Archive for the ‘obstetrics and gynecology’ Category
Two more retractions have popped up for Nasser Chegini, the former University of Florida professor currently under investigation by the Office of Research Integrity (ORI).
Both retractions appear in the Journal of Clinical Endocrinology & Metabolism. The notices indicate that an investigation report from the University of Florida “found substantial data misrepresentation” in two JCEM articles about Smads, signaling molecules that carry messages from TGF-beta receptors to the nucleus.
Here’s the notice for “The Expression of Smads in Human Endometrium and Regulation and Induction in Endometrial Epithelial and Stromal Cells by Transforming Growth Factor-Beta” ( ):
Researchers at the University of Pittsburgh have retracted a paper on using thalidomide, which led to an estimated 10,000 birth defects by the time the drug was pulled from the market in 1961, to prevent chemo-induced sterility.
Alkylating agents, which prevent DNA replication in cells, are a commonly-used cancer treatment. Unfortunately they also damage the ovaries and testes, sometimes causing infertility. The University of Pittsburgh scientists published a paper in Elsevier journal Fertility and Sterility in 2011 that suggested thalidomide, which causes severe birth defects when used during pregnancy, might help protect ovaries during chemo.
However, according to the notice, the authors tried and failed to replicate their results. They had two separate scientists who were not authors take a look at the results; everyone agreed that the original study incorrectly reported the number of primordial follicles, the precursor to mature eggs.
Two Oxford journals have now put out three more retractions for ob-gyn and former University of Florida professor Nasser Chegini, who has been under ORI investigation since at least 2012. That makes a total of five retractions, by our count.
Here is the notice for “The expression profile of micro-RNA in endometrium and endometriosis and the influence of ovarian steroids on their expression” in Molecular Human Reproduction: Read the rest of this entry »
A cancer paper was retracted on September 17 for a double publication. According to the notice in which the authors admit to duplicating the “opening to the readers,” which we assume is the introduction, there was no need to cite the article “because it had not yet been printed at that time.”
Nasser Chegini, an ob-gyn formerly on the faculty at the University of Florida who has been the subject of an Office of Research Integrity (ORI) inquiry for several years, has a second retraction.
Chegini is suspected of having used bogus data in some of his work — research backed in part by some $4 million in federal funding.
This one seems like an honest mistake: a paper on dietary supplements during pregnancy has been retracted based on an error in data recording.
In the BMC Pregnancy & Childbirth paper, “Folic acid supplementation, dietary folate intake during pregnancy and risk for spontaneous preterm delivery: a prospective observational cohort study,” women for whom the researchers had no data on folic acid supplementation were classified as taking no supplements. Despite the error, the authors claim the overall conclusion remains the same: taking folic acid supplements didn’t protect women from preterm deliveries.
Imagine you were a cop, sitting in your squad car at the side of the road with a radar gun, when you clock someone speeding. You turn on your lights, pull the speedster over to the side of the road, and walk to her driver’s side window.
Just as you say “Driver’s license and registration, please,” you realize the driver is your squad captain. Oops.
That must have been something like what it was like — with plagiarism detection software sitting in for the radar gun — for the co-editor-in-chief of Diabetology & Metabolic Syndrome when he realized that Marilia de Brito Gomes, the other co-editor-in-chief, had published two papers in their journal that contained plagiarized passages.
Blood has retracted two 2013 illustrations of red cells by researchers from South Africa and the United States because, somewhat confusingly, they didn’t conform to the journal’s criteria for publishing such material.
Willibrord Weijmar Schultz, the Groningen sex researcher (and Ig Nobel winner) who misused the 1985 thesis of an American scholar, and the work of another researcher, in at least five published articles, has tallied another retraction in the affair, his sixth.
As we reported earlier, Schultz had been cleared of plagiarism but found to have abused the work (in an “unintended and unknowing” fashion, we’re told) of one Diana Jeffrey, by taking passages from her dissertation without acknowledgement. These articles are pretty long in the tooth, having been published in the 1990s.
The latest, in the Journal of Sex Education and Therapy, appeared in 1992. Titled “Sexual rehabilitation after gynecological cancer treatment,” Schultz wrote it with a colleague H.B.M. Van de Wiel, whose name shows up on the other retractions, too.
The case involved allegations by the plaintiffs — two children who had suffered permanent birth defects and their mothers — that they had lost previous malpractice suits because a fraudulent case report was being used to bolster the defense.
The case targeted two ob-gyns, Henry Lerner, of Harvard, and Eva Salamon, of the Bond Clinic, in Winter Haven, Fla., who had published the case study in question. It also named the clinic itself and the American Journal of Obstetrics & Gynecology, which published the article in early 2008.
The article, titled “Permanent brachial plexus injury following vaginal delivery without physician traction or shoulder dystocia,” purported to show: