Category: clinical study retractions

When it comes to retracting papers by the world’s most prolific scientific fraudsters, journals have room for improvement

Journals have retracted all but 19 of the 313 tainted papers linked to three of the most notorious fraudsters in science, with only stragglers left in the literature. But editors and publishers have been less diligent when it comes to delivering optimal retraction notices for the affected articles.

That’s the verdict of a new analysis in the journal Anaesthesia, which found that 15% of retraction notices for the affected papers fail fully to meet standards from the Committee for Publication Ethics (COPE). Many lacked appropriate language and requisite watermarks stating that the articles had been removed, and some have vanished from the literature.

The article was written by U. M. McHugh, of University Hospital in Galway, Ireland, and Steven Yentis, a consultant anaesthetist at Chelsea & Westminster Hospital in London. Yentis was editor of Anaesthesia during the three scandals and had a first-hand view of two of the investigations. He also is the editor who unleashed anesthetist and self-trained statistician John Carlisle on the Fujii papers to see how likely the Japanese researcher’s data were to be valid (answer: not very likely). Continue reading When it comes to retracting papers by the world’s most prolific scientific fraudsters, journals have room for improvement

Distraction paper pulled for clerical error

The authors of a 2018 paper on how noisy distractions disrupt memory are retracting the article after finding a flaw in their study.

The paper, “Unexpected events disrupt visuomotor working memory and increase guessing,” appeared in Psychonomic Bulletin & Review, a publication of the Psychonomic Society. (For those keeping score at home, psychonomics is the study of the laws of the mind.)

The article purported to show that an unexpected “auditory event,” like the sudden blare of a car horn, reduced the ability of people to remember visuomotor cues. Per the abstract:

Continue reading Distraction paper pulled for clerical error

Researchers pull Nature paper over first author’s objections

Researchers have retracted a 2015 Nature paper about the molecular underpinnings of immune function after discovering they could not replicate key parts of the results.

The first author, Wendy Huang — who started working as an assistant professor at the University of California, San Diego, only months after the paper appeared — did not sign the retraction letter, published last week. The research was conducted while Huang was working as a postdoctoral fellow at New York University, home of last author Dan Littman (also an investigator at the Howard Hughes Medical Institute).

What happened appears to be a case of “he said, she said:” Littman asked to retract the paper after his lab couldn’t reproduce it, and Huang insists the data remain correct, saying the process had been “unfair and done without due process:”

Continue reading Researchers pull Nature paper over first author’s objections

A university went to great lengths to block the release of information about a trial gone wrong. A reporter fought them and revealed the truth.

Jodi S. Cohen

Here’s a story that shows the lengths a public university — The University of Illinois at Chicago — went to block the release of information about a child psychiatry trial gone wrong, and how a reporter — Jodi S. Cohen of ProPublica — fought them effectively at every turn to reveal the truth.

Earlier this year, ProPublica “revealed that the National Institute of Mental Health ordered the university to repay $3.1 million in grant money it had received to fund [Mani] Pavuluri’s study.” This kind of clawback is very, very rare.

We tipped our hats to Cohen then, because we had been trying for years to obtain documents that would tell the full story of the Pavuluri case, which we had been covering since 2015 when a retraction appeared. In particular, we’ve been trying to get the university to release their report of the investigation into Pavuluri’s work. We have been making a push for such reports, as we noted earlier this week in a roundup of more than 16 of them. Continue reading A university went to great lengths to block the release of information about a trial gone wrong. A reporter fought them and revealed the truth.

Fecal transplant paper pulled for “personal issue”

Last month, the Journal of Pediatric Gastroenterology and Nutrition pulled an article on fecal transplantation for a reason that, well, doesn’t pass the sniff test.

The paper, by Sonia Michail of Children’s Hospital Los Angeles, appeared online in October 2017 and described a randomized controlled trial of fecal transplants to treat kids with ulcerative colitis. (If you’re interested, here’s an overview of how fecal transplantation works.) The trial, or one awfully like it, is listed on ClinicalTrials.gov, and shows Michail as the lone investigator on the study, which is aiming to gather more than 100 participants.

