Category: basic life sciences retractions

Neuroscientist made up data in NIH grant applications, says ORI

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Paul Muchowski, via Gladstone Institute

Paul Muchowski, a neuroscience researcher at the Gladstone Institute of Neurological Disease in San Francisco, faked data in multiple grant applications, according to findings released today by the Office of Research Integrity (ORI).

In a funded NIH grant, R01 NS054753-06A1, and two submitted grant applications, R01 NS054753-06 and R01 NS047237-06, ORI says that Muchowski “knowingly and intentionally” committed “research misconduct by falsifying and fabricating data” as follows:

ORI sanctions former Texas Tech postdoc for falsification, fabrication, plagiarism

biomed chromatographyThe Office of Research Integrity (ORI) has sanctioned a former Texas Tech postdoc for using data that had actually been generated before he joined the lab in a paper as if it were new.

Shuang-Qing Zhang, according to today’s announcement by the ORI, “engaged in research misconduct by the falsification and fabrication of plagiarized data” in a paper he claimed to have written with his supervisor, Reza Mehvar, “Determination of dextra-methylprednisolone conjugate with glycine linker in rat plasma and liver by high-performance liquid chromatography and its application in pharmacokinetics,” first published online in Biomedical Chromatography in 2009. [see update at end of post]

The work was supported by the National Institute of General Medical Sciences (NIGMS), National Institutes of Health (NIH), grant R01 GM069869. The ORI found that Zhang had: Continue reading ORI sanctions former Texas Tech postdoc for falsification, fabrication, plagiarism

Scientists retract paper because they’re “not satisfied with the quality of some of the data”

antiox and redoxA group of smoking researchers — no, not scientists who are on fire; scientists who study the effects of tobacco smoke — has retracted a 2009 article after deciding that they were no longer “satisfied with the quality of the data.”

The paper, “Cigarette Smoke–induced Oxidative/Nitrosative Stress Impairs VEGF- and Fluid Shear Stress–Mediated Signaling in Endothelial Cells,” came from the lab of Irfan Rahman, a lung disease expert at the University of Rochester. It appeared online in 2009 in Antioxidants & Redox Signaling, which will be familiar to readers watching the case of Dipak Das. 

As the notice explains: Continue reading Scientists retract paper because they’re “not satisfied with the quality of some of the data”

Stem cell retraction leaves grad student in limbo, reveals tangled web of industry-academic ties

stem cells developmentA contested retraction in Stem Cells and Development has left the Queensland University of Technology (QUT) graduate student who fought for it in limbo, uncertain if he will earn his PhD. And many of those who didn’t want the paper retracted have a significant financial interest in a company whose work was promoted by the research — despite any lack of disclosure in the now-retracted paper.

Here’s the notice: Continue reading Stem cell retraction leaves grad student in limbo, reveals tangled web of industry-academic ties

ORI investigating work from Caltech lab as PNAS paper is retracted

pnas1219The U.S. Office of Research Integrity is investigating work done at a Caltech lab after researchers there couldn’t replicate it, and retracted a paper based on the findings.

Here’s the notice, which ran this week in the Proceedings of the National Academy of Sciences (PNAS): Continue reading ORI investigating work from Caltech lab as PNAS paper is retracted

RNA paper retracted for “carelessness in including some of the figures”

molcellbiochemHere at Retraction Watch, we’ve covered retractions for misconduct, journal errors, editorial system hacking and even no particular reason.

And that’s just in the last week.

However, we’ve identified a new reported reason: carelessness. A paper in Molecular and Cellular Biochemistry claimed to show how a tiny RNA causes fat cells to die.

Instead, the paper died.

Turned out that rather than describe previously published data, the authors say they inadvertently included a figure that had already appeared in another paper.

The retraction for “miR-598 induces replicative senescence in human adipose tissue-derived mesenchymal stem cells via silent information regulator 1,” reads, in full: Continue reading RNA paper retracted for “carelessness in including some of the figures”

Journal of Neuroscience retraction, typically opaque, from author with history of errors

jneuroscienceThe Journal of Neuroscience has retracted a 2011 paper by an international group of scientists, including the prominent Maryland researcher Ronald Dubner, but readers won’t know why.

As the notice “explains“: Continue reading Journal of Neuroscience retraction, typically opaque, from author with history of errors

“Serious errors” in figures prompt concerning Neuroscience retraction

neuroscience1212 coverNeuroscience has retracted a 2009 paper by a team of Korean sports researchers for what appear to be figure irregularities. But the journal’s handling of the case is puzzling and unhelpful.

The article, “Treadmill exercise improves cognitive function and facilitates nerve growth factor signaling by activating mitogen-activated protein kinase/extracellular signal-regulated kinase1/2 in the streptozotocin-induced diabetic rat hippocampus,” came out of Korea National Sport University, among others. It seemed to suggest that exercise could make diabetic rats smarter.

According to the retraction notice: Continue reading “Serious errors” in figures prompt concerning Neuroscience retraction

Odd: Retractions 18 and 19 for Dipak Das, and a new paper in the same journal, as if nothing were amiss

Dipak Das, the resveratrol researcher found guilty of more than 100 counts of misconduct by the University of Connecticut, has two more retractions for his resume. But that’s not the most interesting part of this post, so keep reading after the notices.

Both retractions appeared in the October 2012 issue of the Journal of Cellular and Molecular Medicine. Here’s the first notice: Continue reading Odd: Retractions 18 and 19 for Dipak Das, and a new paper in the same journal, as if nothing were amiss

Neuroscience paper retracted after HHMI investigation finds scientist copied images without permission

The Howard Hughes Medical Institute (HHMI) asked a journal to retract a paper once it became clear that some of the images in it were actually from a different HHMI lab.

Here’s the notice, from the Journal of Comparative Neurology: Continue reading Neuroscience paper retracted after HHMI investigation finds scientist copied images without permission