Journal corrects CrossFit injury data in paper at center of lawsuit

XLargeThumb.00124278-201509000-00000.CVA study on the trendy and grueling workout regimen known as CrossFit has a correction concerning the number of participants hurt during 10 weeks of training. The paper has been the center of multiple lawsuits  — one by CrossFit, and one by a CrossFit gym owner — for allegedly over-inflating the risks associated with the regimen.

The original paper claimed that 9 of 54 participants dropped out of the study due to “overuse or injury.” The correction note says that just two left for those reasons.

The paper, published in The Journal of Strength and Conditioning Research actually concludes that CrossFit has some benefits. According to the abstract: Continue reading Journal corrects CrossFit injury data in paper at center of lawsuit

Science Signaling corrects data fudged by former UCSF student

afbb251f8bc8f71e26b313c77669d48fA paper containing data fudged by former University of California San Francisco grad student Peter Littlefield has been corrected. We knew that this was coming — last month, the Office of Research Integrity issued a report that Littlefield had admitted to misconduct, and agreed to a retraction or correction of the two affected papers.

Published in Science Signaling, “Structural analysis of the /HER3 heterodimer reveals the molecular basis for activating HER3 mutations” examined the structural details of a protein associated with cancer. It has been cited two times, according to Thomson Scientific’s Web of Knowledge.

According to the correction note, the concentration of a protein presented in one figure was “miscalculated;” in another figure, the error bars were “calculated incorrectly.”

A statement from the UCSF affirmed that principle investigator Natalie Jura has “not been implicated in any research misconduct finding,” and explains that Continue reading Science Signaling corrects data fudged by former UCSF student

Erratum for economics paper after authors “failed to cite some very relevant recent papers”

Experimental EconomicsThe authors of a paper that examined the best way to inspire creativity in the workplace have issued an erratum after they “failed to cite some very relevant recent papers in experimental economics.”

The paper, “Incentives for creativity,” was published by Experimental Economics only a few months ago — in May — by two researchers from the University of California San Diego and the University of Amsterdam. Sanjiv Erat and Uri Gneezy found that incentives don’t actually improve creativity, and competitive incentives can actually reduce creativity.

The notice updates the paper with references to four studies published between 2012 and 2015:

Continue reading Erratum for economics paper after authors “failed to cite some very relevant recent papers”

Re-analysis of controversial Paxil study shows drug “ineffective and unsafe” for teens

downloadThe antidepressant Paxil isn’t safe or effective for teens after all, says a re-analysis of a 2001 study published today in The BMJ.

The original 2001 paper in Journal of the American Academy of Child and Adolescent Psychiatry — study 329, as it’s known — helped greenlight use of the drug (generically known as paroxetine) in young people. But it’s faced accusations of ghostwriting, undisclosed conflicts of interest, and issues with data analysis since publication.

According to a BMJ feature, also published today: Continue reading Re-analysis of controversial Paxil study shows drug “ineffective and unsafe” for teens

Animal welfare breach prompts Nature correction

cover_nature (1)A 2011 letter to Nature from Harvard researchers received its second correction today, this time after discovering the researchers conducted experiments in which mice may have “experienced more pain and suffering than originally allowed for.”

That quote comes from an accompanying editorial in the journal, a rare move for a correction to a 2011 letter. But it’s an unusual correction, for a letter that found that a component of a pepper plant appeared to selectively kill cancer cells, leaving healthy cells relatively unscathed.

Here’s the first paragraph from the detailed correction notice, published today: Continue reading Animal welfare breach prompts Nature correction

Fourth retraction for Einstein oncologist due to image manipulations

home_cover (1)Two papers on a potential cancer drug have been retracted following an investigation that found “inappropriate manipulation of bands in gels.”

This makes four retractions by our count for Roman Perez-Soler, an oncologist at the Einstein College of Medicine, and for co-author Yi-He Ling, whose current affiliation is unknown.

