Category: misconduct investigations

Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

Paolo Macchiarini
Paolo Macchiarini

Following an investigation, Karolinska Institutet has found that surgeon and visiting professor Paolo Macchiarini acted in some cases “without due care,” but that his behavior “does not qualify as scientific misconduct.”

Karolinska’s Vice Chancellor has also recommended that Macchiarini submit an unspecified number of corrections “to clarify and rectify the failings that the inquiry has brought to light.”

Macchiarini is most well-known for pioneering the creation of tracheas from cadavers and patients’ own stem cells. However, the glow of his success was diminished somewhat after four Karolinska surgeons filed a complaint, alleging Macchiarini had downplayed the risks of the procedure and not obtained proper consent, among other accusations.

An external review by Bengt Gerdin of Uppsala University concluded in May that Continue reading Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

Three retractions for Oregon neuroscience student investigated by ORI

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Journals have retracted three out of the four papers flagged by the Office of Research Integrity during its investigation of a University of Oregon neuroscience student, David Anderson.

Last month, when we first reported on the case, Anderson told us that he “made an error in judgment,” and took “full responsibility.” Two of the retraction notes say that Anderson “knowingly falsified data,” and cited the Office of Research Integrity case summary.

All three papers focus on memory.

The note for the first retraction, from the  Journal of Experimental Psychology: Human Perception and Performance, reveals exactly how Anderson falsified data in the paper. It’s paywalled — tsk, tsk — but printed here in full:
Continue reading Three retractions for Oregon neuroscience student investigated by ORI

Researchers suspended in Japan for funding violations

Sanae Ariga
Sanae Ariga

Hokkaido University has suspended two of its professors after an investigation found “improper receipt of research funding.”

One member of the team was awarded more than 15 million yen (roughly $120,000 USD) in research grants from the Japan Society for the Promotion of Science (JSPS), according to the official statement (translated by One Hour Translation).

The researchers share a last name. Hiroyoshi Ariga, a professor of Biomedical and Pharmaceutical Science and the head of a university lab, was given 8 million yen in 2006 and 7.5 million in 2007. It appears that Sanae Ariga also received funds for a similar study, based on the translation:

Continue reading Researchers suspended in Japan for funding violations

Diederik Stapel ups count to 55 retractions

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Diederik Stapel

Dutch social psychologist and well-known fraudster Diederik Stapel is up to 55 retractions. He remains secure in his spot at #4 on our leaderboard.

The “fraudulent” Social Cognition article found, according to its abstract, that the more positively you perceive yourself, the less you need to compare yourself to other people. Conversely, negative thoughts were linked to more comparison to others. As an article in the New York Times points out, where Stapel’s faulty studies often succeeded is in telling us what we want to believe about the world.

Here’s the retraction note for the article:

Continue reading Diederik Stapel ups count to 55 retractions

Journal that published bogus chocolate study delisted from open access directory

logo_croppedThe journal that recently published a bogus study showing the health benefits of chocolate has been kicked out of a membership organization for open access journals.

According to the Directory of Open Access Journals (DOAJ), the International Archives of Medicine was removed from the list of member journals August 20, due to “suspected editorial misconduct by publisher.”

The journal is still was listed in PubMed until November 2014.

According to the DOAJ website, membership to the organization serves as a stamp of approval for OA journals:

Continue reading Journal that published bogus chocolate study delisted from open access directory

Former Wake Forest grad student fudged data for drug study

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Brandi Blaylock

A former graduate student at Wake Forest School of Medicine “presented falsified and/or fabricated data” in a government-funded drug study, according to findings released by the U.S. Office of Research Integrity earlier today.

The report was released in the wake of an investigation conducted by the university and the ORI. Investigators found that although Brandi Blaylock recorded responses of a dozen laboratory monkeys after giving them anti-abuse drugs, she hadn’t given them the compounds “per protocol.”

Blaylock then presented the data at “two poster presentations, several laboratory meetings, and progress reports.”

Some of her research was supported by a grant from the National Institute of Drug Abuse, “Dopamine D2 Receptors In Primate Models of Cocaine Abuse,” which examined the effects of novel dopamine D3 receptor compounds on drug addiction on monkeys.

However, according to the report, Blaylock presented the falsified responses from a dozen monkeys: Continue reading Former Wake Forest grad student fudged data for drug study

Trouble with data proves toxic for a pair of toxicology papers

logoA pair of papers about the risks of titanium dioxide nanoparticles that share many of the same authors has been retracted from a toxicology journal following an investigation at Soochow University in China.

Particle and Fibre Toxicology is retracting the papers for problems with the statistical methods and missing data, as well as for sharing figures.

Here’s the note for “Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications:”

Continue reading Trouble with data proves toxic for a pair of toxicology papers

8 things you might not know about research misconduct proceedings: Guest post

Callan Stein

Have you ever wondered what could happen if you’re accused of misconduct and face official proceedings? We are pleased to present a guest post from Callan Stein, a lawyer who represents U.S. researchers in misconduct cases, who describes some nuances many may not realize about these situations. 

Most researchers know that being accused of research misconduct is a very serious matter. When research misconduct allegations are made, institutions embark upon lengthy, multi-staged inquiry and investigation processes as required by federal law. The federal government’s Office of Research Integrity (“ORI”) – part of the Department of Health and Human Services (HHS) – oversees those institutional findings and imposes potentially career-threatening punishments on those found guilty. While researchers generally understand the basics of how a research misconduct case unfolds, many are unaware of the nuances that bear greatly on the outcome.  What follows are brief descriptions of eight such nuances of which every researcher should be aware.

  1. While “honest error” exempts researchers from misconduct, it is very hard to prove.

Continue reading 8 things you might not know about research misconduct proceedings: Guest post

Three more retractions for former record-holder Boldt, maybe more to come

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Justus Liebig University in Germany has been investigating concerns that Joachim Boldt, number two on the Retraction Watch Leaderboard and now up to 92 retractions, may have “manipulated” more data than previously believed.

Until now, the vast majority of Boldt’s retractions were thought to have involved inadequate ethics approval. However, new retraction notices for Boldt’s research suggest that there’s evidence the researcher also engaged in significant data manipulation.

The first retraction from the university investigation emerged last year. Two of three new notices cite the investigation specifically, and an informant at the university told us that there are more retractions to come.

Here are the retracted papers that are freshly on the record, starting with an August retraction for a 1991 Anesthesiology paper (cited 37 times, according to Thomson Scientific’s Web of Knowledge):

Continue reading Three more retractions for former record-holder Boldt, maybe more to come

Drugmaker accused of omitting side effect data from 2003 Risperdal paper

cover7607A 2003 paper may have left out potentially “significant” data on the long-term side-effects of an antipsychotic drug used in children, according to a former head of the U.S. Food and Drug Administration.

As reported by the Toronto Star, David Kessler is alleging that Janssen, the maker of Risperdal (and owned by Johnson & Johnson), omitted data about the risks of the drug: In particular, that boys who use it over a long period may be at risk of growing breasts.

There’s anecdotal evidence of the side effect. One family claimed the drug had caused their son to grow a pair of 46 DD-sized breasts in a lawsuit against Johnson & Johnson, reported the Wall Street Journal in February. They won, to the tune of $2.5 million. The suit is apparently just one of 1,200 like it.

The abstract of the paper, “Prolactin levels during long-term risperidone treatment in children and adolescents,” published in The Journal of Clinical Psychiatry, suggests that levels of a key hormone aren’t a problem in the long term:

Continue reading Drugmaker accused of omitting side effect data from 2003 Risperdal paper