Leading cancer vaccines researcher retracts paper for figure “discrepancies” flagged by watchdog blog

Gerold Schuler, a German immunology researcher who shared the 2006 Deutscher Krebspreis — aka the German Cancer Prize — for his work that contributed to cancer vaccines has retracted a paper in International Immunology following concerns raised by a German science watchdog blog.

Here’s the notice: Continue reading Leading cancer vaccines researcher retracts paper for figure “discrepancies” flagged by watchdog blog

Whistleblower forces retractions of four stem cell papers amid questions about more than a dozen studies

In a case that is a good reminder of why journal editors shouldn’t ignore anonymous tips, a Seoul National University stem cell researcher has been forced to retract four papers, and withdraw another under peer review, in Antioxidants & Redox Signaling following a whistleblower’s exhaustive analysis.

Two retractions by Soo Kyung Kang, a professor of veterinary biotechnology at Seoul National University, appeared on May 9 after an anonymous whistleblower sent a 70-slide PowerPoint presentation to the editors of ten journals that contained evidence of suspicious floating error bars, errors larger than actual measurements, pasted-together lanes in PCR gels and RNA and CHIP blots and several cases where the same control blot data is shown across different experiments and in different papers. In all, the whistleblower raises questions about 14 papers in the ten journals.

Here is the May 9 notice for “Nuclear Ago2/HSP60 contributes to broad spectrum of hATSCs function via Oct4 regulation”: Continue reading Whistleblower forces retractions of four stem cell papers amid questions about more than a dozen studies

Journal retracts protein paper from scientist who misused deceased mentor’s data

It seemed like a touching tribute when Jiasheng Diao dedicated his 2009 article, “Crystal Structure of Butyrate Kinase 2 from Thermotoga maritima, a Member of the ASKHA Superfamily of Phosphotransferases,” in the Journal of Bacteriology to a deceased mentor, Miriam Hasson.

Before her death in January 2006, of a brain tumor, Hasson and her husband, David Sanders, made up a power-team of protein researchers at Purdue.

Hasson was an X-ray crystallographer while Sanders is a biochemist, and together they would map out the structure and function of proteins. One of their projects  was a  collaboration funded by a grant to Sanders from the National Science Foundation. By the time Diao joined, the effort had already led to butyrate-kinase crystals — albeit of poor quality, Sanders said.

When Hasson died, Sanders — with his institution’s blessing — took control of her data. That made sense, since their labs had collaborated closely. Indeed, they occasionally shared post-docs, including Diao, who had started with Hasson on a project looking at a protein called butyrate kinase but then moved over to Sanders’ lab as the work evolved. Continue reading Journal retracts protein paper from scientist who misused deceased mentor’s data

Retraction seven for Shouwei Han, this one in the American Journal of Physiology

ShouWei Han, who has been forced to retract six papers from various physiology journals following an investigation into his work by his former employer, the University of Louisville, has added another one to his tally.

Here’s the notice, from the American Journal of Physiology: Lung Cellular and Molecular Physiology: Continue reading Retraction seven for Shouwei Han, this one in the American Journal of Physiology

Correcting The Anatomical Record: Article pulled after former student lifted lab findings

The Anatomical Record, the official organ of the American Association of Anatomists, weighs its acceptances on “the quality of the research, its originality and significance to our readership.”

So it’s not surprising that when it gets duped, it gets angry.

Consider the following retraction notice that appeared recently in the publication for an article it ran early 2010: Continue reading Correcting The Anatomical Record: Article pulled after former student lifted lab findings

Assay come, assay go: Corporate takeover leads to retraction of device analysis

A group of hematology researchers in Canada lost a publication to the merger of two medical device makers, after the acquiring company apparently decided not to pursue marketing the product in question.

An April 23 retraction notice in the International Journal of Laboratory Hematology about the article, “Enhanced flagging and improved clinical sensitivity on the new DxH 300TM Coulter® cellular analysis system,” originally published in February, tells the tale: Continue reading Assay come, assay go: Corporate takeover leads to retraction of device analysis

Group investigated by University of Louisville corrects lung cancer paper after retracting six others

A group of researchers whose work has been under investigation at the University of Louisville has issued a correction for a paper in the American Journal of Respiratory Cell and Molecular Biology (AJRCMB).

The correction follows three retractions each in the Journal of Biological Chemistry and the AJRCMB, the latter of which made it clear that lab member ShouWei Han was responsible for the manipulations and duplications that brought down the papers. Here’s the new notice, which appeared in the March 1, 2012 issue of the journal: Continue reading Group investigated by University of Louisville corrects lung cancer paper after retracting six others

It’s all bad, it’s all good: JCI retracts for made-up data but authors stand behind work

The Journal of Clinical Investigation has retracted a 2010 article after the researchers acknowledged that the paper contained a substantial amount of manipulated or manufactured data.

How much bad data? Enough to sink seven figures. And the authors said they could not produce raw data in another 19 or so figures and four tables.

But, as the notice states, the researcher said that despite the retraction, they stand by the thrust of their article, “Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice:” Continue reading It’s all bad, it’s all good: JCI retracts for made-up data but authors stand behind work

Endocrinologist Shigeaki Kato resigns amidst University of Tokyo misconduct investigation

Shigeaki Kato

Shigeaki Kato, an endocrinology researcher at the University of Tokyo who retracted a paper late last month, has resigned amidst an investigation into whether he committed misconduct, Japanese media outlets are reporting.

According to the reports, the university has been investigating Shigeaki Kato and his group, affiliated with the Institute of Molecular and Cellular Biosciences, for scientific misconduct. The investigation was prompted by an outside whistleblower’s allegations in January about 24 of Kato’s papers. The whistleblower claimed that the papers manipulated and reused data improperly, and created a YouTube video to spread the word, as ScienceInsider reported earlier this year.

One of the 24 papers, Continue reading Endocrinologist Shigeaki Kato resigns amidst University of Tokyo misconduct investigation

Back in the saddle: After more than 30 retractions, Naoki Mori publishing again

Naoki Mori

Perhaps it’s appropriate given the Easter season, but we have learned that Naoki Mori, the Japanese cancer researcher who received a 10-year publishing ban from the American Society of Microbiology (ASM) for imagine manipulation, has published a new paper.

Mori, who was fired and then rehired by the University of the Ryukyus over the scandal, is listed as the senior author on the paper, “Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia,” which appears in the March issue of Biochimica et Biophysica Acta. The journal, an Elsevier title, is an umbrella for nine publications in the biosciences.

Two of Mori’s retracted articles appeared in the Elsevier journals Leukemia Research and Biochemical and Biophysical Research Communications. Continue reading Back in the saddle: After more than 30 retractions, Naoki Mori publishing again