Author: Victoria Stern

Diabetes researcher who sued to prevent retractions now has 13

A diabetes researcher who sued a publisher to protect several papers from being retracted recently received his 13th, in a prestigious gastroenterology journal.

Mario Saad, based at the University of Campinas in São Paulo, Brazil, has had a string of retractions over the past few years, including four in Diabetes after he lost a legal battle with the American Diabetes Association.

The latest retraction appears in Gastroenterology, citing possible image duplication. Saad is second-to-last author on the 2012 paper.

According to the retraction notice, the journal investigated data in several figures, and believes some were duplicated. The authors explained that the duplications resulted from inadvertently using wrong blots; still, the editors chose to retract the paper after determining they no longer had confidence in its conclusions.  

Here’s the retraction notice for “Obesity-Induced Increase in Tumor Necrosis Factor-α Leads to Development of Colon Cancer in Mice:” Continue reading Diabetes researcher who sued to prevent retractions now has 13

Authors say patient threatened legal action after being subject of scholarly paper

A patient appears to have had a change of heart about being featured in a case report.

The patient cannot be identified in the paper published in Journal of Gastrointestinal and Liver Diseases. However, according to the retraction notice, she threatened to sue if the authors did not withdraw it. After receiving the threat, the paper’s corresponding author, Mariano Sica, told us that the authors immediately asked the journal to retract the paper.

We’ve written about similar cases where patients do not provide informed consent or withdraw it, but in this case we haven’t seen the threat ourselves.

We asked Sica if we could see the legal threat, and he said he couldn’t share it, explaining: Continue reading Authors say patient threatened legal action after being subject of scholarly paper

Nature Chemistry issues its first retraction

For the first time in its eight-year history, Nature Chemistry has retracted a paper, citing “data integrity issues.”

The 2010 paper, which explored how various iron-based molecules interact with water and ethanol, was withdrawn after the authors uncovered possible duplication in two images.

According to the retraction notice, the authors could not provide the raw data to confirm their findings and could not reproduce the figures because the experimental set-up had been dismantled. The authors subsequently requested the paper be retracted because the issues undermined “our full confidence in the integrity of the study.”

Here’s the retraction notice for “Charge transfer to solvent identified using dark channel fluorescence-yield L-edge spectroscopy”: Continue reading Nature Chemistry issues its first retraction

Author “shocked” after top math journal retracts paper

One of the world’s most prestigious mathematics journals has issued what appears to be its first retraction.

The Annals of Mathematics recently withdrew a 2001 paper exploring the properties of certain symmetrical spaces.

What prompted this retraction? And why did it occur 16 years after the paper was published? Continue reading Author “shocked” after top math journal retracts paper

Lancet retracts (and replaces) paper a year after authors report error that changes “all numbers”

In March 2016, researchers in Switzerland and Canada published a meta-analysis in The Lancet, exploring the optimal painkiller and dose for treating pain in knee and hip osteoarthritis. Soon after, the authors were informed of an error that would change “all numbers” in a paper that may influence clinical practice.

The authors contacted The Lancet immediately, in July 2016, to inform them of the issue. Sven Trelle, the paper’s corresponding author, also told us: Continue reading Lancet retracts (and replaces) paper a year after authors report error that changes “all numbers”

Are there foxes in Tasmania? Follow the poop

Stephen Sarre, based at the University of Canberra in Australia, has made a career out of collecting and analyzing poop.

It’s a tough job, but someone’s got to do it. Part of his work is designed to answer a multi-million dollar question: Is Tasmania home to foxes, a pest that carries rabies and other diseases and can ravage local wildlife? According to the Australian news outlet ABC, the Tasmanian and Australian governments have spent $50 million (AUD) on hunting foxes on the island since 2001 — even though many have debated whether they are even there.

