Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘freely available’ Category

“The article must be retracted:” Journal pulls prostate cancer study

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A 2016 paper exploring the biology of prostate cancer has been retracted due to figure manipulation.

According to the retraction notice, a reader contacted the journal Clinical Cancer Research in late 2016 with concerns that similar bands appeared multiple times in two images. The editors asked the paper’s corresponding author, Shahriar Koochekpour, about the issue and requested the raw data for the figures. But Koochekpour, based in the Departments of Cancer Genetics and Urology at Roswell Park Cancer Institute in Buffalo, New York, at the time of the study, could not locate the raw data.

Since the lab did not have raw data from such a relatively recent paper, the editors reached out to the research integrity officer at Roswell Park Cancer Institute to investigate. Indeed,  the research integrity officer contacted confirmed that two figures were problematic, and requested the paper be retracted.

Here’s the rather detailed retraction notice, published in July 2017, for “GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models:” Read the rest of this entry »

The three-year delay: Journal finally retracts paper based on made-up data

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Three years after an investigation revealed a 2013 paper was based on fraudulent data, a journal has finally retracted it.

The paper, published in Journal of Hazardous Materials, was one of seven articles by a team at the Institute of Microbial Technology (IMTECH) in Chandigarh, India that contain fabricated data, according to an investigation by the Council of Scientific and Industrial Research in New Delhi. (IMTECH is part of the Council of Scientific and Industrial Research.) Although it took one journal years to take action, another still has not retracted one of the seven flagged papers. Read the rest of this entry »

Newspaper series prompts CDC to correct paper on Legionnaire’s disease

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Post-publication peer review isn’t just for scientists. Newspaper reporters can help correct the scientific record, too.

The U.S. Centers for Disease Control and Prevention (CDC) has corrected a journal article on Legionnaire’s disease after the Pittsburgh Post-Gazette revealed what seems to be efforts by the researchers to misrepresent their data.

In a series of articles last December, the newspaper raised questions about the CDC’s actions in the aftermath of outbreaks in 2011 and 2012 of Legionnaire’s that sickened 22 veterans, killing six. The Post-Gazette obtained emails from CDC scientists that appeared to reveal their disdain for the sterilization method the hospital had been using to suppress the growth of Legionella bacteria. That method, a copper-silver system, is widely considered to be effective. But according to the newspaper, the CDC investigators were so critical of the copper-silver disinfectant technology that the VA ultimately switched to a system based on chlorine.   Read the rest of this entry »

“The data have spoken:” Controversial NgAgo gene editing study retracted

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The author of a 2016 paper describing a potentially invaluable lab tool has retracted it, following heavy criticism from outside groups that could not reproduce the findings.

The paper had already been tagged with an Expression of Concern by the journal, Nature Biotechnology, which included data from multiple groups casting doubt on the original findings. Although the authors, led by Chunyu Han at Hebei University of Science and Technology in China, produced data to support their original findings, the journal has concluded — following “feedback from expert reviewers” — that the additional data “are insufficient to counter the substantial body of evidence that contradicts their initial findings,” according to an editorial released today:

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Author admits to manipulating more than a dozen images in 2013 paper

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A former graduate student at the University of Hong Kong confessed to making “inappropriate modifications” to several figures in a 2013 paper in the Journal of Biological Chemistry (JBC).

According to the retraction notice, the authors identified issues in 13 images while reviewing the data; the paper’s first author, Yingying Lu, copped to manipulating the figures. Even though “these modifications did not change the results or interpretations of this work,” the authors requested the paper be retracted.

The paper’s corresponding author, Jainbo Yue, previously based at the University of Hong Kong and now at the City University of Hong Kong, had nothing to add to the retraction notice, and told us that a “third person” is repeating the key experiments.

Here’s the retraction notice for “Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH,” published in July: Read the rest of this entry »

Written by Victoria Stern

August 2nd, 2017 at 8:00 am

After 35 years, philosophy journal corrects article…by a cat

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A cat philosopher, via Pixabay

In 1982, Bruce Le Catt wrote a response to a paper in the Australasian Journal of Philosophy critiquing an earlier article about prosthetic vision.

