Category: by journal

“Dramatic impact:” Authors misread breast cancer treatment database, retract paper

A journal has retracted a 2016 study on the use of radiation by breast cancer patients after the authors misinterpreted what was reported in a national cancer database.

Correcting for the error, according to the retraction notice, had a “dramatic impact on the original article data and conclusions.”

Quyen Chu, a surgeon at Louisiana State University Health Shreveport, told us that the problem appears to stem from a misunderstanding about the US National Cancer Database (NCDB). After the paper was published, the NCDB pointed out to Chu that a key data point had not been reliably or consistently collected during the timeframe relevant to the study. The database’s user’s manual says essentially the same thing; Chu said he and his authors read it, but misunderstood it.

The original Journal of the American College of Surgeons study looked at whether a 2004 National Comprehensive Cancer Network treatment guideline — which suggested some patients could avoid radiation on top of surgery and hormone therapy — led to an actual decrease in radiation therapy. But the error forced the authors to drop tens of thousands of patients treated before 2004, which had a severe impact on their ability to draw conclusions.

Chu told us:

Continue reading “Dramatic impact:” Authors misread breast cancer treatment database, retract paper

Paper by Harvard cancer biologist flagged over “credible concerns”

A cancer biologist at Harvard who’s issued multiple editorial notices in recent years has received an expression of concern about a 2011 paper, citing “credible concerns” with the data and conclusions.

The publisher does not detail the nature of the issues in the notice.

In the past few years, last author Sam W. Lee lost a Molecular Cell paper in 2013 due to figure duplication and a Journal of Biological Chemistry paper in 2015, citing “manipulated” data in a figure.

Lee also issued two mega-corrections in 2011 in Nature and Current Biology, which also cited figure duplication. Interestingly, both papers were corrected for a second time — the 2006 Current Biology paper in 2016, over figure-related errors, and the 2011 Nature paper in 2015, over concerns the animals used may have experienced excess suffering (prompting an editorial from the journal).

The latest notice, issued by the Journal of Biological Chemistry, doesn’t provide much information for the basis of its expression of concern over Lee’s 2011 paper: Continue reading Paper by Harvard cancer biologist flagged over “credible concerns”

Despite author’s protest, journal removes paper on emergency department prices

A journal has temporarily removed a paper showing the dramatic differences in the cost of providing emergency care that caught national attention (and some criticism from emergency care providers), despite the first author’s claims that the results are valid.

The paper, published online in February by the Annals of Emergency Medicine, showed that it can cost significantly more for patients to be treated at emergency departments than at urgent care centers, even for the same conditions. Soon after the paper was published, first author Vivian Ho at Rice University was told by the American College of Emergency Physicians, which publishes the journal, that there were some errors in the appendix, and they wanted to reanalyze the entire paper.

Ho told us:

Continue reading Despite author’s protest, journal removes paper on emergency department prices

Former UCLA vice-chancellor loses cancer paper for image manipulation

The former vice chancellor for research at the University of California, Los Angeles, has retracted a 2012 paper after an internal investigation found evidence of image manipulation.

The journal Molecular Cancer Therapeutics received a letter about the problems with the paper from the UCLA Research Integrity Officer, and a retraction request from last author James Economou, also the chief of surgical oncology.

According to the notice, the paper duplicated images from a 2011 paper also by first author Ali Jazirehi, based at UCLA. This is Jazirehi’s second retraction.

Here’s more from the notice:

Continue reading Former UCLA vice-chancellor loses cancer paper for image manipulation

Can we do math unconsciously? Replicators of a prominent 2012 study have some doubts

In 2012, news media were abuzz with a new finding from PNAS: Authors based in Israel had found evidence that our brains can unconsciously process more than we thought — including basic math and reading.  In other words, the authors claimed people could read and do math without even knowing what they were doing.

With such a major development in the field of consciousness research, other groups quickly got to work trying to replicate the findings. Those efforts have taken some twists and turns — including a recent retraction of a replication paper that was, itself, not reproducible (which is not something we see every day). But overall, five years after the initial, remarkable result, the replication efforts are calling it into question.

According to Pieter Moors at KU Leuven, a researcher in this field:

Continue reading Can we do math unconsciously? Replicators of a prominent 2012 study have some doubts

After researcher is convicted of sexual assault, journal retracts her co-author’s paper

A disability journal has retracted a paper supposedly penned by a man with severe disabilities, citing duplication.

