Another retraction of Spirocor research

Remember Spirocor, the Israeli company that closed down a clinical trial involving its “respiratory stress” test for coronary artery disease because the data underpinning the validity of the method proved unreliable? The problem led to the retraction of two articles, about which we’ve previously reported. But we also found a study by some of the same researchers, who include scientists in Israel and the United States, that had been presented at the 2010 meeting of the American Heart Association and published in the journal Circulation.

That abstract, No. 14426 “Accuracy and Usefulness of Finger Pulse Wave Analysis during Brief Deep Breathing Exercise (Respiratory Stress Response) as a Marker of Significant Coronary Artery Disease,” has now been retracted — making, to our knowledge, the entire body of published research on the Spirocor product an editorial memory.

Here’s the notice, which appears within the text of the abstract: Continue reading Another retraction of Spirocor research

Sigh: “The purpose of keeping these retraction notices slim is not to produce too much detail”

Regular readers of this blog by now know that one of our goals is to make retractions as open and informative as possible. Which is why when they’re not, we get irritated that not everyone seems to agree.

Consider the editors of Computational and Theoretical Chemistry, which this month has retracted two papers from a group of researchers in Iran. The articles were titled “Determination of the electrode potentials for substituted 1,2-dihydroxybenzenes in aqueous solution: Theory and experiment” first published online in July 2006 and cited 25 times, according to the Thomson Scientific Web of Knowledge, and “Calculation of electrode potentials of 5-(1,3-dioxo-2-phenyl-indan-2-yl)-2,3-dihydroxy-benzoic acid, molecular structure and vibrational spectra: A combined experimental and computational study,” which appeared in December 2006. (Both articles were published in the journal’s previous incarnation as the Journal of  Molecular Structure: THEOCHEM.)

The reason given in each case  is the same — and tantalizingly cryptic: Continue reading Sigh: “The purpose of keeping these retraction notices slim is not to produce too much detail”

In a retraction’s wake: Postdoc Shane Mayack, dismissed from Amy Wagers’ stem cell lab, speaks out

 

Last October, Retraction Watch readers will recall, up-and-coming stem cell researcher Amy Wagers retracted a study in Nature describing how her team rejuvenated blood-forming stem cells in older mice. Shane Mayack, a postdoc in Wagers’ lab who had been dismissed after an inquiry into what happened, did not sign that retraction. Since then, Mayack has not spoken to the press, except for a brief comment to Nature through her attorney.

Here, we present, unedited, Mayack’s side of the story. While accepting responsibility, she also has a number of suggestions for how universities and journals can handle these situations better. Shane can be reached at smayck[at]yahoo.com.

Since it was well covered by this blog, the readers of Retraction Watch are no doubt aware that in October 2010, a paper that I co-authored was retracted from Nature and a notice of concern was posted regarding a second paper published in Blood.

So, what went wrong? Continue reading In a retraction’s wake: Postdoc Shane Mayack, dismissed from Amy Wagers’ stem cell lab, speaks out

As last of 12 promised Bulfone-Paus retractions appears, a (disappointing) report card on journal transparency

The final two retractions by Silvia Bulfone-Paus and colleagues, among the 12 promised by Research Centre Borstel following an investigation into scientific misconduct, have appeared. Both are in the Journal of Biological Chemistry (JBC), and read as follows:

This article has been withdrawn by the authors.

We find that near-complete lack of information frustrating, not to mention useless to the scientific community. Unfortunately, it’s par for the course when it comes to the JBC and Bulfone-Paus retractions. The other three said exactly the same thing.

With that in mind, we thought it would be worth looking at all 12 retraction notices, as a sort of case series in journals’ transparency. We often look at particular retractions in a vacuum, but here was a chance to look at 12 papers, all retracted for the same reason, to see how each journal reported the withdrawal.

Here are the 12, in rough order, worst to best, based on how useful they are to scientists coming across them: Continue reading As last of 12 promised Bulfone-Paus retractions appears, a (disappointing) report card on journal transparency

Aftermath: Gut-wrenching misstep leads to retraction, frayed feelings and a paperless postdoc

Graham Ellis-Davies says January 25th was one of the worst days of his life. That was when the journal ChemBioChem retracted an article, published barely two weeks earlier, for a mistake Ellis-Davies blames squarely on himself.

The fallout has been nearly two months of painful self-recrimination, a tattered friendship and, perhaps most significant, he adds, the wasted effort of a postdoc who poured months of research into a now worthless publication. Continue reading Aftermath: Gut-wrenching misstep leads to retraction, frayed feelings and a paperless postdoc

Tenth Bulfone-Paus retraction notice appears, in Journal of Biological Chemistry

The tenth of 12 promised retractions by Silvia Bulfone-Paus and colleagues has appeared, in the Journal of Biological Chemistry (JBC).

The paper, “Reverse signaling through membrane-bound Interleukin-15,” was published in 2004 and has been cited 31 times, according to Thomson Scientific’s Web of Knowledge. The retraction notice, just like the other one for the team’s work that appeared in the JBC, was completely uninformative: Continue reading Tenth Bulfone-Paus retraction notice appears, in Journal of Biological Chemistry

Joachim Boldt retraction tally drops by one, editors say (but record’s still safe)

As the news of Joachim Boldt’s staggering number of retractions leaps from Retraction Watch into the mainstream press, the consortium of journal editors retracting his studies has backtracked ever so slightly, announcing today that one of the 89 studies for which the German anesthesiologist lacked ethics approval in fact had such sanction.

According to the now-16 (Updated 3/7/11, as it is up from 11 several days ago) editors, LÄK-RLP,  the German body investigating the ethics component of the Boldt case: Continue reading Joachim Boldt retraction tally drops by one, editors say (but record’s still safe)

Plagiarism and other ‘negligence’ fell lung-estrogen paper

There’s parsing a-plenty in the American Journal of Physiology Lung Cellular and Molecular Physiology this month. The journal has retracted a 2010 paper by researchers at Chiba University in Japan, who lifted much of their manuscript from an article by other scientists in a different publication.

The authors of the paper, “The estrogen paradox in pulmonary arterial hypertension,” confess that they misappropriated text. But how they do so is a case study in subtlety: Continue reading Plagiarism and other ‘negligence’ fell lung-estrogen paper

Ladies and gentlemen, we have an apparent retraction record holder: Joachim Boldt, at 89

It’s official.* Joachim Boldt now holds the record for the most retractions by a single author.

As we reported the other day, a group of anesthesia journals was on the verge of revealing a list of 89 articles by Joachim Boldt that would require retraction because the German researcher had failed to receive proper approval from ethics officials for his studies. Today, the coalition issued a letter making the retractions official.

The 89 papers join an earlier retraction in October.

Of note: Continue reading Ladies and gentlemen, we have an apparent retraction record holder: Joachim Boldt, at 89

NEJM retracts Potti paper

courtesy Duke

About a month ago, the New England Journal of Medicine told us that they didn’t “have any plans” to retract a paper by Anil Potti. Apparently, they’ve changed their minds.

Today, they posted this retraction notice: Continue reading NEJM retracts Potti paper