A PNAS expression of concern appears — and so does its revealing backstory

pnas 1113When retraction notices and expressions of concern appear, particularly those that are opaque, we try our best to find out what’s behind them, whether it’s better explanations or the steps that led to moves. Today, we have one story in which we’ve been able to learn a lot more than usual.

In April, Bas van Steensel, Wendy Bickmore, Thomas Cremer, and Kerstin Bystricky sent a letter to about 80 leading labs in nuclear organization and steroid receptor biology. It began (we’ve added some relevant links): Continue reading A PNAS expression of concern appears — and so does its revealing backstory

Dissertation in transition: Plagiarism leads to delisting of education thesis, lost PhD

ccjThe author of a doctoral dissertation on veterans education has lost the paper — and a mention of the work in a roster of theses — because he lifted text from a previously published dissertation from a student at another institution.

Here’s the notice: Continue reading Dissertation in transition: Plagiarism leads to delisting of education thesis, lost PhD

Fudged figures sink breast cancer paper

oncogeneA prestigious cancer journal has pulled an article over “concerns” regarding some of the figures, which PubPeer commenters had tagged as suspect.

A few weeks after the paper was published on June 9, comments on PubPeer began accumulating. Commenters called out both potentially manipulated and repeated images. The exact timeline is not clear, because Oncogene does not list a date on the retraction notice, but by August 29 the paper had been retracted.

Here’s the notice for “IL-6 secreted by cancer-associated fibroblasts induces tamoxifen resistance in luminal breast cancer,” by researchers at Shanghai Jiaotong University School of Medicine and Ruijin Hospital, both in Shanghai, China, and the University of Michigan: Continue reading Fudged figures sink breast cancer paper

87% of bugs resistant to antibiotics? Not so fast, as staph paper yanked after staff mistake

What could have been a truly scary study about drug resistant staph infections in hospitals has been retracted due to a lab error.

6.coverResearchers at a community hospital in Pittsburgh claimed that the commonly quoted 3% rate of staph that is resistant to ceftriaxone and sensitive to methicillin was drastically understated. However, an “honest error in the interpretation of a key lab test” called the findings into question.

Here’s the abstract: Continue reading 87% of bugs resistant to antibiotics? Not so fast, as staph paper yanked after staff mistake

Tonic-clonic stats error sinks epilepsy paper

pm_cover_dez_01A brain imaging study in children with epilepsy has been retracted by the Journal of Magnetic Resonance Imaging due to a statistics error.

Here’s the notice for “Microstructural Brain Abnormalities of Children of Idiopathic Generalized Epilepsy With Generalized Tonic-Clonic Seizure: A Voxel-Based Diffusional Kurtosis Imaging Study”: Continue reading Tonic-clonic stats error sinks epilepsy paper

First author blamed for retraction in prestigious medical journal

jemcoverThe authors of a Journal of Experimental Medicine have retracted it, blaming the first author for data and figure manipulation.

The paper, “The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells,” was initially published in September 2011 and has been cited 25 times, according to Thomson Scientific’s Web of Knowledge. First author Jiyeon Kim was an MD-PhD candidate at the University of Pennsylvania until this year, according to a LinkedIn profile.

Here’s the notice: Continue reading First author blamed for retraction in prestigious medical journal

Cancer researcher has correction upgraded to retraction

mol endo coverRakesh Kumar, a researcher with six recent corrections and one retraction, has had one of those corrections upgraded to a retraction.

Here’s the unhelpful notice, from Molecular Endocrinology: Continue reading Cancer researcher has correction upgraded to retraction

Journal takes down autism-vaccine paper pending investigation

translational neurodegenerationAn article purporting to find that black children are at substantially increased risk for autism after early exposure to the measles-mumps-rubella vaccine has been shelved.

Although we don’t know if the events are related, the move comes amid claims that a CDC whistleblower has accused health officials of suppressing information about the link.

Not surprisingly, the prospect that the CDC has been sitting on evidence of an autism-vaccine connection for more than a decade has inflamed the community of activists wrongly convinced that such a link exists.

The paper, “Measles-mumps-rubella vaccination timing and autism among young african american boys: a reanalysis of CDC data,” was written by Brian Hooker, an engineer-turned-biologist and an active member of that community. It was submitted in April, accepted on August 5, and published on August 8.

Translational Neurodegeneration, which published the article earlier this month, has now removed it and posted the following notice: Continue reading Journal takes down autism-vaccine paper pending investigation

“Our jaws hit the floor!!” Researchers say authors doctored images for rebuttal letter

eurourologyTry to follow along on this one. We think it’s worth it.

The authors of a letter replying to a comment in a urology journal have retracted their response because it contained inappropriate figures. At least, that’s the official story.

The original paper, “Effect of a Risk-stratified Grade of Nerve-sparing Technique on Early Return of Continence After Robot-assisted Laparoscopic Radical Prostatectomy,” came from a group at Weill Medical College of Cornell University led by Ashutosh Tewari. Published in July 2012 in European Urology, it purported to find that: Continue reading “Our jaws hit the floor!!” Researchers say authors doctored images for rebuttal letter

New method sinks newish paper…or does it?

cover_2009_BB_viz_biomassThe timing on a recent retraction of a paper from Biotechnology and Bioengineering makes it a bit difficult to figure out what happened, but here’s a try.

An article first published online May 16th by a group of researchers at Brown University was retracted on June 1st, apparently because a new and better method for analyzing the data was developed…at some point.

The timeline is not exactly clear from the retraction, though we’ve reached out to the author and publisher and will update with any new information.

Here’s the (paywalled) notice for “High-level production of 3-hydroxypropionatein Escherichia coli and Saccharomyces cerevisiae by introducing part of the 3-hydroxypropionate/4-hydroxybutyrate cycle from Metallosphaera sedula”:

Continue reading New method sinks newish paper…or does it?