Archive for the ‘cell press’ Category
We have an update on the case of Pankaj Dhonukshe, a scientist about whom we reported in November. Utrecht University has found that Dhonukshe, a former researcher at the Dutch university, committed “a violation of academic integrity” in work that led to a number of papers, including one published in Nature and once since retracted from Cell.
Cell update: Co-corresponding author let go from Belgian university; retraction notice language changed
We’ve learned more about the circumstances behind a Cell retraction that we covered last week.
First, one of the two corresponding authors left the institution where he most recently worked. Belgium’s VIB Ghent told us that Pankaj Dhonukshe was no longer employed there and said: Read the rest of this entry »
The article, “Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK,” came from the lab of Jef Boeke, a celebrated biochemist. But a former lab member, Daniel Yuan, who was fired by Hopkins in late 2011 after 10 years at the institution, had repeatedly raised questions about the validity of the findings. Those concerns eventually made their way into the Washington Post, prompting this response from the university. Read the rest of this entry »
A team of researchers led by Daniel St. Johnston, director of the Gurdon Institute at Cambridge and a prominent developmental biologist in the UK, has lost a pair of articles after finding that their data were unreliable. But rather than “correct” the record with subsequent papers, they’ve withdrawn the problematic work.
To our mind, this is a poster case of doing the right thing by science. We think the notices — as provided by the authors and reported by the journals — pretty much say it all, so we’ll let them speak for themselves, followed by some details St. Johnston shared with us.
The first article, “LKB1 and AMPK maintain epithelial cell polarity under energetic stress,” appeared in 2007 in the Journal of Cell Biology and has been cited 108 times, according to Thomson Scientific’s Web of Knowledge.
According to the retraction notice:
MIT’s Robert Weinberg, a leading cancer researcher who retracted a Cancer Cell paper earlier this year for “inappropriate presentation” of figures, has corrected a different paper in the same journal.
Here’s the correction for “Species- and Cell Type-Specific Requirements for Cellular Transformation:”
We were apprised recently of errors made in the assembly of Figures 2B, 3A, 4A, 4B, and 5G, resulting in the incorporation of incorrect representative images in these figures. These errors occurred during the electronic assembly and have no bearing on the conclusions of the study. The corrected figures are shown below. The authors apologize for any possible confusion this might have caused.
Here’s the original Figure 2 and caption, followed by the new version (read all the way to the end of the post for more details on how this came to light): Read the rest of this entry »
Cell is looking into whether the authors of a widely hailed study published last week claiming to have turned human skin cells into embryonic stem cells manipulated images inappropriately, Retraction Watch has learned.
The potential image problems came to light on PubPeer, a site designed to allow for post-publication peer review. A commenter, identified as Peer1, identified “several examples of image reuse which might be of interest to PubPeer members and readers:” Read the rest of this entry »
The work of Sam W. Lee, a cancer biologist at Harvard and Massachusetts General Hospital, has come under fire at Science Fraud lately over concerns about the possible reuse of images in his group’s published studies.
Turns out there’s some there, there after all. The journal Current Biology has issued a pretty thorny correction for one of Lee’s 2006 articles, “RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress,” citing multiple issues with its figures: Read the rest of this entry »