Other shoe drops for MIT cancer researcher Robert Weinberg as Cell retraction appears

cell cloningRobert Weinberg, a prominent cancer scientist whose papers often notch hundreds or thousands of citations, has lost a fourth paper, this time a 2009 publication in Cell.

Journal Genes and Development pulled two of Weinberg’s papers in March, stating that they had retracted the 2009 study because data from several experiments was used in figures that seemed to represent only one. The Genes and Development papers were sunk because the “same analytical methodology was used.”

At the time, the Cell retraction was unavailable, though a spokesperson informed us it was forthcoming. The paper has been cited 482 times, according to Thomson Scientific’s Web of Knowledge.

Now that the notice has landed, here’s why the paper is being retracted: Continue reading Other shoe drops for MIT cancer researcher Robert Weinberg as Cell retraction appears

Major methods error prompts retraction of lung radiation paper

nmmiOne of the authors of a 2014 case series on lung disease following radiation in Nuclear Medicine and Molecular Imaging is retracting the paper for what the the journal is calling “honest error.” That may be true, but it’s a big error — so big, it’s amazing no one detected it sooner.

The paper was titled “A Case Series of Four Patients With Clinically Significant Radiomicrosphere Pneumonitis After Yttrium-90 Radioembolization from the Perspective of Lung Dosimetry,” and it came from a group in Singapore and Australia.

According to the retraction notice: Continue reading Major methods error prompts retraction of lung radiation paper

Concurrent submission and publication squashes nano paper

CoverIssueJExptNanoSciA group of materials researchers at Solapur University in India have lost a paper because they submitted an identical manuscript to two journals. Both journals published the paper, though only one has retracted it.

Taylor and Francis journal Journal of Experimental Nanoscience retracted the 2012 paper in February this year; the notice doesn’t explain the delay, or how the editors learned about the overlap.

The retraction indicates the editor of the journal that published the other version of the paper was informed of the overlap, but the journal — – Journals of Materials Science: Materials in Electronics — has not issued a retraction.

Here’s the notice for “Development of nanostructured CdS sensor for H2S recognition: structural and physical characterizations”: Continue reading Concurrent submission and publication squashes nano paper

Retraction and republication for Lancet Resp Med tracheostomy paper

lancetrmA paper whose expression of concern we covered in November 2014 has been retracted and republished “because of the extent of the changes necessary,” according to the Lancet Respiratory Medicine.

This isn’t the first time we’ve seen retraction/republications at the Lancetaccompanied by thorough breakdowns of the problem.

This study was a meta-analysis of research on how the timing of tracheostomies — placing a breathing tube directly into the windpipe — affects patients’ mortality rate. The original paper found that critically ill patients who received a tracheostomy earlier fared better than those for whom the procedure was delayed for weeks after intubation, the recommended practice.

However, when the authors calculated how many patients died, they assumed that any patient who wasn’t discharged from the intensive care unit (ICU) had died there, instead of looking for other explanations. This made their estimates unreliable.

The publisher convened a panel, which ultimately decided retraction and republication was the most appropriate course of action.

The original expression of concern contained a quote from the authors about the “data discrepancy” that would later sink the paper: Continue reading Retraction and republication for Lancet Resp Med tracheostomy paper

You can’t make this stuff up: Plagiarism guideline paper retracted for…plagiarism

ijdermThis could be an April Fools’ joke. But it isn’t.

In what can only be described as an ironic twist, the Indian Journal of Dermatology is retracting a paper that presents guidelines on plagiarism for…wait for it…

Plagiarism.

Here’s the notice: Continue reading You can’t make this stuff up: Plagiarism guideline paper retracted for…plagiarism

Slippery slope? Data problems force retraction of landslide paper

The Mameyes Landslide, in Puerto Rico, buried more than 100 homes in 1985.  Source: USGS
The Mameyes Landslide, in Puerto Rico, buried more than 100 homes in 1985. Source: USGS

The authors of a 2014 paper in The Scientific World Journal on rock slopes have retracted their article for “erroneous” data.

