Paper used to support WHO guidelines on preventing infections “has no scientific validity”

A surgery journal retracted a 2014 paper last month after discovering that the study has “no scientific validity.”

Mario Schietroma and his coauthors, based at the University of LAquila in Italy, reported that giving patients high concentrations of oxygen during and after colorectal surgery significantly reduced their risk of infections. Although the authors reported significant p-values, the retraction notice states that, “upon recalculation, no p-values were close to significant.” The University of LAquila told Retraction Watch it is investigating, but did not provide details. Continue reading Paper used to support WHO guidelines on preventing infections “has no scientific validity”

Author: “The retractions were about bureaucracy, not science”

A researcher has retracted two 2014 papers, after discovering they had not gone through the proper approval process before being submitted.

The papers were part of a collaboration funded by the U.S. National Institutes of Health, which focused on solving protein structures. Adam Godzik, the senior author, told Retraction Watch that all papers had to be approved by a special committee before being submitted to a journal. Given the scale of the collaboration, the committee for the Joint Center for Structural Genomics (JCSG) would assess whether researchers who had made a previous contribution to the work should be added as authors.

Proteins: Structure, Function, and Bioinformatics retracted both papers after Godzik informed the editor in August 2014 that neither article had undergone the required review before being submitted to the journal. Although Wiley agreed to the retractions in an email to Godzik in September 2014,  the papers were only pulled in January—more than three years later. Continue reading Author: “The retractions were about bureaucracy, not science”

Caught Our Notice: “The first author cut the thermoprinter paper printout into pieces and reassembled them”

Title: A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins

What Caught Our Attention: Here’s a cut-and-paste issue that gave us pause. The authors of an 18-year-old paper in PNAS corrected it after realizing some bands in a figure were duplicated (an issue raised on PubPeer one year ago). It turns out, the first author had cut the paper into pieces and reassembled them to present the blots in the “desired order,” and some had become duplicated by mistake. The overall results were unaffected, so the journal swapped the image with a corrected version. Continue reading Caught Our Notice: “The first author cut the thermoprinter paper printout into pieces and reassembled them”

Figures in cancer paper at root of newly failed compound called into question

How much role did a potentially problematic paper play in the demise of a once-promising compound?

Researchers are questioning the validity of a high-profile article, published by Nature in 2006. Although the letter is 12 years old, the concerns have current implications: It was among the early evidence used to develop a cancer compound that recently failed a number of clinical trials.

It’s unclear whether the problems with the paper — if validated — could have contributed to the compound’s demise. But an outside expert has some thoughts — and so do image experts and multiple external reports, including one released this month, which agree the concerns about the figures have merit. (The first author’s ex-husband isn’t too happy with the article, either.)

Continue reading Figures in cancer paper at root of newly failed compound called into question

Management researcher admits to falsification, resigns

David DeGeest

A business journal has retracted two papers after the corresponding author admitted he falsified his results.

David DeGeest, an assistant professor in the Department of Management and Marketing, has also resigned from The Hong Kong Polytechnic University, a university spokesperson told Retraction Watch.

Last month, DeGeest confessed to the Journal of Management (JOM) that he had falsified the results in two papers in the journalone from 2015 and one from 2016.

The papers explored strategies startups can use to increase their odds of survival. The 2015 work was highlighted in the Wall Street Journal, among other outlets; one story in Business News Daily is no longer on the site.

David Allen, the editor-in-chief of the journal, told us: Continue reading Management researcher admits to falsification, resigns

Caught Our Notice: Former rising star loses fourth paper

Title: Haemophilus influenzae responds to glucocorticoids used in asthma therapy by modulation of biofilm formation and antibiotic resistance

What Caught Our Attention: This is the fourth retraction for Robert Ryan, formerly a high-profile researcher studying infections that can be deadly in people with lung diseases such as cystic fibrosis. In 2016, the University of Dundee in Scotland determined that Ryan had committed research misconduct, including misrepresenting clinical data and duplicating images in a dozen different publications. (Ryan tried to appeal the decision, then resigned.) The latest retraction cites a few problems with the paper, including uncertainty about the provenance of some data.

According to the notice, the second-to-last author, George A. O’Toole at Dartmouth, disagrees with the text of the notice, not the decision to retract. We contacted O’Toole, who declined to comment.

We received a statement from Ryan about the retraction:

Continue reading Caught Our Notice: Former rising star loses fourth paper

UCSF-VA investigation finds misconduct in highly cited PNAS paper

PNAS has corrected a highly cited paper after an investigation found evidence of misconduct.

The investigationconducted jointly by the University of California, San Francisco, and the San Francisco Veterans Administration Medical Centeruncovered image manipulation in Figure 2D, which “could only have occurred intentionally.” The institutions, however, could not definitively attribute the research misconduct to any individual.

According to the notice, the UCSF-VA committee determined that a correction to the 2008 PNAS paperwhich explores the genetic underpinnings of prostate cancerwas “appropriate,” and the authors have now replaced the problematic figure with a corrected version. The 2008 paper has been cited 630 times, according to Clarivate Analytics’ Web of Science.

A spokesperson for PNAS told Retraction Watch: Continue reading UCSF-VA investigation finds misconduct in highly cited PNAS paper

Over a dozen editorial board members resigned when a journal refused to retract a paper. Today, it’s retracted.

Following a massive editorial protest, Scientific Reports is admitting its handling of a disputed paper was “insufficient and inadequate,” and has agreed to retract it.

The 2016 paper was initially corrected by the journal, after a researcher at Johns Hopkins University, Michael Beer, accused it of lifting some of his earlier work. After we covered the story, nearly two dozen Hopkins researchers threatened to resign from the journal’s editorial board if the journal didn’t retract the paper — and many followed through with that threat after the journal reaffirmed its initial decision. In response, the journal said it would assemble a “senior editorial committee” to review its decision-making.

That committee, it appears, has determined that the journal erred in its initial decision. According to a statement from the journal provided to Retraction Watch:

Continue reading Over a dozen editorial board members resigned when a journal refused to retract a paper. Today, it’s retracted.

Caught Our Notice: Retraction eight as errors in Wansink paper are “too voluminous” for a correction

Title: Shifts in the Enjoyment of Healthy and Unhealthy Behaviors Affect Short- and Long-Term Postbariatric Weight Loss

What Caught Our Attention: Cornell food marketing researcher Brian Wansink, the one-time media darling who has been dogged by mounting criticism of his findings, has lost another paper to retraction. As we’ve noted in the past, corrections for Wansink’s work tend to be long. This time, “the number of errors is too voluminous to be executed by issuing a correction statement,” according to the retraction notice for a paper about behaviors following weight loss surgery. Continue reading Caught Our Notice: Retraction eight as errors in Wansink paper are “too voluminous” for a correction

“Clear signs of manipulation” in paper co-authored by prominent geneticist

David Latchman

A third paper co-authored by researchers based at a prominent lab whose work has been under investigation on and off for almost three years has been retracted.

According to the notice, the university’s investigation found that a 2008 paper in FEBS Letters contained “clear signs of manipulation” in three figures.

Research from geneticist David Latchman’s group has been dogged by misconduct allegations since late 2013 and subject to two investigations by the University College London (UCL). Continue reading “Clear signs of manipulation” in paper co-authored by prominent geneticist