Former Harvard dental school researcher committed misconduct: ORI

Martin Biosse-Duplan
Martin Biosse-Duplan

Last week was a busy one at the U.S. Office of Research Integrity (ORI), at least judging by how many cases they posted. There were sanctions against researchers at Ohio State, Texas Tech, and the Gladstone Institutes, as we reported. And it turns out there was another case closed, of a former Harvard dental school research fellow, The Scientist reports.

According to the ORI, Martin Biosse-Duplan “engaged in research misconduct in research supported by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), grant R01 AR054450.”

The misconduct involved a lab presentation and two published abstracts: Continue reading Former Harvard dental school researcher committed misconduct: ORI

Neuroscientist made up data in NIH grant applications, says ORI

muchowskip111
Paul Muchowski, via Gladstone Institute

Paul Muchowski, a neuroscience researcher at the Gladstone Institute of Neurological Disease in San Francisco, faked data in multiple grant applications, according to findings released today by the Office of Research Integrity (ORI).

In a funded NIH grant, R01 NS054753-06A1, and two submitted grant applications, R01 NS054753-06 and R01 NS047237-06, ORI says that Muchowski “knowingly and intentionally” committed “research misconduct by falsifying and fabricating data” as follows:

ORI sanctions former Texas Tech postdoc for falsification, fabrication, plagiarism

biomed chromatographyThe Office of Research Integrity (ORI) has sanctioned a former Texas Tech postdoc for using data that had actually been generated before he joined the lab in a paper as if it were new.

Shuang-Qing Zhang, according to today’s announcement by the ORI, “engaged in research misconduct by the falsification and fabrication of plagiarized data” in a paper he claimed to have written with his supervisor, Reza Mehvar, “Determination of dextra-methylprednisolone conjugate with glycine linker in rat plasma and liver by high-performance liquid chromatography and its application in pharmacokinetics,” first published online in Biomedical Chromatography in 2009. [see update at end of post]

The work was supported by the National Institute of General Medical Sciences (NIGMS), National Institutes of Health (NIH), grant R01 GM069869. The ORI found that Zhang had: Continue reading ORI sanctions former Texas Tech postdoc for falsification, fabrication, plagiarism

ORI: Ohio State researcher manipulated two dozen figures in NIH grants, papers

terry elton
Terry Elton, via OSU

Terry S. Elton, a researcher at Ohio State University in Columbus who studies genetic expression in various heart conditions and Down syndrome, has been sanctioned by the U.S. Office of Research Integrity for fabricating and/or falsifying data in a number of NIH grants and resulting papers.

According to an OSU statement sent to Retraction Watch last night, it was an anonymous whistleblower who alerted the university to the potential misconduct in July 2010. The ORI report notes that he two OSU investigations, along with the ORI investigation, found that Elton: Continue reading ORI: Ohio State researcher manipulated two dozen figures in NIH grants, papers

ORI investigating work from Caltech lab as PNAS paper is retracted

pnas1219The U.S. Office of Research Integrity is investigating work done at a Caltech lab after researchers there couldn’t replicate it, and retracted a paper based on the findings.

Here’s the notice, which ran this week in the Proceedings of the National Academy of Sciences (PNAS): Continue reading ORI investigating work from Caltech lab as PNAS paper is retracted

ORI sanctions former University of Kentucky nutrition researcher for faking dozens of images in 10 papers

Eric J. Smart, via U Kentucky

The U.S. Office of Research Integrity has come down hard on a Eric J. Smart, an NIH-funded former University of Kentucky nutrition researcher who faked data in ten published papers and seven grant applications over the past decade.

Smart studies cholesterol, heart disease, diabetes, and high blood pressure. According to the notice in the Federal Register: Continue reading ORI sanctions former University of Kentucky nutrition researcher for faking dozens of images in 10 papers

ORI investigating University of Florida ob-gyn researcher accused of misconduct

A prominent researcher at the University of Florida is under federal investigation for research misconduct and has lost at least one paper as a result of the fraud.

The researcher, Nasser Chegini, was a professor of obstetrics and gynecology at the U of Florida until about six months ago, when he retired, according to the chair’s office. Nasser has received at least $4 million in federal grant funding, according to the university.

The retracted paper, “MicroRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells,” was published in 2010 by Molecular Human Reproduction. The authors were Qun Pan and Xiaoping Luo and Chegini.

As the notice explains: Continue reading ORI investigating University of Florida ob-gyn researcher accused of misconduct

ORI findings lead to two retractions — nearly 17 years later

Well, it only took 17 years.

As two retraction notices in the September 15 issue of the Journal of Immunology note:

On October 19, 1995, the Office of Research Integrity at the National Institutes of Health found that Weishu Y. Weiser, Ph.D., formerly of the Harvard Medical School at Brigham and Women’s Hospital, committed scientific misconduct by falsifying data in biomedical research supported by two Public Health Service grants. As a result, she agreed to submit a letter to The Journal of Immunology to retract this article. The offices of The Journal of Immunology have no record of receiving such a letter and hence the article is now being retracted.

The retractions, for “Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” and “Human Recombinant Migration Inhibitory Factor Activates Human Macrophages to Kill Leishmania donovani,” both say the same thing.

“Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” has been  cited 66 times, according to Thomson Scientific’s Web of Knowledge — 40 of those times since the ORI’s report was released. The numbers for the Leishmania paper are almost identical: Continue reading ORI findings lead to two retractions — nearly 17 years later

Former Harvard psychology prof Marc Hauser committed misconduct in four NIH grants: ORI

Two years after questions surfaced about work by former Harvard psychology professor Marc Hauser, an official government report is finally out.

It’s not pretty.

The findings by the Office of Research Integrity were first reported by the Boston Globe, which was also first to report the issues in Hauser’s work. They’re extensive, covering misconduct in four different NIH grants (we’ve added some links for context): Continue reading Former Harvard psychology prof Marc Hauser committed misconduct in four NIH grants: ORI

ORI finds Harvard stem cell lab post-doc Mayack manipulated images

courtesy Nature

Shane Mayack, a former post-doc in Harvard lab of Amy Wagers, a rising star in the stem cell field, has been sanctioned by the Office of Research Integrity for misconduct.

Mayack, who has defended her actions on this blog as honest error — albeit sloppiness — and has not admitted to wrongdoing, must undergo supervision if she receives any federal grant funding over the next three years, under the voluntary agreement.

Here’s the notice, which appeared in the Federal Register this week (and which the Boston Globe was first to report): Continue reading ORI finds Harvard stem cell lab post-doc Mayack manipulated images