Family squabble over safety of eye therapy forces journal to pull paper

Screen Shot 2016-03-11 at 5.41.35 PM

A father and son are fighting over whether a laser therapy they describe as co-authors of a 2015 paper could be harmful to patients, prompting the journal to retract the article.

The small study suggested that the therapy could safely treat patients with glaucoma. But Tomislav Ivandic — the father — alleges that errors in how the study was reported could lead to harmful doses of laser light for patients receiving the therapy. His son and co-author, Boris Ivandic, maintains that the article is accurate.

To err on the side of patient safety, Photomedicine and Laser Surgery retracted “Effects of Photobiomodulation Therapy on Patients with Primary Open Angle Glaucoma: A Pilot Study.”

The retraction note explains the dispute:

Continue reading Family squabble over safety of eye therapy forces journal to pull paper

Biologist’s research under investigation in Sweden after being questioned on PubPeer

Holgersson
Suchitra Sumitran-Holgersson

The University of Gothenburg in Sweden is investigating several papers co-authored by biologist Suchitra Sumitran-Holgersson after they were challenged on PubPeer.

Sumitran-Holgersson already has one retraction under her belt — of a 2005 Blood paper, after another investigation concluded the results “cannot be considered reliable.” Sumitran-Holgersson and her husband, co-author Jan Holgersson, did not sign the retraction notice. Both were based at the Karolinska Institutet (KI) at the time, but have since moved to the University of Gothenburg.

Now, the University of Gothenburg has launched its own investigation of the papers questioned on PubPeer, according to Continue reading Biologist’s research under investigation in Sweden after being questioned on PubPeer

Macchiarini dismissed from Karolinska

Paolo Macchiarini
Paolo Macchiarini

The Karolinska Institutet has dismissed former rising star surgeon Paolo Macchiarini from his post, effective immediately.

A KI news release, dated today, states:

The Staff Disciplinary Board at Karolinska Institutet has today decided to relieve Paolo Macchiarini of his duties as a researcher at KI. He is to be informed immediately that his contract has been rescinded.

For a refresher on the story, check out our constantly updating timeline. As a brief recap: Continue reading Macchiarini dismissed from Karolinska

NEJM: No plan to clarify wording that led to allegations of breached confidentiality

NEJMThe New England Journal of Medicine (NEJM) has no plans to change the wording of an article that led to allegations of breached patient confidentiality and caused a minor social media firestorm this past weekend, the journal told Retraction Watch.

The paragraph in question appeared in an essay by Lisa Rosenbaum chronicling the history of power morcellation, a technique to remove gynecological organs that the FDA has subjected to a “black box warning” because it can also spread tumors: Continue reading NEJM: No plan to clarify wording that led to allegations of breached confidentiality

Journal bans 8 authors for plagiarism

67

A medical journal has banned eight authors after discovering that they had published plagiarized work.

We don’t see official author bans as often as we see plagiarism (occasionally, and all the time, respectively). That’s why we’re flagging this case, which is a little old — the International Journal of Medical Science and Public Health announced the ban in March 2015, after it retracted three of the authors’ papers for plagiarism.

All three papers — about recovering from orthopedic problems — have a first author in common: Rajesh Valjibhai Chawda, who was affiliated with the CU Shah Medical College and Hospital in India at the time of the research. (We couldn’t find a webpage for him.)

After an author on one of the original articles alerted the journal of one instance of plagiarism, the journal launched an in-house inquiry, the retraction note explains:

Continue reading Journal bans 8 authors for plagiarism

Surgery studies lacked ethics committee approval

3Surgery Today has pulled a pair of papers that share many authors because the studies they describe were not approved by an institutional ethics committee.

One describes a case in which the researchers removed a mass from a 64-year-old woman’s small intestine; the other describes how the authors removed a growth from a patient’s pancreas. They conclude that the surgery techniques used — like a laparoscopic pancreaticoduodenectomy, a take on the “Whipple Procedure” — can be “feasible, safe, and effective” in certain patients.

The papers share several authors, including a first author, Akihiro Cho, whose affiliation on the papers is Chiba Cancer Center Hospital in Japan. They also share a retraction note, which explains how the journal learned of the issue:

Continue reading Surgery studies lacked ethics committee approval

Macchiarini may be dismissed from Karolinska; dean of research resigns

Paolo Macchiarini
Paolo Macchiarini

There’s more news to report on the story of surgeon Paolo Macchiarini, who’s been dogged by allegations of misconduct.

After the Karolinska Institutet (KI) announced it would not extend his contract and that he needed to “phase out” his research by November, it has now announced it may dismiss him.

In addition, Hans-Gustaf Ljunggren, KI’s Dean of Research, has resigned.

Here’s the statement we received from a KI spokesperson:

Continue reading Macchiarini may be dismissed from Karolinska; dean of research resigns

Don’t perform heart surgery described in retracted paper, says editor

Screen Shot 2016-02-08 at 10.53.50 PMA journal is retracting a paper about a heart surgery technique after discovering the researchers did not have ethics approval to perform a the procedure on 130 patients. What’s more, the local cardiac surgical society had asked the first author to stop using the method in 2004, six years before the study was complete.

The patients in the study had atrial septal defects — a congenital hole in their hearts that allows blood to leak between chambers. The retraction note concludes with the editor in chief advising other surgeons to not use the method to close the hole described in the retracted article, “Long-term assay of off-pump atrial septal defect closure using vena caval inflow occlusion and minimally invasive approaches in 130 cases.

A concern from a reader unraveled the paper. The retraction note explains how:

Continue reading Don’t perform heart surgery described in retracted paper, says editor

Why publishing negative findings is hard

Jean-Luc Margot
Jean-Luc Margot

When a researcher encountered two papers that suggested moonlight has biological effects — on both plants and humans — he took a second look at the data, and came to different conclusions. That was the easy part — getting the word out about his negative findings, however, was much more difficult.

When Jean-Luc Margot, a professor in the departments of Earth, Planetary & Space Sciences and Physics & Astronomy at the University of California, Los Angeles, tried to submit his reanalysis to the journals that published the original papers, both rejected it; after multiple attempts, his work ended up in different publications.

Disagreements are common but crucial in science; like they say, friction makes fire. Journals are inherently disinterested in negative findings — but should it take more than a year, in one instance, to publish an alternative interpretation to somewhat speculative findings that, at first glance, seem difficult to believe? Especially when they contain such obvious methodological issues such as presenting only a handful of data points linking biological activity to the full moon, or ignore significant confounders?

Margot did not expect to have such a difficult experience with the journals — including Biology Letters, which published the study suggesting that a plant relied on the full moon to survive: Continue reading Why publishing negative findings is hard

Karolinska vice-chancellor resigns following criticism of Macchiarini investigation

Anders Hamsten
Anders Hamsten

Anders Hamsten announced he would be resigning as vice-chancellor from Karolinska Institutet (KI) in the early hours of Saturday, February 13.

In a press release we received at 12:16 a.m. local time in Stockholm, Hamsten issued the following statement:

Following the criticism on the so called Macchiarini affair at KI I conclude it will be hard for me to serve as Vice-Chancellor with the strength and credibility this university needs. I will therefore leave office.

Good thing we published a primer on the whole story a few hours ago. To recap: Continue reading Karolinska vice-chancellor resigns following criticism of Macchiarini investigation