Author: Shannon Palus

Duplicated data, “careless errors” expire lung cancer paper

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A paper about the molecular details of lung cancer is being retracted for repeating datasets and “careless errors” in a pair of figures.

According to the note, the editor of Carcinogenesis wouldn’t have known about the problems if he hadn’t been tipped off that the paper by first author, XiaoJuan Sun — a researcher at Shenzhen Second People’s Hospital in China — shared “significant similarities” with another one of Sun’s papers that was retracted years ago. After the journal investigated the paper, it discovered that the authors had reported the same data as in the retracted paper “without significant additions or amendments,” along with some errors and inconsistencies.

Here’s the detailed note for “The EDA-containing cellular fibronectin induces epithelial mesenchymal transition in lung cancer cells through integrin α9β1-mediated activation of PI3-K /Akt and Erk1/2:”

Continue reading Duplicated data, “careless errors” expire lung cancer paper

Journal retracts — and republishes — small study on gamma rays for OCD

Screen Shot 2015-10-28 at 8.40.00 PMJAMA Psychiatry has retracted and republished a paper on a cutting-edge procedure for patients with obsessive compulsive disorder.

In the original paper, the authors claimed that three out of eight patients who underwent a procedure that used gamma rays to kill brain cells showed improvements 12 months later (versus zero in the group who underwent a “sham” procedure). But after a reader noticed an “inadvertent” error in the calculation of how many patients had improved, the authors realized that only two of the patients had responded meaningfully to the procedure.

The new results “did not reach statistical significance,” the authors write in a “Notice of Retraction and Replacement.”  JAMA Psychiatry published it yesterday, along with a new version of the article, a letter from psychiatrist Christopher Baethge pointing out the error, and an editorial. The original article is available in the supplemental material of the new version, with the errors highlighted.

Here’s the note in full for “Gamma ventral capsulotomy for obsessive-compulsive disorder: a randomized clinical trial,” which explains the error:

Continue reading Journal retracts — and republishes — small study on gamma rays for OCD

After court verdict, BMJ retracts 26-year-old paper

downloadToday, The BMJ retracted a 1989 paper about the role of breastfeeding and formula in infant eczema — 20 years after the data were called into question by a university report.

However, the report was kept secret — due, by some accounts, to alleged threats of a lawsuit. That is, until this year, when author Ranjit Kumar Chandra — who once dubbed himself the “father of nutritional immunology” — lost a $132 million libel case. That case, against the Canadian Broadcasting Company (CBC) for airing a three-part documentary series on allegations of fraud against Chandra, pushed the report by his former employer Memorial University of Newfoundland into the public domain.

At 26 years, the BMJ retraction is a runner up for the longest amount of time a journal has taken to retract a paper. (We know of another retraction that was 27 years in the making, and a scientist who requested the retraction of some passages of a 1955 article in 2007, after the article became fodder for creationists.)

Here’s the first part of the retraction note:

Continue reading After court verdict, BMJ retracts 26-year-old paper

BMJ corrects controversial critique of US dietary guidelines report

downloadThe BMJ has published a correction to a critique of the U.S. dietary guidelines report that has received heavy criticism from nutrition experts.

The author, journalist Nina Teicholz, has also posted a response to the criticism of the article.

The BMJ investigation, released in September, asserted that the guidelines committee used “weak scientific standards” to make its recommendations. It also criticized several aspects of the new expert report for the guidelines, such as “deleting meat from the list of foods recommended as part of its healthy diets.”

Soon after the feature appeared, The Verge — who first reported the news of the correction this week — called it “bogus.” The BMJ quickly issued a “clarification” to the paper, in the “rapid response” section of the paper (the journal’s version of a comment section). It noted that the feature should have specified “lean” meats.

The new, official, correction doesn’t formally put the clarification on the record. Instead, it addresses the research behind the analysis about saturated fats. Here it is in full:

Continue reading BMJ corrects controversial critique of US dietary guidelines report

Taste researcher falsified data in two papers: ORI

ori-logoA federal report has found that a former University of Maryland postdoc “falsified and/or fabricated” data in two papers about taste receptors.

The Office of Research Integrity report found that Maria C.P. Geraedts manipulated bar graphs in the papers to “produce the desired result.” Both have been retracted. Geraedts left academia in 2014, and is now a science writer.

We reported on one retraction in July, “Gustatory stimuli representing different perceptual qualities elicit distinct patterns of neuropeptide secretion from taste buds,” published in The Journal of Neuroscience.

