COPD paper in JCI retracted following PubPeer critiques

jciA 2011 paper in the Journal of Clinical Investigation whose PubPeer entry we highlighted in September has been retracted.

Here’s the notice for “Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients,” a 2011 paper by researchers at Johns Hopkins and Imperial College: Continue reading COPD paper in JCI retracted following PubPeer critiques

Cardiology researcher who admitted to fraud earns four-year funding ban

dfg_logoA researcher who admitted in 2012 to “intentional and systematic manipulation” of data and had two papers retracted has been banned from funding by the German Research Foundation (DFG).

Dennis Rottländer, who will also be returning prize money he was awarded for the research, worked in Uta C. Hoppe’s lab at the University of Cologne. Hoppe, now at University Hospital Salzburg, remains under investigation, according to a statement from the DFG.

Excerpt: Continue reading Cardiology researcher who admitted to fraud earns four-year funding ban

JCI retracts 10-year-old cancer study because figures were “intentionally mislabeled”

jci june 14The Journal of Clinical Investigation is retracting a 2004 paper by a cancer researchers from Italy because of “evident misrepresentation of data and image duplication.”

Here’s the notice for “The IL-12Rβ2 gene functions as a tumor suppressor in human B cell malignancies:” Continue reading JCI retracts 10-year-old cancer study because figures were “intentionally mislabeled”

Retraction appears for Italian cancer specialist facing criminal investigation

jci nov 13The first retraction has appeared for Alfred Fusco, a leading cancer researcher in Italy under criminal investigation for fraud.

Here’s the notice from the Journal of Clinical Investigation: Continue reading Retraction appears for Italian cancer specialist facing criminal investigation

Two patch-clamping retractions in PNAS and the JCI after first author admits image manipulation

jci1212A group of cardiology researchers formerly of the University of Cologne has retracted two papers, after investigations into allegations of misconduct led to an admission of guilt by one of the lab’s junior members.

Here’s the first retraction, for “Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial KATP channels in mouse cardiomyocytes,” published last week in the Journal of Clinical Investigation: Continue reading Two patch-clamping retractions in PNAS and the JCI after first author admits image manipulation

Two new corrections for Utah group that retracted two Cell Metabolism papers for missing notebooks

We have an update on the case of a University of Utah lab that retracted two Cell Metabolism papers last month after a fired lab technician disposed of two lab notebooks without permission. The team has now corrected two other papers, one in Blood and the other in the Journal of Clinical Investigation.

Here’s the notice from Blood: Continue reading Two new corrections for Utah group that retracted two Cell Metabolism papers for missing notebooks

It’s all bad, it’s all good: JCI retracts for made-up data but authors stand behind work

The Journal of Clinical Investigation has retracted a 2010 article after the researchers acknowledged that the paper contained a substantial amount of manipulated or manufactured data.

How much bad data? Enough to sink seven figures. And the authors said they could not produce raw data in another 19 or so figures and four tables.

But, as the notice states, the researcher said that despite the retraction, they stand by the thrust of their article, “Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice:” Continue reading It’s all bad, it’s all good: JCI retracts for made-up data but authors stand behind work

University of Perugia researcher faces trial for embezzlement, fraud following 13 retractions and Expressions of Concern

Stefano Fiorucci, a gastroenterology researcher at the University of Perugia in Italy, has been indicted for fraud and embezzlement, after a university investigation found that he had manipulated images in papers that he used to win about 2 million Euros in grant funding.

The case, which has so far resulted in four retractions and nine Expressions of Concern, has dragged on for several years. The trial is scheduled for July. It’s the first time that embezzlement charges have been brought against a scientist found to have committed fraud, according to reports in Umbria 24 and the Umbria Journal.

Fiorucci’s attorney, Stefano Bagianti, told Umbria 24 that there was Continue reading University of Perugia researcher faces trial for embezzlement, fraud following 13 retractions and Expressions of Concern