But the journal retracted the article — which was the subject of a laudatory editorial in the journal pointing readers to the findings — with an entirely opaque statement, saying that the work   

Continue reading Fecal transplant paper pulled for “personal issue”

Journal holds firm on decision not to retract Macchiarini paper, despite outside pressure

Earlier this year, the president of the Karolinska Institute, Ole Petter Ottersen, contacted the journal Respiration, saying KI had conducted an investigation and determined that a 2015 paper co-authored by once-lauded surgeon Paolo Macchiarini had been tainted by misconduct. Please retract the paper, Ottersen said. When the journal said no — opting to publish correspondence from KI and the authors’ response instead — Ottersen posted some of their correspondence online, in an attempt to pressure the journal to do the right thing. It’s not going to work, according to Thomas H. Nold, publication manager at Karger, which publishes Respiration. We spoke to Nold about the journal’s plans for the paper.

Retraction Watch: How do you feel about KI’s decision to publish your correspondence?

Continue reading Journal holds firm on decision not to retract Macchiarini paper, despite outside pressure

Does the Mediterranean diet prevent heart attacks? NEJM retracts (and replaces) high-profile paper

The New England Journal of Medicine has retracted a 2013 paper that provided some proof that the Mediterranean diet can directly prevent heart attacks, stroke, and other cardiovascular problems.

The original paper, “Primary Prevention of Cardiovascular Disease with a Mediterranean Diet,” has been cited 1,759 times, according to Clarivate Analytics’ Web of Science.

But the findings haven’t disappeared — the authors have replaced the paper with a new version, which softens its earlier claims. Continue reading Does the Mediterranean diet prevent heart attacks? NEJM retracts (and replaces) high-profile paper

Journals flag two papers by prominent researcher — who is also on trial for domestic abuse

Adeel Safdar was once a rising star in the field of kinesiology. After completing his doctorate degree at McMaster University in Canada, working with one of the titans of his field, Safdar took a postdoc at Harvard, then accepted a newly created chair position at another university in Ontario.

That all came crashing down last year, when Safdar went on trial in Canada, accused of horrifically abusing his wife. Over the course of the trial, allegations arose about his research, prompting two journals to flag papers he co-authored with his former mentor, Mark Tarnopolsky.

Tarnopolsky — author of more than 400 papers, which have collectively been cited more than 17,000 times, according to Clarivate Analytics’ Web of Science — told Retraction Watch:

Continue reading Journals flag two papers by prominent researcher — who is also on trial for domestic abuse

Karolinska told a journal to retract a paper by Macchiarini. It refused. The story didn’t end there.

The president of the Karolinska Institutet (KI) is frustrated.

At the beginning of the year, Ole Petter Ottersen informed a journal that one of its papers — co-authored by former superstar Paolo Macchiarini — had been tainted by misconduct. But the journal declined to retract it.

Despite the fact that KI had conducted its own investigation into the integrity of the paper, the journal Respiration argued that it was “not in a position to make a judgement on whether or not to retract this article.” Instead, it proposed publishing KI’s argument for why the paper should be retracted, along with a rebuttal from the authors.

To Ottersen, this is just wrong. Yesterday, he posted some of his correspondence with the journal, which includes his request for retraction, the journal’s response, and his rebuttal. Ottersen’s blog post concludes:

Continue reading Karolinska told a journal to retract a paper by Macchiarini. It refused. The story didn’t end there.

How much cancer stems from diabetes, obesity? Lancet journal swaps high-profile paper

Six months ago, the media was ablaze with the findings of a new paper, showing that nearly six percent of cancer cases are caused, at least in part, by obesity and diabetes. But this week, the journal retracted that paper — and replaced it with a revised version.

The new paper doesn’t change the main findings much — the share of all cancers attributable to diabetes and obesity changed from 5.6% to 5.7%, which wouldn’t change any headlines about the original paper. But soon after the paper was published, a group of researchers noticed the authors’ mistake — which was significant enough to prompt the journal to retract the paper entirely, and swap it with a new one.

According to first author Jonathan Pearson-Stuttard at Imperial College London:

Continue reading How much cancer stems from diabetes, obesity? Lancet journal swaps high-profile paper