Heart study pulled after production glitch leads to duplicate publication

On reflection, that headline pretty much says it all. But for those readers who took the time to click on the link, here’s the rest of it.

The journal Heart, a title of the BMJ group, has retracted a paper that it published twice: Continue reading Heart study pulled after production glitch leads to duplicate publication

Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

via Wikimedia

PLoS One and Nature Medicine have issued corrections for papers by Zhiguo Wang, the former Montreal Heart Institute researcher who resigned in September following an investigation into image manipulation in his lab. 

In September, PLoS One told us that they were investigating the paper. Here’s the text of the correction for “Transcriptional and Post-Transcriptional Mechanisms for Oncogenic Overexpression of Ether À Go-Go K+ Channel:” Continue reading Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

Zhiguo Wang retractions appear in the Journal of Cellular Physiology

Last month, we reported that the last three of six promised retractions by Zhiguo Wang, who was a researcher at the Montreal Heart Institute until the results of an Institute investigation forced him to resign in early September — would be in the Journal of Cellular Physiology. They’ve now appeared.

Here are the three notices, which are far more informative than the Journal of Biological Chemistry was — and which make it clear Wang acted alone: Continue reading Zhiguo Wang retractions appear in the Journal of Cellular Physiology

Florida group loses second hypertension paper, but retraction notice stays mum on why

We’ve obviously gotten plenty of mileage out of our conversation last January with L. Henry Edmunds, the grumpypants editor of the Annals of Thoracic Surgery who told us that the reason behind an opaque retraction notice in his journal was “none of  [our] damn business.”

Still makes us chuckle.

That episode came to mind recently when we learned of a new retraction, this one in the journal Perfusion, involving the same lead researcher, anesthesiologist Felipe Urdaneta, whose work Edmunds had pulled. Continue reading Florida group loses second hypertension paper, but retraction notice stays mum on why

Remaining Zhiguo Wang retractions will be in the Journal of Cellular Physiology

We’ve been following the case of Zhiguo Wang, the former Montreal Heart Institute researcher who was forced to resign his post in early September following an investigation into his work. At the time of that announcement, two retractions of the Wang group’s papers — which we had reported on in August — had appeared. The Institute said they had requested three more.

We figured that meant a total of five, although the Institute wouldn’t say which they were. So when we found out about a third retraction, in the Journal of Cell Science, we said it was the first of the remaining three.

We were wrong. Continue reading Remaining Zhiguo Wang retractions will be in the Journal of Cellular Physiology

Nature Medicine paper by former Montreal Heart Institute researcher Zhiguo Wang unlikely to be retracted

We’ve been reporting on the case of Zhiguo Wang, the Montreal Heart Institute researcher who was dismissed earlier this month for scientific misconduct. In the announcement about Wang’s dismissal, the institute said it had requested the retraction of three papers other than the two that Wang had himself retracted earlier this summer, making a total of five.

We’ve been following up with journals that published Wang’s work, with the help of eagle-eyed Retraction Watch readers, and last week reported on the first of those three additional retractions, in the Journal of Cell Science. Late last week, we heard from Juan Carlos Lopez, the chief editor of Nature Medicine, which had published a paper by the group. Lopez had earlier said he was waiting for a Montreal Heart Institute report on their findings. He tells us it’s unlikely the Nature Medicine paper will be among those retracted: Continue reading Nature Medicine paper by former Montreal Heart Institute researcher Zhiguo Wang unlikely to be retracted

Montreal Heart Institute researcher dismissed following two retractions for image manipulation

A Montreal Heart Institute researcher who retracted two papers less than a month ago has been fired from his post.

Zhiguo Wang, who had been funded by the Canadian Institute of Health Research and the Canadian Diabetes Association, studied the genes linked to heart rhythm abnormalities, among other subjects. Wang also has an appointment at the University of Montreal.

As first reported in Retraction Watch, Wang withdrew two papers for the Journal of Biological Chemistry (JBC) in the journal’s August 12 issue. The story was quickly picked up by Postmedia and the CBC. At the time, Wang told us: Continue reading Montreal Heart Institute researcher dismissed following two retractions for image manipulation

Authors retract two JBC papers on how heart rhythms go awry; Montreal Heart Institute looking into why

The authors of two Journal of Biological Chemistry (JBC) studies of the molecular underpinnings of hearts whose rhythms have gone awry have retracted the papers, for reasons that are not completely clear.

The two papers are  “MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts,” published in 2007, and “Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart,” published in 2008.

This being the JBC, the retraction notices in the August 12, 2011 issue say nothing: Continue reading Authors retract two JBC papers on how heart rhythms go awry; Montreal Heart Institute looking into why

German paper on inflammation taken out of Circulation (Research) for data manipulation

Circulation Research, a journal of the American Heart Association (AHA), has retracted a 2009 article from a German group whose first author copped to manipulating data — and got called on it. From the notice: Continue reading German paper on inflammation taken out of Circulation (Research) for data manipulation

Tangled leads: Cardiac study retraction reveals a company’s stopped trials, and lots of questions

A retraction in an obscure journal. An equally obscure retraction notice. An Israeli company with no web presence. Conflicts of interest involving authors and editors.

That’s what we’ve uncovered so far after noticing the other day that the American Journal of the Medical Sciences (AJMS) had retracted a May 2010 article by a group of Israeli heart doctors led by Arthur Shiyovich, of Barzilai Medical Center in Ashkelon.

The paper described promising results in a study of a new test for diagnosing coronary artery disease at the bedside by measuring aspects of a patient’s pulse at the fingertip.

As AJMS editor David Ploth told us, the approach had seemed “kind of innovative” to him, so he’d accepted the manuscript: “It seemed like it might have some applicability.”

Ploth was therefore surprised sometime later to receive a letter from the authors requesting that the journal retract their paper. According to the journal: Continue reading Tangled leads: Cardiac study retraction reveals a company’s stopped trials, and lots of questions