Category: biomedcentral

“A painful lesson:” Authors retract paper after discovering mislabeled mouse lines

Neuroscientists have retracted a 2016 paper examining the genetic underpinnings of a degenerative motor neuron disease, after discovering that two mouse lines had been accidentally mislabeled.

According to the retraction notice, published in December in Acta Neuropathologica Communications, mice engineered to have a specific genetic mutation were mislabeled as the normal or wild type group.

The notice cites an investigation by the University of Florida; we asked the university for a copy of the report. The university sent us a redacted document, which a spokesperson told us was a self-report from the researchers regarding the mislabeling. The spokesperson explained: Continue reading “A painful lesson:” Authors retract paper after discovering mislabeled mouse lines

Caught Our Notice: Journals still (slowly) purging archives of bad cell line studies

Via Wikimedia

Title: Tanshinone IIA Induces Apoptosis in Human Oral Cancer KB Cells through a Mitochondria-Dependent Pathway

What Caught Our Attention: Thousands of papers have relied on contaminated or wrong cell lines, a problem journals have not been particularly proactive in addressing. So far, only a few studies have been retracted for using misidentified cell lines. Continue reading Caught Our Notice: Journals still (slowly) purging archives of bad cell line studies

Ethical concerns arise for head of controversial stem cell clinic

Geeta Shroff. Photo credit: Nutech Mediworld

Journals are raising ethical concerns about the research of a doctor who offers controversial embryonic stem cell treatments.

Two journals have issued expressions of concern for three papers by Geeta Shroff, who was the subject of a 2012 CNN investigative documentary. All cite ethical concerns; one mentions the potential link between the procedure the authors describe and a risk of forming teratomas, a type of tumor. Shroff has objected to all three notices.

Shroff, a doctor offering controversial embryonic stem cell treatments at her New Delhi clinic, Nutech Mediworld, has said that for years she couldn’t find opportunities to present her research to the medical community. Continue reading Ethical concerns arise for head of controversial stem cell clinic

Another retraction hits high-profile food researcher under fire

Brian Wansink

It’s been a rough year for Brian Wansink.

Last year, the prominent food researcher posted a blog praising a student for her productivity in his lab. But when Wansink described his methods, readers became concerned that the lab was using improper research techniques to generate more publications. Earlier this year, researchers posted an analysis of four papers by Wansink about pizza consumption to PeerJ, saying they discovered more than 150 inconsistencies in the data. Now, one of those four papers has been retracted.

On Friday, BMC Nutrition posted a brief notice about the 2015 paper, which examined whether people who pay different amounts for all-you-can-eat Italian buffets feel more or less guilty about how much they ate. The notice says the retraction stems from concerns about the data analysis, and the authors do not agree with the journal’s decision.

The new retraction is the second for Wansink, director of the Food and Brand Lab at Cornell.

Here’s the complete retraction notice:

Continue reading Another retraction hits high-profile food researcher under fire

Fertility docs said their study didn’t need ethics review. An investigation said they were wrong.

Arcispedale Santa Maria Nuova-IRCCS. Credit: IRCCS-ASMN

A journal is retracting a paper on the relative merits of one fertility procedure compared to another because the study never received ethical review or approval.

In the paper, “Intracytoplasmic morphologically selected sperm injection versus conventional intracytoplasmic sperm injection: a randomized controlled trial,” originally published Aug. 27, 2015 in Reproductive Biology and Endocrinology, the authors wrote: Continue reading Fertility docs said their study didn’t need ethics review. An investigation said they were wrong.

Researchers retract a paper when they realize they had sequenced the wrong snail’s genome

Researchers in China thought they had sequenced the genomes of two snails that help transmit diseases to other species — an important first step to stopping the spread. But their hopes were soon dashed after they realized they had misidentified one of the snails.

The researchers published their findings earlier this year in the journal Parasites & Vectors. In the paper, the authors stressed that understanding the genetic makeup of these molluscs is important because many “freshwater snails are intermediate hosts for flatworm parasites and transmit infectious diseases” to humans and other animals. They also acknowledged that identifying snail species from their appearance alone can be tricky. Continue reading Researchers retract a paper when they realize they had sequenced the wrong snail’s genome

Journal retracts paper it says authors published twice. Authors disagree.

A journal has retracted a 2012 paper after determining that the authors had already published it elsewhere.

According to the retraction notice, the editors-in-chief of the Journal of Occupational Medicine and Toxicology concluded that the article had  been published in another journal—In Vitro Cellular & Developmental Biology – Animal—the previous month. The authors, however, did not agree to the retraction.

The research, led by Ali Khavanin, who is based at Tarbiat Modares University in Tehran, Iran and is corresponding author on both papers, evaluated whether the vibrations from industrial machinery can harm hearing in rabbits (1, 2).

Here’s the retraction notice for “Assessment of the influence of whole body vibration on Cochlear function”: Continue reading Journal retracts paper it says authors published twice. Authors disagree.

How much text recycling is okay?

Are there a limited number of ways to describe the the background and methods of an experiment? Once something has been written well, and vetted by editors, is it a waste of time to rewrite it ? And if text has been reused, how should that be indicated — if at all?

These are questions we’ve asked before — and are revisiting after reviewing a pair of commentaries published earlier this year in Research Integrity and Peer Review. We’ve certainly seen our fair share of retractions due to duplication (so many we can’t cover them all) — but in one commentary, Cary Moskovitz — the Director of Writing in the Disciplines at the Thompson Writing Program at Duke University — argues that some text recycling — aka, “self-plagiarism” or duplication — is sometimes unavoidable, and, in some situations, even preferable. He told us:

Continue reading How much text recycling is okay?

Author of retracted gene editing paper alleges “bullying” by former PI

In the fall of 2015, out-of-work stem cell biologist Mavi Camarasa decided she had waited long enough. It had been three years since she and a colleague were, best they could tell, the first to successfully correct the most common cystic fibrosis mutation in stem cells derived from a patient.

But her former lab director, Daniel Bachiller, had blocked her from writing even a short report, she told Retraction Watch:

He said we are not submitting at this time, wait until [the project is] complete. “Wait, wait,” is the only answer I’d had from him ever.

Though she’d left the Spanish regenerative medicine lab in 2013 to take care of an ailing parent and had mostly been scooped by another group in April of that year, Camarasa thought she still might be able to get something out of the project. She hatched a plan to make him an offer he couldn’t refuse — an already accepted manuscript where all he would have to do is attach his name at the last minute.

But this story didn’t turn out exactly how she’d hoped — and illustrates how the pressure to publish can affect researchers at different levels in the lab.

Continue reading Author of retracted gene editing paper alleges “bullying” by former PI

NIH neuroscientist up to 16 retractions

Stanley Rapoport. Source: NIH

Neuroscientist Stanley Rapoport just can’t catch a break.

Rapoport, who’s based at National Institute on Aging, is continuing to experience fallout from his research collaborations, after multiple co-authors have been found to have committed misconduct.

Most recently, Rapoport has had four papers retracted in three journals, citing falsified data in a range of figures. Although the notices do not specify how the data falsification occurred, Jagadeesh Rao, who was recently found guilty of research misconduct, is corresponding author on all four papers.

Back in December, Rapoport told us that a “number of retractions [for] Rao are still in the works:” Continue reading NIH neuroscientist up to 16 retractions