Although the reason for the retraction may sound run-of-the-mill, this situation is far from ordinary.

The author, known as DMan Johnson — or simply “D.J.” — has cerebral palsy, and was communicating using a controversial technique called “facilitated communication” with Anna Stubblefield, the former chairwoman of philosophy at Rutgers University. In October 2015, Stubblefield was convicted of sexually assaulting D.J., who has been diagnosed with spastic quadriplegia and severe mental retardation. The following month, she was sentenced to 12 years in prison.

In October 2015, Disability Studies Quarterly issued a statement that it was taking a second look at papers by Stubblefield, but did not specify which ones.

Continue reading After researcher is convicted of sexual assault, journal retracts her co-author’s paper

Updated: Science fish-microplastics paper retracted

Despite continuing to vigorously defend their work, the authors of a controversial paper about the effects of human pollution asked Science to retract the paper last week.

According to a release from Uppsala University issued today, authors Peter Eklöv and Oona Lönnstedt submitted their request to Science last week, noting they wanted to withdraw the paper “as long as a suspicion of misconduct remains.”

The release — which echoes a statement that was also provided to Nature — notes:

Continue reading Updated: Science fish-microplastics paper retracted

Researcher who sued to prevent retractions now has 12

A diabetes researcher who once sued a publisher to prevent several retractions has just issued his 12th.

The latest retraction, like several others for Mario Saad, appears in the journal Diabetes. Although in the past Saad expended considerable effort to protect four other Diabetes papers from this same fate, the latest retraction was initiated by the authors, citing several duplicated images. The American Diabetes Association had flagged the 2009 paper with an expression of concern earlier this year.

In 2015, Saad brought a lawsuit against the ADA, claiming that it “wrongfully published” four expressions of concerns in its flagship journal Diabetes, in an attempt to prevent the papers from being retracted. He lost, and the papers were retracted in 2016.

The lawsuit also did nothing to deter the ADA from flagging other potentially problematic papers with expressions of concerns, including the latest 2009 Diabetes paper, on which Saad is last and corresponding author.  Continue reading Researcher who sued to prevent retractions now has 12

PLOS upgrades flag on controversial PACE chronic fatigue syndrome trial; authors “surprised”

PLOS ONE has issued an expression of concern after the authors of a controversial study about chronic fatigue syndrome declined to share some of their data.

In an unusual move, the journal included the authors’ response to the expression of concern (EOC), in which they strongly argue against the notice, and “do not accept that it is justified.”

In 2015, following public requests to review the data, the journal issued an “editor’s note” on the paper, noting the journal’s policy that authors make data and materials available.

There have been numerous requests for data from the “PACE” trial, as the clinical trial is known. Patients and advocates have long disputed the results, arguing that suggesting cognitive behavior and graded exercise therapy could cause harm.

In the latest notice, the journal says it consulted two editorial board members about the paper, a 2012 sub analysis of a controversial clinical trial on chronic fatigue syndrome. The journal then asked the authors to provide the data behind five tables, which would enable researchers to replicate the cost-effectiveness analyses the authors report for different therapies — including graded exercise therapy, which some patient advocates believe could be harmful.

As with previous requests for data, the authors refused to provide it, citing patient confidentiality and consent. The notice explains:

Continue reading PLOS upgrades flag on controversial PACE chronic fatigue syndrome trial; authors “surprised”

Author objects to retraction after he says journal ignored his queries for three years

In 2014, a journal contacted researcher Denis Rousseau about one of his papers that had just been published online ahead of print, raising some concerns. According to Rousseau, he sent the journal a corrected figure “almost immediately,” which he believed addressed the issue.

Rousseau, a cell biologist at the University Joseph Fourier in Grenoble, France, said he then contacted the journal many times over the next three years to ask about the status of the paper — which never ended up in print — but heard nothing back.

Three years passed.

In March, the publisher finally contacted Rousseau, this time to ask him to issue a formal retraction for the paper. And despite his objections, Molecular and Cellular Biology published a sparse retraction notice, which provides little information about what went wrong:

Continue reading Author objects to retraction after he says journal ignored his queries for three years