Science plays two — a retraction, and concern issued about genetics papers

It’s a busy week at Science. The journal is retracting a controversial paper about which it had previously expressed doubts, and has published an “Expression of Concern” about another article that looks like it might be headed for the same fate.

First, the retraction.

The move involves an October 2009 paper, on which we’ve previously posted, by European researchers who claimed to have made a major advance in the ability to watch how enzymes behave in cells — thereby giving scientists a new tool for monitoring the function of genes.

But back in December, Science editor Bruce Alberts issued this “Expression of Concern” about the research: Continue reading Science plays two — a retraction, and concern issued about genetics papers

It’s poll time: Should a retraction during graduate school mean losing your PhD?

photo by secretlondon123 via flickr http://www.flickr.com/photos/secretlondon/

A few weeks ago, we reported on the case of Emily Horvath, a promising scientist at Indiana University who admitted to falsifying data to make her results look better. Some of that data went into her PhD thesis. That prompted a Retraction Watch reader to ask whether scientists who commit such fraud should be stripped of their PhDs. We figured that was a good poll question, so let us know what you think.

More on Ahluwalia et al Nature retraction, from Tom DeCoursey

Yesterday,we posted on the retraction of a 2004 Nature paper on innate immunity whose findings had been questioned by two groups. A few hours after we posted that item, we heard back from the senior author of one of the papers doubting that data, Tom DeCoursey. DeCoursey makes a number of important points, so we thought it would be a good idea to share them as a post: Continue reading More on Ahluwalia et al Nature retraction, from Tom DeCoursey

Previously questioned Nature paper on innate immunity retracted

courtesy Nature

Last week, we noted a Nature editorial in which the journal came clean about its higher-than-average number of retractions this year — four. What we missed was the fact that the fourth retraction of the year also appeared in last week’s issue.

The retraction, of a paper called “The large-conductance Ca2+-activated K+ channel is essential for innate immunity,” reads (link to the author’s homepage added): Continue reading Previously questioned Nature paper on innate immunity retracted

Cell pulls fruit fly article, citing image manipulation

The journal Cell has retracted a paper on fruit fly genetics over concerns that the first author, a postdoc in a German laboratory, might have manipulated dozens of electron micrographs in the manuscript.

The article, published in November 2009, was titled “Assembly of Endogenous oskar mRNA Particles for Motor-Dependent Transport in the Drosophila Oocyte.” It has been cited six times since then, according to the Thomson Scientific Web of Knowledge.

Not having the foggiest notion of what those words might mean, other than that the paper was about fruit flies, we called in a ringer, Jeff Perkel, who explained as patiently as he could that the gist of the research involved Continue reading Cell pulls fruit fly article, citing image manipulation

A retraction in the Potti case?

In our very first post, we noted the case of Anil Potti,

a Duke researcher who posed as a Rhodes Scholar and appears to have invented key statistical analyses in a study of how breast cancer responds to chemotherapy[.The case] has sent ripples of angst through the cancer community. Potti’s antics prompted editors of The Lancet Oncology to issue an “expression of concern” — a Britishism that might be better expressed as “Holy Shit!” — about the validity of a 2007 paper in their journal by Potti and others.

There hasn’t been any further movement on The Lancet Oncology study, as far as we know, but on Friday the Raleigh News & Observer reported that one of Potti’s co-authors on a 2007 Journal of Clinical Oncology (JCO) paper had requested a retraction: Continue reading A retraction in the Potti case?

Top German anesthesiologist’s cardiac surgery paper retracted over “very serious misrepresentations”

Self-plagiarism alert: A very similar version of this post is being published online in Anesthesiology News, where one of us (AM) is managing editor.

A leading German anesthesiologist with more than 200 papers to his name has been accused of misrepresenting critical aspects of a paper  — possibly including the data itself — published late last year in the journal Anesthesia & Analgesia.

In a retraction notice published online today, Steven L. Shafer, editor-in-chief of the journal, writes that Joachim Boldt and his coauthors failed to obtain approval from an institutional review board, did not get patient consent and did not follow up as promised with volunteers in their study, reported in the December 2009 article, “Cardiopulmonary Bypass Priming Using a High Dose of a Balanced Hydroxyethyl Starch Versus an Albumin-Based Priming System.”

In addition, the journal said, it has reason to suspect that data in the paper were fabricated, a possibility that is being investigated by German authorities. As the notice states: Continue reading Top German anesthesiologist’s cardiac surgery paper retracted over “very serious misrepresentations”

Warts and all: Derm pub retracts plantar paper after author cries foul

Both Retraction Watch bloggers are all too familiar with the artwork in dermatology journals. One of us, AM, used to write for Skin & Aging, while the other, IO, waited eagerly for issues of Cutis sent to his pediatrician father to show up on the coffee table. And IO recently broke the incredibly important story of “Mexican beer dermatitis.”

But we always trusted that the images we were looking at were real. A group of Egyptian dermatologists seems to have hit on a novel solution to the problem of uncooperative images: Continue reading Warts and all: Derm pub retracts plantar paper after author cries foul

Third retraction for Indiana University scientist who altered figures in NIH-funded research

Another shoe has dropped in the case of Emily M. Horvath, the Indiana researcher whose tinkering with figures while on a $369,000 federal grant ended in sanctions by government officials.

Biochemical and Biophysical Research Communications, an Elsevier title, has retracted another paper on which Horvath was an author, bringing to three the number of her articles tainted in the scandal. The paper, “A novel membrane-based anti-diabetic action of atorvastatin,” was published online in June 2008, and cited four times since, according to Thomson Scientific’s Web of Knowledge. (Atorvastatin is sold as Lipitor.) According to the journal: Continue reading Third retraction for Indiana University scientist who altered figures in NIH-funded research

They wuz robbed: Editorial TKO for boxing paper leads to retraction, republication

In the blue corner: California researchers who reviewed trends in death rates among professional boxers.

In the red (ink) corner: The editors of Neurosurgery, who misclassified the article, leading to an abbreviated version appearing in print.

The decision: A retraction, followed by a reclassification and republication of the complete article: Continue reading They wuz robbed: Editorial TKO for boxing paper leads to retraction, republication