In 2012, after analyzing thousands of fecal samples, Sarre published a paper in the Journal of Applied Ecology which boldly claimed that “Foxes are now widespread in Tasmania.” But many outside researchers didn’t buy it, and quickly voiced their criticisms of the paper, namely that there may be problems with false positives and the methodology used to analyze the samples. Recently, the journal issued an expression of concern for the paper, citing an ongoing investigation into the allegations.

Here’s the expression of concern (paywalled, tsk tsk):

Continue reading Are there foxes in Tasmania? Follow the poop

The retraction countdown: How quickly do journals pull papers?

After Tina Wenz was found guilty of scientific misconduct, how long did it take for journals to retract the problematic papers?  The answer: Between three and nine months.

In September 2016, the University of Cologne found that Wenz had committed scientific misconduct in six papers and requested they all be retracted. From that point on, the retraction clock was ticking.

We’ve explored how long it takes a journal to act over the years, and we’ve found that the time between identifying a problem to retracting the paper can vary — and sometimes last years.

In Wenz’s case, one of the papers—published in Cell Metabolism in 2009—had already been retracted in 2015. Three of the remaining five were retracted in December 2016—a 2008 paper in Cell Metabolism, a 2009 paper in Proceedings of the National Academy of Sciences (PNAS), and a 2009 paper in the Journal of Applied Physiology.

In January 2017, the journal IUBMB Life pulled a 2014 paper flagged in the investigation. And just over nine months after Wenz was found guilty of misconduct, the last paper—published in 2013 in Mitochondrion—has been retracted.

The most recent notice states that the University of Cologne requested the retractions, after determining that the data had been “inappropriately manipulated.”

Here’s the retraction notice in Mitochondrion:

Continue reading The retraction countdown: How quickly do journals pull papers?

Fake peer review, forged authors, fake funding: Everything’s wrong with brain cancer paper

The paper had everything: Fake peer review, forged authors, even a fake funder.

In other words, it had nothing.

A 2015 paper is the latest retraction stemming from an investigation into fake peer review by Springer, which has now netted more than a hundred papers.

According to a spokesperson at Springer: Continue reading Fake peer review, forged authors, fake funding: Everything’s wrong with brain cancer paper

Unintended consequences: How authorship guidelines destroyed a relationship

It started as a simple email exchange over authorship. But it angered one researcher so much that it ended a 20-year collaboration.

In January 2017, a chemist based in Mexico had finished writing a paper describing the structure of a molecule. Sylvain Bernès, at the Instituto de Física Luis Rivera Terrazas, asked his co-author—the head of the lab where the molecule had been synthesized 10 years ago—to review the draft and include any co-authors involved in the initial work.

The researcher added three co-authors to the paper. Bernès became concerned. He wanted to follow the International Committee of Medical Journal Editors (ICMJE) authorship recommendations as strictly as possible. As far as Bernès could tell, none of the new authors had actually contributed to the work, potentially violating the recommendation about authorship contributions. Continue reading Unintended consequences: How authorship guidelines destroyed a relationship

“Some experiments were not performed appropriately:” Florida researchers lose two papers

Two molecular biologists have withdrawn two 2015 papers published in the same journal, citing image duplication and manipulation, among other issues.

One notice — published in June — explains that, after further investigation, the Journal of Biological Chemistry (JBC) found certain experiments “were not performed appropriately.” The other notice cites “missing data” and notes that certain data “did not accurately represent experimental conditions.”

The authors of the papers—Daniel L. Kaplan, associate professor at Florida State University who heads a genomics lab, and Irina Bruck, assistant scholar scientist in Kaplan’s lab—also received a correction in JBC this month, which cites image duplication.

The three notices, all published this month in JBC, may reveal a pattern, but there’s still a lot we don’t know. One of the two papers was questioned on PubPeer. Several commenters flagged duplicated images and had questions about the antibody used.

Here’s one retraction notice, published this month: Continue reading “Some experiments were not performed appropriately:” Florida researchers lose two papers