Fourth retraction for Einstein oncologist due to image manipulations

home_cover (1)Two papers on a potential cancer drug have been retracted following an investigation that found “inappropriate manipulation of bands in gels.”

This makes four retractions by our count for Roman Perez-Soler, an oncologist at the Einstein College of Medicine, and for co-author Yi-He Ling, whose current affiliation is unknown.

Their previous two retractions, which we reported on in 2013, were also for image manipulation. At the time, Perez-Soler told us that Ling “accepted full responsibility for the changes” and he had “returned to his home country.”

The fresh retraction notes, from Molecular Pharmacology, provide a few specifics about the figures that were manipulated this time around.

Continue reading Fourth retraction for Einstein oncologist due to image manipulations

Kansas ecology prof loses whistleblower protection after alleging misconduct

ecologyThe U.S. government has denied whistleblower protection for a researcher who was fired from Kansas State University after alleging his colleagues misrepresented data in an ecology paper.

Researcher Joseph Craine was asked to leave K-State after being the “subject of a dismissal campaign” by colleagues when he told the Ecology journal that he believed some had been “fraudulently characterizing field studies,” according to the Topeka Capital-Journal.

In response, Craine sought whistleblower protection status from the National Science Foundation — a sponsor of the research — which was recently denied, says the Topeka Capital-Journal:

Continue reading Kansas ecology prof loses whistleblower protection after alleging misconduct

Anti-fish oil researcher netted two more retractions

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Brian Peskin

Earlier this year, Food and Nutrition Sciences retracted two papers from an author who criticized highly popular fish oil supplements after an additional round of peer review concluded his papers present a “biased interpretation,” among other issues.

Last year, Brian Peskin lost a paper for an “undeclared competing interest” — namely, that he held patents and directed a company associated with essential fatty acids.

In place of fish oil, Peskin touts plant-based supplements for treating cardiovascular disease. From the abstract of the freshly-retracted “Why Fish Oil Fails to Prevent or Improve CVD: A 21st Century Analysis,” he claims that Parent Essential Oils (PEOs) — such as alpha-linolenic acid, which can be converted into the EPA and DHA found in fish oil — “fulfill fish oil’s failed promise”: Continue reading Anti-fish oil researcher netted two more retractions

Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

American Journal of Physiology - Lung Cellular and Molecular PhysiologyAnother retraction and a correction that retracts two figures — ie, a partial retraction — have been posted for Duke University lung researchers, Erin Potts-Kant and Michael Foster.

These latest notices move the count up to 8.5 retractions for Potts-Kant and 7.5 for Foster (counting the partial retraction as 1/2), along with the correction for both. In both cases and in a familiar note from previous retractions, authors found “potential discrepancies” between two sets of data (partial retraction) and study figures that weren’t “reliable” (retraction).

The retraction comes after the authors discovered problems with three of the study figures. In the corrected paper, the authors were able to validate some of their findings after repeating the experiments, but retracted two of the study figures that they were “unable to verify.”

Continue reading Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

Researchers call for retraction of NEJM paper showing dangers of e-cigarettes

NEJMResearchers and advocates are calling for the retraction of a 2015 letter in the New England Journal of Medicine that suggested that e-cigarettes are as harmful – if not more than – traditional cigarettes.

The NEJM paper reported that e-cigarettes expose smokers to significant amounts of formaldehyde, which the authors calculated could raise lifetime cancer risk by 5-15 fold compared to the risk for regular smokers. Critics, however, have claimed that to obtain such high levels of formaldehyde, the NEJM authors superheated the vapor from the e-cigs to levels that would create a well-known, acrid puff called a “dry puff.” This sensation, they say, is so terrible that no self-respecting “vaper” would consider repeating it. In other words, allege the e-cigarette supporters, the conditions described in the Letter—which was widely reported—were not relevant to human health.

This week, Addiction published a letter from critics of the NEJM paper, along with extensive supplementary materials, a reply from some of the NEJM Letter authors, and a response letter from the critics.

In their first Addiction letter, “Research letter on e-cigarettes was so misleading it should be retracted,” authors Clive Bates and cardiologist Konstantinos Farsalinos write: Continue reading Researchers call for retraction of NEJM paper showing dangers of e-cigarettes

CDC: Falsified data did not affect C. diff results

downloadDespite the fact that a former employee of the Oregon Health Authority falsified 56 case reports that were included in a report by the U.S. Centers for Disease Control and Prevention (CDC), a re-analysis has found that the results of the report remain valid.

The report included information about 10,342 cases of potentially deadly infections due to Clostridium difficile, so removing the cases affected by the misconduct — 57 in total — “did not” alter the results, according to an analysis published today by the CDC:

Continue reading CDC: Falsified data did not affect C. diff results

Divorce study felled by a coding error gets a second chance

home_cover (1)A journal has published a corrected version of a widely reported study linking severe illness and divorce rates after it was retracted in July due to a small coding error.

The original, headline-spawning conclusion was that the risk of divorce in a heterosexual marriage increases when the wife falls ill, but not the husband. The revised results — published again in the Journal of Health and Social Behavior, along with lengthy explanations from the authors and editors — are more nuanced: Gender only significantly correlates with divorce rate in the case of heart disease.

The authors’ note, from Iowa State’s Amelia Karraker and Kenzie Latham, at Indiana University-Purdue University Indianapolis, explains that the coding error led them to over-estimate how many marriages ended in divorce:

Continue reading Divorce study felled by a coding error gets a second chance

Years after papers were withdrawn, JBC issues notices

Journal of Biological Chemistry.coverThe Journal of Biological Chemistry has posted withdrawal notices for six papers that had already been withdrawn, some more than a decade ago, in an effort to resolve “PubMed indexing problems.”

Each paper had been pulled by the author before it appeared in print, but still appeared online on the the journal’s website and in PubMed. 

By our count, the journal has posted six notices so far, and said we should expect to see more in the future.

Kaoru Sakabe the Manager of Publication Issues at the American Society for Biochemistry and Molecular Biology, which publishes JBC, provided a statement on the new withdrawal notices: Continue reading Years after papers were withdrawn, JBC issues notices

How long does it take to retract a paper? A look at the Eric Poehlman record

oriweb_logoIn 2005, the U.S. Office of Research Integrity announced that obesity researcher Eric Poehlman had committed misconduct in 10 published papers. You might think that all of those ten articles would have been retracted a decade later.

You’d be wrong. Only six of them have. Here’s what Elizabeth Wager (a member of the board of directors of The Center For Scientific Integrity, our parent non-profit organization) found when she went looking through the record. Continue reading How long does it take to retract a paper? A look at the Eric Poehlman record

Court denies request to retract gov’t press release about convicted biotech CEO

court caseA doctor and former biotech CEO lost his appeal yesterday to force the federal government to retract a press release that he claims contained errors that damaged his reputation.

But this case isn’t so straightforward — the press release in question described the verdict in a case against former InterMune CEO W. Scott Harkonen, who was convicted in 2009 of hyping the results from the company’s lung disease drug in….you guessed it, a press release.

Here’s more from the U.S. government’s description of the 2009 case:

Continue reading Court denies request to retract gov’t press release about convicted biotech CEO