The paper, “Slope Stability Analysis Using Limit Equilibrium Method in Nonlinear Criterion,” came from a group of researchers from institutions including the Changjiang River Scientific Research Institute in Wuhan, and the Key Laboratory of Transportation Tunnel Engineering at Southwest Jiaotong University in Chengdu. It’s about (we think) how to calculate the safety of rock slopes, and how vulnerable they are to landslides.

Here’s the notice, which as a pretty fair ratio of words to information:

Continue reading Slippery slope? Data problems force retraction of landslide paper

Journal retracts part of molecular bio paper due to “unsubstantiated conclusions”

j mol evAll but one of the authors of a 2013 Journal of Molecular Evolution paper have requested a partial retraction due to “erroneous data” and “scientific misconduct” on the part of the remaining author.

The note blames second author Michael Kolesnikov for falsifying data on the formation of ATP. According to the notice, the misconduct was confirmed by a “thorough investigation” by the Bach Institute of Biochemistry in Russia, which no longer employs Kolesnikov.

Here is the note for “Abiotic Photophosphorylation Model Based on Abiogenic Flavin and Pteridine Pigments”: Continue reading Journal retracts part of molecular bio paper due to “unsubstantiated conclusions”

Cancer Cell issues big correction over “incorrectly cropped” figures, other issues

cancer cell A 2014 Cancer Cell paper became the subject of an erratum in January 2015, shortly after PubPeer members began criticizing the data. However, many issues brought up by commenters weren’t addressed in the correction notice, including a figure that might be two experiments spliced together to look like one.

The paper, led by Guido Franzoso at Imperial College London, claims that a new cancer drug called DTP3 kills myeloma cells “without causing any toxic side effects,” according to a press release from the school. Guido Franzoso is the founder of Kesios Therapeutics, a drug company which is set to begin clinical trials on DTP3.

The correction indicates that Western blots were cropped badly, which omitted several panels discussed in the text, while an “extra time point” was included accidentally. An antibody was also omitted from the description of the procedure.

PubPeer commenters have noticed additional issues, such as a criticism of figure 3D, which were not included or changed in this correction.

Here’s the correction for “Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors”: Continue reading Cancer Cell issues big correction over “incorrectly cropped” figures, other issues

“Serious and obvious mistakes” kill paper on heart attacks in rats

j card pharmA group of researchers in China and the United States have retracted a 2014 paper in the Journal of Cardiovascular Pharmacology after discovering the data were fatally flawed.

The article examined whether the anti-arrhythmia drug zacopride affected cardiac remodeling after heart attack, and came from Bo-We Wu, of Shanxi Medical University, in Taiyuan, and colleagues, including one author from Savannah, Georgia.

Here’s more from the notice for “Activation of IK1 channel by zacopride attenuates left ventricular remodeling in rats with myocardial infarction”:

Continue reading “Serious and obvious mistakes” kill paper on heart attacks in rats

Drug paper gets a fix, notching several corrections

rsc_tb_1_3_COVER.inddThe Journal of Materials Chemistry B has issued a laundry list of corrections for a 2014 chemotherapy paper, which address re-use of “some text”, incorrectly stated doses, and miscalculations of the drug concentration, among other issues.

The paper described a new way to deliver gemcitabine via nanoparticles, focusing the drug on the tumors.

It turns out the authors’ focus wasn’t so clear when writing the paper. The researchers, at the Chinese Academy of Medical Science, Peking Union Medical College, and Tianjin University in China, said they used “some text” from two 2013 papers by a team of French oncologists “without appropriate attribution,” as well as repeatedly getting the in vivo dose wrong. The manuscript also contained several incorrect calculations of the “drug loading,” or the proportion of active drug.

Here’s the correction for “Tailor-made gemcitabine prodrug nanoparticles from well-defined drug–polymer amphiphiles prepared by controlled living radical polymerization for cancer chemotherapy” (free, but requires sign-in): Continue reading Drug paper gets a fix, notching several corrections