But Le Catt was no ordinary author. No, he was a cat, the beloved pet of David Lewis, a world-class philosopher who just happened to be the author of the article about which Bruce Le Catt was commenting.

Lewis’ inside joke wasn’t lost on those who knew him, and the benign deception seems to have been common knowledge in the field since the Le Catt paper appeared in 1982 (which also happens to be the year Cats began its run on Broadway). The paper has been cited four times since it was published, according to Clarivate Analytics. But 25 years later, the journal has finally decided to put an end to the gag.

The joyless notice states plainly: Read the rest of this entry »

Written by amarcus41

August 1st, 2017 at 2:42 pm

Researcher who stole manuscript during peer review earns second retraction

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The researcher whose brazen theft of a manuscript he had reviewed prompted a “Dear plagiarist” letter from the aggrieved author once the deceit was discovered has lost a second paper for plagiarism.

International Scholarly Research Notices, a Hindawi publication, has retracted a 2012 study by Carmine Finelli and colleagues, citing widespread misuse of text from two previously published articles. The removal was prompted by the curiosity of a scientist in England who, on reading about Finelli’s first retraction, made the logical assumption: once a plagiarist, often a plagiarist.

The review article was titled “Physical Activity: An Important Adaptative Mechanism for Body-Weight Control.” The journal is not indexed by Clarivate Analytics’ Web of Science, but the paper has been cited seven times, according to Google Scholar. According to the retraction notice: Read the rest of this entry »

Written by amarcus41

August 1st, 2017 at 8:00 am

Journal retracts paper it says authors published twice. Authors disagree.

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A journal has retracted a 2012 paper after determining that the authors had already published it elsewhere.

According to the retraction notice, the editors-in-chief of the Journal of Occupational Medicine and Toxicology concluded that the article had  been published in another journal—In Vitro Cellular & Developmental Biology – Animal—the previous month. The authors, however, did not agree to the retraction.

The research, led by Ali Khavanin, who is based at Tarbiat Modares University in Tehran, Iran and is corresponding author on both papers, evaluated whether the vibrations from industrial machinery can harm hearing in rabbits (1, 2).

Here’s the retraction notice for “Assessment of the influence of whole body vibration on Cochlear function”: Read the rest of this entry »

Why did it take a journal two years to retract a paper after a misconduct finding?

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A 2014 paper containing data manipulated by a former graduate student has finally been retracted, two years after the U.S. Office of Research Integrity (ORI) published its findings.

In August 2015, the ORI published a report that Peter Littlefield, who was working on his PhD at the University of California, San Francisco (UCSF), had committed “research misconduct by falsifying and/or fabricating data” in two papers. Littlefield agreed to correct or retract the papers–one published in Chemistry & Biology and the other in Science Signaling.  

When we contacted Chemistry & Biology back in August 2015, a spokesperson for Cell Press told us the journal was figuring out “the best way to correct the scientific record.”

Apparently that took two years. In the meantime, the journal did not issue an expression of concern or otherwise notify readers of the issues. Read the rest of this entry »

Controversial CRISPR paper earns second editorial note

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Against the authors’ objections, Nature Methods has added an expression of concern to a 2017 paper that drew fire for suggesting a common gene editing technique could cause widespread collateral damage to the genome. The latest note — the second to be added in two months — alerts readers to an alternative interpretation of the findings.

When “Unexpected mutations after CRISPR–Cas9 editing in vivo” was published May 30, it immediately drew criticism from many of the top scientists working with CRISPR, including those associated with companies seeking to develop CRISPR-based therapies for humans. Share prices for the two largest companies pursuing CRISPR therapies, Editas Medicine and Intellia Therapeutics, dropped following publication of the article.

On June 14, the journal published a notice to alert readers to “technical criticisms” of the paper. Apparently, that wasn’t sufficient, because the journal is now providing more details on the nature of the criticisms, despite the objections of the paper’s authors:

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