Fifth Alirio Melendez retraction offers clues about University of Glasgow misconduct findings

A new retraction — his fifth — in the Journal of Immunology for Alirio Melendez, formerly of the National University of Singapore, the University of Glasgow, and the University of Liverpool, sheds some light on the results of an investigation by one of the universities.

Last month, a Glasgow spokesperson told Nature that the university’s investigation had been completed in October 2011, but that it did not comment on individual cases. A spokesperson, according to the Times Higher Education:

…would say only that there was “no evidence that our current staff contributed, falsified or duplicated data to any publications co-authored with (Professor) Melendez”. He also confirmed that relevant journals would be contacted where retractions or corrections were deemed necessary.

The notice for one such necessary retraction, in the September 15 issue of the Journal of Immunology, gives a few details: Continue reading Fifth Alirio Melendez retraction offers clues about University of Glasgow misconduct findings

Retraction count for Dipak Das rises to 17

We have four more retractions by Dipak Das, the disgraced UConn researcher found by the university to have committed 145 counts of misconduct. All appear in the Journal of Molecular and Cellular Cardiology (we left the journal off when we initially posted, as commenters noted):

Redox regulation of angiotensin II preconditioning of the myocardium requires MAP kinase signaling,” cited 28 times, according to Thomson Scientific’s Web of Knowledge:
Continue reading Retraction count for Dipak Das rises to 17

Glasgow’s Beatson Institute investigating circumstances of Cell retraction for inappropriate images

The Beatson Institute for Cancer Research in Glasgow, Scotland is looking into how inappropriate images ended up in a Cell paper that has just been retracted.

Here’s the notice for the paper by Lynne Marshall, Niall S. Kenneth, and Robert J. White: Continue reading Glasgow’s Beatson Institute investigating circumstances of Cell retraction for inappropriate images

University College London mitochondrial biologist resigns after three retractions for image fraud

Courtesy Nature Publishing Group

A biologist at University College London (UCL) has resigned his post and taken responsibility for “inappropriate figures manipulations” in three now-retracted papers.

Assegid Garedew, formerly a senior research investigator in Salvador Moncada‘s group, stepped down earlier this summer in the midst of an investigation that should be completed soon, Moncada tells Retraction Watch.

The three retraction notices for papers by Garedew and colleagues are all similar.

From Cell Metabolism: “Mitochondrial Dynamics, Biogenesis, and Function Are Coordinated with the Cell Cycle by APC/CCDH1“, cited once, according to Thomson Scientific’s Web of Knowledge: Continue reading University College London mitochondrial biologist resigns after three retractions for image fraud

ORI finds Harvard stem cell lab post-doc Mayack manipulated images

courtesy Nature

Shane Mayack, a former post-doc in Harvard lab of Amy Wagers, a rising star in the stem cell field, has been sanctioned by the Office of Research Integrity for misconduct.

Mayack, who has defended her actions on this blog as honest error — albeit sloppiness — and has not admitted to wrongdoing, must undergo supervision if she receives any federal grant funding over the next three years, under the voluntary agreement.

Here’s the notice, which appeared in the Federal Register this week (and which the Boston Globe was first to report): Continue reading ORI finds Harvard stem cell lab post-doc Mayack manipulated images

A Wnt-er’s tale: Blood pulls second signaling paper from Spanish scientists over image fakery

Blood has pulled a paper 2007 paper from a group of Spanish researchers, one of whom appears to have been manipulating images.

The group’s work became the focus of expressions of concern from the Journal of Clinical Oncology this spring and in 2010.

The article, “Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia,” purported to show “a role of abnormal Wnt signaling in ALL and establish a group of patients with a significantly worse prognosis (methylated group)” and earned a commentary on the significance of the findings.

But as the notice explains, the first author lifted and manipulated a figure from a previously published article: Continue reading A Wnt-er’s tale: Blood pulls second signaling paper from Spanish scientists over image fakery

Authors retract prostate cancer-grape seed compound paper for figure presentation error

University of Alabama researchers have retracted a paper claiming that a grape skin seed compound might have anti-prostate cancer effects.

Here’s the notice for “Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NFκB”: Continue reading Authors retract prostate cancer-grape seed compound paper for figure presentation error

Seeing red (wine): Another retraction for Dipak Das, making count 13

Today’s Retraction Watch, to paraphrase Sesame Street, is brought to you by the number 13.

Earlier, we reported on several retractions from Diederik Stapel that bring his total to that number, and now we’ve learned about number 13 for Dipak Das. Das is of course the UConn researcher who was found to have committed 145 counts of misconduct in his studies of the red wine compound resveratrol and other subjects.

Here’s the notice, from The Journal of Nutritional Biochemistry, for “Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose:” Continue reading Seeing red (wine): Another retraction for Dipak Das, making count 13

Retraction number four appears in PNAS for work of Alirio Melendez, who has resigned post at U Liverpool

Alirio Melendez, who has had three of his papers retracted amidst suspicions about 70, has had another one retracted, this one in the Proceedings of the National Academy of Sciences (PNAS). And he has also resigned from his post at the University of Liverpool, we have just learned.

Here’s the notice: Continue reading Retraction number four appears in PNAS for work of Alirio Melendez, who has resigned post at U Liverpool

A correction for Alirio Melendez, in Journal of Cellular Physiology

We’ve been covering the case of Alirio Melendez, three of whose papers have been retracted amidst questions about almost 70 studies. The latest development is a correction in the Journal of Cellular Physiology, which has already retracted one of his papers, of a study on which he was a co-author.

Here’s the correction for “Short dysfunctional telomeres impair the repair of arsenite-induced oxidative damage in mouse cells”: Continue reading A correction for Alirio Melendez, in Journal of Cellular Physiology