Category: united states

Retraction of grizzly bear-diabetes study follows departure of Amgen scientist for data manipulation

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The retracted paper made the cover of the August 2014 issue of the journal.

A study that looked to hibernating bears to understand the mechanisms behind diabetes has been retracted because an author based at the biotech company Amgen “manipulated specific experimental data” in two figures.

According to the The Wall Street Journal, Amgen discovered the manipulation while reviewing the data following publication of the paper,”Grizzly bears exhibit augmented insulin sensitivity while obese prior to a reversible insulin resistance during hibernation.” Published in Cell Metabolism last year, the paper has been cited 8 times, according to Thomson Scientific’s Web of Knowledge.

A press release from the journal last year — coverage in Science and Nature followed — explained the purpose of the study:

Continue reading Retraction of grizzly bear-diabetes study follows departure of Amgen scientist for data manipulation

Updated: Author resigns from West Point following paper legitimizing attacks on scholars who question terror tactics

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[Note: This post has been updated with new information about the author’s resignation.]

Following criticisms of a 2015 paper which proposed attacks on scholars who question the government’s handling of the war on terror, the author has resigned from his post at the U.S. Military Academy at West Point, New York.

The nearly 200-page paper, “Trahison des Professeurs: The Critical Law of Armed Conflict Academy as an Islamist Fifth Column,” appeared in the National Security Law Journal of George Mason University School of Law, in Virginia. It was written by William C. Bradford, who is a somewhat controversial figure.

In the paper, Bradford, assistant professor at the United States Military Academy, criticizes U.S. academics who specialize in armed conflict and claim “that the Islamist jihad is a response to valid grievances against U.S. foreign policy”: Continue reading Updated: Author resigns from West Point following paper legitimizing attacks on scholars who question terror tactics

Three retractions for Oregon neuroscience student investigated by ORI

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Journals have retracted three out of the four papers flagged by the Office of Research Integrity during its investigation of a University of Oregon neuroscience student, David Anderson.

Last month, when we first reported on the case, Anderson told us that he “made an error in judgment,” and took “full responsibility.” Two of the retraction notes say that Anderson “knowingly falsified data,” and cited the Office of Research Integrity case summary.

All three papers focus on memory.

The note for the first retraction, from the  Journal of Experimental Psychology: Human Perception and Performance, reveals exactly how Anderson falsified data in the paper. It’s paywalled — tsk, tsk — but printed here in full:
Continue reading Three retractions for Oregon neuroscience student investigated by ORI

A mess: PLOS mistakenly publishes rejected ADHD-herbicide paper, retracts it

logoPLOS One has retracted a paper that links the most commonly used herbicide to ADHD, after it was “published in error.”

According to the note, the paper was “editorially rejected following peer review and consultation with the Editorial Board,” but ended up going through the production process anyway.

When we contacted the authors, they filled us in with more details.

Continue reading A mess: PLOS mistakenly publishes rejected ADHD-herbicide paper, retracts it

First author refuses to sign PNAS retraction after “key findings” are not reproduced

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Two out of the three authors of a PNAS paper on mutations underlying lung diseases are pulling it after failing to reproduce key findings.

The paper, published in 2012, investigated how mutations in lung surfactant genes induce molecular changes that lead to lung pulmonary fibrosis and lung cancer might work. But follow-up work revealed problems. In the retraction note, last author Christine Kim Garcia and second author Christoper Cano, both at the University of Texas Southwestern Medical Center, write:

Current members of the C.K.G. laboratory are unable to reproduce key findings reported in the paper.

Here’s the retraction note in full:

Continue reading First author refuses to sign PNAS retraction after “key findings” are not reproduced

Former UCSF grad student fudged data in two papers

ORIA former graduate student at the University of California, San Francisco “knowingly falsified and/or fabricated” data in two published papers, according to the Office of Research Integrity.

According to a case summary published this morning, Peter Littlefield was working on his PhD, studying the ways that cells respond to external signals, when he published the two problematic papers. He is the first author on the papers; Natalia Jura, whose lab he worked in, is the last on both.

The report’s findings are based on, among other sources, “the respondent’s admission.”

The first paper, “Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations” was published in Science Signaling and has been cited twice, according to Thomson Scientific’s Web of Knowledge.

Three figures in the paper are problematic, says the ORI summary:

Continue reading Former UCSF grad student fudged data in two papers

Sea squirt draft paper published by mistake

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A paper on the evolution and development of urochordata — also known as sea squirts — was published in an under-developed form: Due to the publishers’ “error,” a “preliminary draft” of the article was published online in Developmental Dynamics last year.

The draft has been retracted; we can no longer find it on the site at all. The final copy of the paper has been posted in its place.

Here’s the retraction note in full for “Development, Metamorphosis, Morphology and Diversity: Evolution of Chordates muscles and the Origin of Vertebrates”:

Continue reading Sea squirt draft paper published by mistake

Following criticism, PLOS removes blog defending scrutiny of science

plos_logoCommunity blog PLOS Biologue has pulled a post by journalists Charles Seife and Paul Thacker that argued in favor of public scrutiny of scientists’ behavior (including emails), following heavy criticism, including from a group and scientist mentioned in the post.

Their reasoning: The post was “not consistent with at least the spirit and intent of our community guidelines.”

The original post, published August 13, is no longer available online, but you can read it here. In the piece, Seife and Thacker lament what they call a recent backlash against transparency in science: Continue reading Following criticism, PLOS removes blog defending scrutiny of science

Paper on narcissistic CEOs earns big correction

home_coverIt may not be much of a surprise that narcissistic CEOs of pharmaceutical companies will make bold choices, such as adopting radically new technology. That idea remains true, despite a lengthy correction to a paper that supports it.

The paper, “CEO Narcissism, Audience Engagement, and Organizational Adoption of Technological Discontinuities,” in Administrative Science Quarterly, found support for the following hypothesis:

Continue reading Paper on narcissistic CEOs earns big correction

Former Wake Forest grad student fudged data for drug study

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Brandi Blaylock

A former graduate student at Wake Forest School of Medicine “presented falsified and/or fabricated data” in a government-funded drug study, according to findings released by the U.S. Office of Research Integrity earlier today.

The report was released in the wake of an investigation conducted by the university and the ORI. Investigators found that although Brandi Blaylock recorded responses of a dozen laboratory monkeys after giving them anti-abuse drugs, she hadn’t given them the compounds “per protocol.”

Blaylock then presented the data at “two poster presentations, several laboratory meetings, and progress reports.”

Some of her research was supported by a grant from the National Institute of Drug Abuse, “Dopamine D2 Receptors In Primate Models of Cocaine Abuse,” which examined the effects of novel dopamine D3 receptor compounds on drug addiction on monkeys.

However, according to the report, Blaylock presented the falsified responses from a dozen monkeys: Continue reading Former Wake Forest grad student fudged data for drug study