The other, “Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery,” published in 2012 in the American Journal of Physiology Endocrinology and Metabolism, was retracted in September. Here’s the note, which cites the university’s investigation: Continue reading Taste researcher falsified data in two papers: ORI

Bone researcher manipulated data in JAMA study, says investigation

Screen Shot 2015-10-27 at 10.53.53 AMA bone researcher manipulated data in a 2011 JAMA study about an inexpensive treatment for osteoporosis. That’s the conclusion of an investigation at the researcher’s former workplace, the Women’s College Hospital in Toronto, the Toronto Star reports.

The study — led and manipulated by Sophie Jamal — followed 243 women over two years, as they applied nitroglycerin ointment once a day. The ointment is currently used to prevent chest pain and treat anal fissure pain by relaxing blood vessels; Jamal’s study concluded it could help patients with osteoporosis, too:

Among postmenopausal women, nitroglycerin ointment modestly increased [bone mineral density] and decreased bone resorption.

But even the modest effect was too good to be true. Continue reading Bone researcher manipulated data in JAMA study, says investigation

P53 researcher submitted paper “without permission from his co-authors”

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One issue that we see pretty regularly is a paper submitted by one author without the permission of the others.

That’s what’s happened with “p53-induced Rap2B positively regulates migration in cells exposed to glucose deprivation,” published in July by Molecular Carcinogenesis. The paper looks at a protein called p53, well-known to regulate cell growth and, when mutated, cause cancer.

Here’s the pretty straightforward retraction note:

Continue reading P53 researcher submitted paper “without permission from his co-authors”

Entrepreneur ranking retracted for not being “inclusive enough”

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This is a first for us — a publication that covers start-ups in South Africa has retracted a list of 13 rising tech entrepreneurs for not being “inclusive enough.”

Lists are a staple of popular media, so much so that they’ve earned their own word: listicle. But we’ve never seen one get retracted before. We weren’t sure what metric of inclusion the retraction was referring to, but looking at an archive of the webpage, where the listicle appeared before the publication was taken down, we saw that every person on the list appears to be a man, and almost all of them white.

We asked Stuart Thomas, Senior Reporter at Memeburn — which published the list with a related publication, Ventureburn — if this was what the publication meant by not “inclusive enough:”

It was a factor, yes.

Here’s the note for “Digital All Stars 2015: 13 South African tech entrepreneurs on the rise:”  Continue reading Entrepreneur ranking retracted for not being “inclusive enough”

Serial plagiarist’s retractions upped to 14

We’ve done some digging, run the numbers, and present to you a new member of our leaderbcov200hoard: orthopedic researcher Bernardino Saccomanni. Nine newly unearthed retractions of his make for a total of 14.

We first reported on Saccomanni’s work back in 2011, and identified him as a “serial plagiarist.” In the years since, he’s continued to rack up retractions for papers on the likes of ligament reconstruction and shoulder pain. On every paper, he is listed as the sole author.

Bernardino Saccomanni’s most recently listed affiliation on the papers is “Ambulatorio di Ortopedia, via della Conciliazione.” He sometimes also lists his affiliation as Gabriele D’ Annunzio University Chieti, even though, as we learned a few years ago, he hasn’t worked there for many years.

There’s a lot to cover here, so stick with us:

1) First up, “A new test for acromio-clavicolar pathology” was published in the Journal of Clinical Orthopedics and Trauma and cited zero times according to Thomson Scientific’s Web of Knowledge. Here’s the retraction note:

Continue reading Serial plagiarist’s retractions upped to 14

Prostate cancer paper flagged by ORI is retracted following PETA prompt

cover_issue_129_en_USA federal investigation into a paper on prostate cancer has now led to a retraction. In an unusual twist, it happened following a request from the animal rights group People for the Ethical Treatment of Animals (PETA).

In January, the Office of Research Integrity reported that corresponding author Dong Xiao “intentionally fabricated data” in an Oncotarget study of how a steroid inhibits the growth of prostate cancer. Xiao, a former cancer researcher at the University of Pittsburgh, claimed that he had tumor data from more mice than he did, and falsified several figures.

In July, after no sign of the retraction, a researcher at PETA followed up with the journal, Oncotarget, on behalf of the organization “and our more than 3 million members and supporters to request the immediate retraction.”

Last month, they received a reply from the publisher, which they forwarded to us:

Continue reading Prostate cancer paper flagged by ORI is retracted following PETA prompt