Author: Alison McCook

Should peer review be open, and rely less on author-picked reviewers? Study says…

BMJ openAfter reviewing hundreds of peer review reports from three journals, authors representing publishers BioMed Central and Springer suggest there may be some benefits to using “open” peer review — where both authors and reviewers reveal their identity — and not relying on reviewers hand-picked by the authors themselves.

But the conclusions are nuanced — they found that reviewers recommended by authors do just as good a job as other reviewers, but are more likely to tell the journal to publish the paper. In a journal that always uses open reviews — BMC Infectious Diseases — reviews are “of higher quality” than at a journal where authors are blinded to reviewers, but when one journal made a switch from a blinded to an open system, the quality didn’t improve.

Here’s what the authors conclude in the abstract of the paper, published today in BMJ Open: Continue reading Should peer review be open, and rely less on author-picked reviewers? Study says…

German dep’t head reprimanded for not catching mistakes of co-author Lichtenthaler

Holger Ernst
Holger Ernst

The head of a department at WHU — Otto Beisheim School of Management has been charged with “severe scientific misconduct” for not spotting many of the data irregularities of his co-author Ulrich Lichtenthaler, which have ultimately led to 16 retractions.

According to a news release describing a WHU investigation (which we had translated using One Hour Translation), Holger Ernst did not neglect his supervisory duties, but, as a co-author on many of the retracted papers, he should have been more aware of the data issues in Lichtenthaler’s work: Continue reading German dep’t head reprimanded for not catching mistakes of co-author Lichtenthaler

Can you spot the signs of retraction? Just count the errors, says a new study

downloadClinical studies that eventually get retracted are originally published with significantly more errors than non-retracted trials from the same journal, according to a new study in BMJ.

The authors actually called the errors “discrepancies” — for example, mathematical mistakes such as incorrect percentages of patients in a subgroup, contradictory results, or statistical errors.

The study doesn’t predict which papers will eventually be retracted, since such discrepancies occur frequently (including one in the paper itself), but the authors suggest a preponderance could serve as an “early and accessible signal of unreliability.”

According to the authors, all based at Imperial College London, you see a lot more of these in papers that are eventually retracted: Continue reading Can you spot the signs of retraction? Just count the errors, says a new study

Here’s how to keep clinical trial participants honest (and why that’s a big deal)

NEJMAdditional lab tests, creating a clinical trial patient registry, and rewards for honesty are among the advice doled out in this week’s issue of the New England Journal of Medicine for researchers to help avoid the major issue of participants lying to get into clinical trials.

In the Perspective, David B. Resnik and David J. McCann, both based at the National Institutes of Health, address concerns raised by a 2013 survey of clinical trial participants that revealed “high rates” of “deceptive behavior.” Specifically: Continue reading Here’s how to keep clinical trial participants honest (and why that’s a big deal)

ASU prof placed on administrative leave following plagiarism charges

Matthew Whitaker

A faculty member at Arizona State University has been placed on leave while the university investigates charges against him.

According to a spokesperson for ASU, Matthew Whitaker

has been placed on administrative leave and relieved of all duties. The University will follow Arizona Board of Regents policy as it reviews allegations that his conduct has fallen short of the University’s expectations for a faculty member and a scholar.

In July, we reported that Whitaker was revising a book about modern African-American history after he admitted it contained Continue reading ASU prof placed on administrative leave following plagiarism charges

Animal welfare breach prompts Nature correction

cover_nature (1)A 2011 letter to Nature from Harvard researchers received its second correction today, this time after discovering the researchers conducted experiments in which mice may have “experienced more pain and suffering than originally allowed for.”

That quote comes from an accompanying editorial in the journal, a rare move for a correction to a 2011 letter. But it’s an unusual correction, for a letter that found that a component of a pepper plant appeared to selectively kill cancer cells, leaving healthy cells relatively unscathed.

Here’s the first paragraph from the detailed correction notice, published today: Continue reading Animal welfare breach prompts Nature correction

Kansas ecology prof loses whistleblower protection after alleging misconduct

ecologyThe U.S. government has denied whistleblower protection for a researcher who was fired from Kansas State University after alleging his colleagues misrepresented data in an ecology paper.

Researcher Joseph Craine was asked to leave K-State after being the “subject of a dismissal campaign” by colleagues when he told the Ecology journal that he believed some had been “fraudulently characterizing field studies,” according to the Topeka Capital-Journal.

In response, Craine sought whistleblower protection status from the National Science Foundation — a sponsor of the research — which was recently denied, says the Topeka Capital-Journal:

Continue reading Kansas ecology prof loses whistleblower protection after alleging misconduct

CDC: Falsified data did not affect C. diff results

downloadDespite the fact that a former employee of the Oregon Health Authority falsified 56 case reports that were included in a report by the U.S. Centers for Disease Control and Prevention (CDC), a re-analysis has found that the results of the report remain valid.

The report included information about 10,342 cases of potentially deadly infections due to Clostridium difficile, so removing the cases affected by the misconduct — 57 in total — “did not” alter the results, according to an analysis published today by the CDC:

Continue reading CDC: Falsified data did not affect C. diff results

How long does it take to retract a paper? A look at the Eric Poehlman record

oriweb_logoIn 2005, the U.S. Office of Research Integrity announced that obesity researcher Eric Poehlman had committed misconduct in 10 published papers. You might think that all of those ten articles would have been retracted a decade later.

You’d be wrong. Only six of them have. Here’s what Elizabeth Wager (a member of the board of directors of The Center For Scientific Integrity, our parent non-profit organization) found when she went looking through the record. Continue reading How long does it take to retract a paper? A look at the Eric Poehlman record

Court denies request to retract gov’t press release about convicted biotech CEO

court caseA doctor and former biotech CEO lost his appeal yesterday to force the federal government to retract a press release that he claims contained errors that damaged his reputation.

But this case isn’t so straightforward — the press release in question described the verdict in a case against former InterMune CEO W. Scott Harkonen, who was convicted in 2009 of hyping the results from the company’s lung disease drug in….you guessed it, a press release.

Here’s more from the U.S. government’s description of the 2009 case:

Continue reading Court denies request to retract gov’t press release about convicted biotech CEO