Journal “mistake” forces removal of toxicology study by leading scientist

We’ve seen this movie before: Researchers present a study at a scientific meeting, then learn to their surprise (and, sometimes, chagrin) that a journal has published the data in a supplement or other edition.

That’s the case with a group of UK scientists whose abstract for a meeting of the British Toxicology Society wound up in the journal Toxicology — only to be expunged when they complained.

The work was titled “Molecular mechanisms involved in resistance of CLL cells towards ABT-737, a specific BCL-2 inhibitor.Gerald Cohen, of the University of Leicester, who led the study, told us: Continue reading Journal “mistake” forces removal of toxicology study by leading scientist

Retraction for prostate cancer paper duplication leaves authors penitent, “happy”

Perhaps fittingly in today’s age of sensitive feelings, the typical reaction to a retraction (per the notices, at least) is apology. But bliss?

Expert Opinion on Investigational Drugs has a new one in the annals of penitence. At issue is a 2010 paper titled “Horizon scanning for novel therapeutics for the treatment of prostate cancer,” by Dieletta Bianchini. Turns out the authors had published the same (or nearly so) paper two months earlier in a different journal. Here’s the notice: Continue reading Retraction for prostate cancer paper duplication leaves authors penitent, “happy”

ORI findings lead to two retractions — nearly 17 years later

Well, it only took 17 years.

As two retraction notices in the September 15 issue of the Journal of Immunology note:

On October 19, 1995, the Office of Research Integrity at the National Institutes of Health found that Weishu Y. Weiser, Ph.D., formerly of the Harvard Medical School at Brigham and Women’s Hospital, committed scientific misconduct by falsifying data in biomedical research supported by two Public Health Service grants. As a result, she agreed to submit a letter to The Journal of Immunology to retract this article. The offices of The Journal of Immunology have no record of receiving such a letter and hence the article is now being retracted.

The retractions, for “Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” and “Human Recombinant Migration Inhibitory Factor Activates Human Macrophages to Kill Leishmania donovani,” both say the same thing.

“Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” has been  cited 66 times, according to Thomson Scientific’s Web of Knowledge — 40 of those times since the ORI’s report was released. The numbers for the Leishmania paper are almost identical: Continue reading ORI findings lead to two retractions — nearly 17 years later

Fifth Alirio Melendez retraction offers clues about University of Glasgow misconduct findings

A new retraction — his fifth — in the Journal of Immunology for Alirio Melendez, formerly of the National University of Singapore, the University of Glasgow, and the University of Liverpool, sheds some light on the results of an investigation by one of the universities.

Last month, a Glasgow spokesperson told Nature that the university’s investigation had been completed in October 2011, but that it did not comment on individual cases. A spokesperson, according to the Times Higher Education:

…would say only that there was “no evidence that our current staff contributed, falsified or duplicated data to any publications co-authored with (Professor) Melendez”. He also confirmed that relevant journals would be contacted where retractions or corrections were deemed necessary.

The notice for one such necessary retraction, in the September 15 issue of the Journal of Immunology, gives a few details: Continue reading Fifth Alirio Melendez retraction offers clues about University of Glasgow misconduct findings

Glasgow’s Beatson Institute investigating circumstances of Cell retraction for inappropriate images

The Beatson Institute for Cancer Research in Glasgow, Scotland is looking into how inappropriate images ended up in a Cell paper that has just been retracted.

Here’s the notice for the paper by Lynne Marshall, Niall S. Kenneth, and Robert J. White: Continue reading Glasgow’s Beatson Institute investigating circumstances of Cell retraction for inappropriate images

University College London mitochondrial biologist resigns after three retractions for image fraud

Courtesy Nature Publishing Group

A biologist at University College London (UCL) has resigned his post and taken responsibility for “inappropriate figures manipulations” in three now-retracted papers.

Assegid Garedew, formerly a senior research investigator in Salvador Moncada‘s group, stepped down earlier this summer in the midst of an investigation that should be completed soon, Moncada tells Retraction Watch.

The three retraction notices for papers by Garedew and colleagues are all similar.

From Cell Metabolism: “Mitochondrial Dynamics, Biogenesis, and Function Are Coordinated with the Cell Cycle by APC/CCDH1“, cited once, according to Thomson Scientific’s Web of Knowledge: Continue reading University College London mitochondrial biologist resigns after three retractions for image fraud

Retraction number four appears in PNAS for work of Alirio Melendez, who has resigned post at U Liverpool

Alirio Melendez, who has had three of his papers retracted amidst suspicions about 70, has had another one retracted, this one in the Proceedings of the National Academy of Sciences (PNAS). And he has also resigned from his post at the University of Liverpool, we have just learned.

Here’s the notice: Continue reading Retraction number four appears in PNAS for work of Alirio Melendez, who has resigned post at U Liverpool

Pharmacology journal expresses concern over “similar, but updated” review

The British Journal of Clinical Pharmacology has issued an “expression of concern” for a 2003 review article, based on a previous lecture, with close echoes to a paper that had appeared in one of The Lancet titles.

Here’s the notice for the article, by Peter Winstanley, dean of the Warwick Medical School in the United Kingdom: Continue reading Pharmacology journal expresses concern over “similar, but updated” review

Cardiff University looking into allegations of misconduct by group headed by its dean of medicine

Last December, we reported on a Journal of Immunology paper that was retracted after a Cardiff University investigation found the senior author had inappropriately manipulated images.  The inquiry found that there had been “no intention to mislead and subsequent repeats of the original experiments have shown that the paper’s conclusions remain sound,” the university told us at that time.

The senior author of the paper, Rossen Donev, had since moved on to the University of Swansea, and Cardiff had notified the Medical Research Council, which funded the work. The case seemed to end there.

But other work by Donev’s former lab group, which is led by BP Morgan, the dean of Cardiff’s medical school, has been the subject of scrutiny by at least one anonymous whistleblower. That whistleblower’s allegations — which also center on image manipulation — have been reported on the relatively new site Science Fraud, which posts allegations anonymously. They involve papers published in Cancer Research, Molecular Immunology, and the American Journal of Physiology.

We’ve now learned that Cardiff has “initiated its Procedure for Dealing with Allegations of Academic Misconduct in Research” after Clare Francis, another anonymous whistleblower whose name will probably be familiar to Retraction Watch readers, forwarded the concerns to university officials. Now, according to an email from Carole A Evans, Cardiff’s Director of Governance and Compliance Division: Continue reading Cardiff University looking into allegations of misconduct by group headed by its dean of medicine

Cancer journal pulls deeply flawed meeting abstract on breast surgery

The European Journal of Surgical Oncology has retracted a meeting abstract that evidently was never meant to be.

The study, by researchers at Queen Elizabeth Hospital and Good Hope Hospital, both in Birmingham, England, was to be presented at this year’s annual meeting of the Association of Breast Surgery and purported to compare rates of patient satisfaction among women who underwent two kinds of breast reconstruction, TRAM — transverse rectus abdominis myocutaneous  — flap and DIEP (short for deep inferior epigastric perforators) flap.

But according to the notice: Continue reading Cancer journal pulls deeply flawed meeting abstract on breast surgery