Their previous two retractions, which we reported on in 2013, were also for image manipulation. At the time, Perez-Soler told us that Ling “accepted full responsibility for the changes” and he had “returned to his home country.”

The fresh retraction notes, from Molecular Pharmacology, provide a few specifics about the figures that were manipulated this time around.

Continue reading Fourth retraction for Einstein oncologist due to image manipulations

Kansas ecology prof loses whistleblower protection after alleging misconduct

ecologyThe U.S. government has denied whistleblower protection for a researcher who was fired from Kansas State University after alleging his colleagues misrepresented data in an ecology paper.

Researcher Joseph Craine was asked to leave K-State after being the “subject of a dismissal campaign” by colleagues when he told the Ecology journal that he believed some had been “fraudulently characterizing field studies,” according to the Topeka Capital-Journal.

In response, Craine sought whistleblower protection status from the National Science Foundation — a sponsor of the research — which was recently denied, says the Topeka Capital-Journal:

Continue reading Kansas ecology prof loses whistleblower protection after alleging misconduct

Anti-fish oil researcher netted two more retractions

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Brian Peskin

Earlier this year, Food and Nutrition Sciences retracted two papers from an author who criticized highly popular fish oil supplements after an additional round of peer review concluded his papers present a “biased interpretation,” among other issues.

Last year, Brian Peskin lost a paper for an “undeclared competing interest” — namely, that he held patents and directed a company associated with essential fatty acids.

In place of fish oil, Peskin touts plant-based supplements for treating cardiovascular disease. From the abstract of the freshly-retracted “Why Fish Oil Fails to Prevent or Improve CVD: A 21st Century Analysis,” he claims that Parent Essential Oils (PEOs) — such as alpha-linolenic acid, which can be converted into the EPA and DHA found in fish oil — “fulfill fish oil’s failed promise”: Continue reading Anti-fish oil researcher netted two more retractions

Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

American Journal of Physiology - Lung Cellular and Molecular PhysiologyAnother retraction and a correction that retracts two figures — ie, a partial retraction — have been posted for Duke University lung researchers, Erin Potts-Kant and Michael Foster.

These latest notices move the count up to 8.5 retractions for Potts-Kant and 7.5 for Foster (counting the partial retraction as 1/2), along with the correction for both. In both cases and in a familiar note from previous retractions, authors found “potential discrepancies” between two sets of data (partial retraction) and study figures that weren’t “reliable” (retraction).

The retraction comes after the authors discovered problems with three of the study figures. In the corrected paper, the authors were able to validate some of their findings after repeating the experiments, but retracted two of the study figures that they were “unable to verify.”

Continue reading Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

Researchers call for retraction of NEJM paper showing dangers of e-cigarettes

NEJMResearchers and advocates are calling for the retraction of a 2015 letter in the New England Journal of Medicine that suggested that e-cigarettes are as harmful – if not more than – traditional cigarettes.

The NEJM paper reported that e-cigarettes expose smokers to significant amounts of formaldehyde, which the authors calculated could raise lifetime cancer risk by 5-15 fold compared to the risk for regular smokers. Critics, however, have claimed that to obtain such high levels of formaldehyde, the NEJM authors superheated the vapor from the e-cigs to levels that would create a well-known, acrid puff called a “dry puff.” This sensation, they say, is so terrible that no self-respecting “vaper” would consider repeating it. In other words, allege the e-cigarette supporters, the conditions described in the Letter—which was widely reported—were not relevant to human health.

This week, Addiction published a letter from critics of the NEJM paper, along with extensive supplementary materials, a reply from some of the NEJM Letter authors, and a response letter from the critics.

In their first Addiction letter, “Research letter on e-cigarettes was so misleading it should be retracted,” authors Clive Bates and cardiologist Konstantinos Farsalinos write: Continue reading Researchers call for retraction of NEJM paper showing dangers of e-cigarettes