second thought: PNAS retracts two papers after results fail replication

The Proceedings of the National Academy of Sciences (PNAS) ran two retractions this week.

One of those papers was “Properdin homeostasis requires turnover of the alternative complement pathway,” which first appeared online in October of last year. The researchers were looking at the interaction between complement — a sort of primitive immune system — and a protein called properdin.

From the notice: Continue reading On second thought: PNAS retracts two papers after results fail replication

Another Bulfone-Paus paper under review, this one in Blood

Blood tells Retraction Watch that they are reviewing a 1999 paper co-authored by Silvia Bulfone-Paus, who has already retracted 12 papers in other journals.

The study, “Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15,” has been cited 124 times, according to Thomson Scientific’s Web of Knowledge. Its corresponding author is Tiziana Musso, of the University of Turin.

Joerg Zwirner, over at the Abnormal Science blog, has a three-part series deconstructing what he says are the flaws in the paper. Zwirner points out a number of data duplications. As he notes: Continue reading Another Bulfone-Paus paper under review, this one in Blood

No confidence vote on sepsis paper data leads to Blood retraction

The journal Blood has retracted an article after the authors determined that they could not longer trust in the validity of the data.

The paper has been cited 22 times, according to Thomson Scientific’s Web of Knowledge. From the retraction notice:

Niessen F, Furlan-Freguia C, Fernández JA, Mosnier LO, Castellino FJ, Weiler H, Rosen H, Griffin JH, Ruf W. Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality.

Blood. 2009;113(12):2859-2866.

The authors retract the 19 March 2009, paper cited above. Recently, the authors discovered that some primary data presented in this paper could not be independently reproduced. All coauthors concur with the retraction of the paper and apologize to the readers, reviewers, and editors of Blood for publishing these invalid data.

The nature of the data problem isn’t clear from that passage. But Blood editor Cynthia Dunbar told us that her journal Continue reading No confidence vote on sepsis paper data leads to Blood retraction

Borstel hit with more potential misconduct as managing director steps down amid questions of plagiarism

Peter Zabel/Borstel

Retraction Watch readers are likely to be familiar with Germany’s Research Center Borstel, because it is home to Silvia Bulfone-Paus, who has recently retracted 12 papers. Now it turns out that Borstel’s managing director, Peter Zabel — who was involved in the Bulfone-Paus investigation — has stepped down because of allegations of duplication of his own work.

According to a statement from Borstel, translated from German: Continue reading Borstel hit with more potential misconduct as managing director steps down amid questions of plagiarism

Chemist: “corresponding author should answer” questions regarding retracted papers

We have an update to our coverage of the retractions involving papers from a group of researchers in Iran that were published in Computational and Theoretical Chemistry (formerly called the Journal of Molecular Structure: THEOCHEM)

Although we have not received a response from the first author of those studies, Siavash Riahi, one author, Mohammad Reza Ganjali, of the Center of Excellence in Electrochemistry at the University of Tehran, sent us a lengthy comment recently. We post his remarks in their entirety here, unedited: Continue reading Chemist: “corresponding author should answer” questions regarding retracted papers

Four genetics papers retracted for duplication

Petter Portin, of the University of Turku, Finland, has been forced to retract four papers because they were duplicates of work he had already published.

Two of those retractions appear in the February 2011 issue of Hereditas. Here’s one retraction notice (link added):

The following article from Hereditas: Portin, P. ‘The effect of the mus309 mutation, defective in DNA double-strand break repair, on crossing over in Drosophila melanogaster suggests a mechanism for interference’, published online in Wiley Online Library (http://onlinelibrary.wiley.com/) on 1 September 2009, Hereditas, volume 146, pp. 162–176, has been retracted by agreement between the author, the Editor-in-Chief, Anssi Saura, and John Wiley & Sons A/S. The retraction has been agreed due to prior publication of a similar article in Genetica.

And the other (link added): Continue reading Four genetics papers retracted for duplication

Bulfone-Paus saga continues: Her supporters and home institution exchange sharp letters

Silvia Bulfone-Paus

Retraction Watch readers may have been following the case of Silvia Bulfone-Paus, whose lab has been forced to retract 12 papers amid allegations of scientific misconduct. As is often true in such cases, the story doesn’t end with those retractions. We’ve just become aware of a fascinating exchange in March and April between Bulfone-Paus’s supporters and her home institution, Germany’s Research Center Borstel.

First, some background: Karin Wiebauer, a former post-doc in Bulfone-Paus’s lab, flagged the potential misconduct, in great detail, for Bulfone-Paus in a November 2009 email. (In fact, she had brought it to her attention years earlier.) But Bulfone-Paus did not tell Borstel officials about the allegations until late February 2010. Borstel’s investigation into Bulfone-Paus’s lab began in July 2010.

Once that began, a person referring to himself as “Marco Berns” began emailing officials, journalists, and others about the situation. Nature called that move a “smear campaign,” and the emails “libellous,” but in retrospect they — and Wiebauer’s analysis — appear to have been spot-on, based on the eventual report of the Borstel committee. That report — which found data manipulation by two of Bulfone-Paus’s post-docs — led the institute’s Scientific Advisory Board to ask for Bulfone-Paus’s resignation. She only tendered that a month later, after more pressure.

So, with that as a preamble: If we were to characterize the letter, which we’ve made available here, we’d call it a good example of “shoot the messenger.” It’s signed by 25 scientists, starting with Desmond Tobin of the University of Bradford in the UK and ending with Andrzej Slominski of the University of Tennessee. Continue reading Bulfone-Paus saga continues: Her supporters and home institution exchange sharp letters

Three more chemistry papers fall to “serious errors” of unknown nature

Back in March, we reported that the journal Computational and Theoretical Chemistry (CTC) had retracted a pair of 2006 papers by a group of Iranian researchers. As the notices stated, the scientists had recalled their articles after detecting “serious errors” with the work post-publication.

At the time, the authors still had three other articles in good standing with CTC. No longer.

CTC has retracted the remaining three papers by the group, for the same “serious errors.” The articles appeared between 2007 and 2009, and were titled: Continue reading Three more chemistry papers fall to “serious errors” of unknown nature