Former Harvard psychology prof Marc Hauser committed misconduct in four NIH grants: ORI

Two years after questions surfaced about work by former Harvard psychology professor Marc Hauser, an official government report is finally out.

It’s not pretty.

The findings by the Office of Research Integrity were first reported by the Boston Globe, which was also first to report the issues in Hauser’s work. They’re extensive, covering misconduct in four different NIH grants (we’ve added some links for context): Continue reading Former Harvard psychology prof Marc Hauser committed misconduct in four NIH grants: ORI

ORI finds Harvard stem cell lab post-doc Mayack manipulated images

courtesy Nature

Shane Mayack, a former post-doc in Harvard lab of Amy Wagers, a rising star in the stem cell field, has been sanctioned by the Office of Research Integrity for misconduct.

Mayack, who has defended her actions on this blog as honest error — albeit sloppiness — and has not admitted to wrongdoing, must undergo supervision if she receives any federal grant funding over the next three years, under the voluntary agreement.

Here’s the notice, which appeared in the Federal Register this week (and which the Boston Globe was first to report): Continue reading ORI finds Harvard stem cell lab post-doc Mayack manipulated images

Society error leads to published — then retracted — Alzheimer’s abstract from top group

Alzheimer’s & Dementia has retracted a meeting abstract the journal published without the OK of the researchers, a top group from Harvard, who submitted it but withdrew the work before the conference.

That, as they say, might require some unpacking. Maybe this will make things clearer.

Raj Hooli, a graduate student in the lab of Rudolph Tanzi, a leading neuroscientist at Harvard — where he holds the Joseph P. and Rose F. Kennedy endowed chair of neurology — had submitted the abstract, “Genome-wide assessment of copy number variations in early-onset Alzheimer’s disease,” for consideration at the International Conference on Alzheimer’s Disease (ICAD).

As Tanzi explains: Continue reading Society error leads to published — then retracted — Alzheimer’s abstract from top group

JAMA awaiting final OHRP decision on Harvard-led paper whose authors didn’t fully disclose risks to elderly

Earlier this month, the U.S. Office for Human Research Protections (OHRP) told a group of researchers led by a Harvard Medical School professor that they hadn’t been forthcoming enough about the risks elderly subjects faced in their trial.

As the Boston Globe reported: Continue reading JAMA awaiting final OHRP decision on Harvard-led paper whose authors didn’t fully disclose risks to elderly

Three AHA journals retract lipid papers over “negligent” record-keeping, image issues and more

Three journals belonging to the American Heart Association are dealing with a data manipulation case involving a Japanese scientist who collaborated with some of the United States’ most prominent  cardiac specialists.

Circulation has retracted a 2008 article after the researchers said the lead author’s sloppy record-keeping prevented them from reproducing their experiments. We think there might be a bit more to the story.

Here’s the notice: Continue reading Three AHA journals retract lipid papers over “negligent” record-keeping, image issues and more

Cell runs a lengthy correction, rather than retraction, for image problems

The journal Cell has an interesting — and somewhat puzzling — correction this month that we’ll add to our “mega-correction” file.

At issue is a paper, published in October, from the lab of Harvard’s Stephen Elledge, a noted genetics researcher, whose first author is a post-doc there named Michael Emanuele.

According to the notice, Emanuele (singled out, we note) seems to have been rather careless with the images used in the article, titled “Global Identification of Modular Cullin-RING Ligase Substrates”: Continue reading Cell runs a lengthy correction, rather than retraction, for image problems

Blood retracts stem cell paper from Amy Wagers’ Harvard lab after 14 months of concern

More than 14 months after Blood issued a notice of concern about a paper by a Harvard stem cell scientist and her former post-doc, the journal has retracted the article.

Here’s the notice for the paper, “Osteolineage niche cells initiate hematopoietic stem cell mobilization,” by Shane Mayack and Amy Wagers: Continue reading Blood retracts stem cell paper from Amy Wagers’ Harvard lab after 14 months of concern

Publisher error handling two eye papers leads to retractions, new policy on notices

We can only imagine how Joe Hollyfield felt to learn from us, of all people, that his journal, Experimental Eye Research, had retracted two manuscripts in a recent issue.

The papers, “Mechanisms of retinal ganglion cell injury and defense in glaucoma,” by Qu J, Wang D, and Grosskreutz CL, and “Mitochondria: Their role in ganglion cell death and survival in primary open angle glaucoma,” by Osborne, NN, carried the same retraction notices:

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

Because in our experience such unhelpful wording often masks interesting details — read, author misconduct — we called Hollyfield for comment. He graciously walked us through the retractions, explaining the case in detail, until we realized that we were talking about different papers entirely. Hollyfield, it turned out, thought we were asking about the travails of Sangiliyandi Gurunathan, an eye researcher from India whom we’d previously covered and whose work recently had been retracted by Experimental Eye Research and other journals for image manipulation.

But Hollyfield was unaware of the two retractions we’d intended to talk about with him and told us he’d look into them.

Here’s what he learned: Continue reading Publisher error handling two eye papers leads to retractions, new policy on notices

Marc Hauser resigns from Harvard

Marc Hauser, the Harvard psychology professor who retracted a paper last year following a university investigation, has resigned his post. As the Boston Globe’s Carolyn Johnson, who broke the original Hauser retraction story, reports: Continue reading Marc Hauser resigns from Harvard

Second retraction by Harvard group studying cannabinoids, this one in JBC

Last week, we reported that a group of Harvard researchers had retracted a paper in Blood for “multiple instances of duplicate (redundant) publication of data, text, and images that are nonessential to the paper.” The retraction notice referred to a paper in the Journal of Biological Chemistry (JBC):

The redundancies are between the above-cited Blood article and the following 12 November 2010 article, published in the Journal of Biological Chemistry (JBC): Jiang S, Zagozdzon R, Jorda MA, et al. Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. J Biol Chem. 2010;285(46):35471-35478.

Today, we learned that the JBC paper has also been retracted. The notice, as we’ve come to expect from the JBC, is unhelpful: Continue reading Second retraction by Harvard group studying cannabinoids, this one in JBC