MD Anderson postdoc faked results of Novartis anti-cancer compound study

jun fu
Raymond Sawaya, director of MD Anderson’s brain tumor program, presents Jun Fu with the 2014 Caroline Ross Endowment Fellowship.

A former postdoc at MD Anderson Cancer Center faked the results of a mouse study of a Novartis compound designed to fight brain tumors, according to the Office of Research Integrity (ORI).

Jun Fu “admitted to knowingly and intentionally falsifying Figure 8a” in “Novel HSP90 Inhibitor NVP-HSP990 Targets Cell-Cycle Regulators to Ablate Olig2-Positive Glioma Tumor–Initiating Cells,” a paper published in Cancer Research on May 15, 2013:

Continue reading MD Anderson postdoc faked results of Novartis anti-cancer compound study

Article about alcohol withdrawal withdrawn

A stumble in data preparation earned a retraction for a paper on delirium tremensalcohol_and_alcoholism, a life-threatening side effect of alcohol withdrawal that spans a wide range of symptoms, including hallucinations and seizures.

Though the initial retraction notice was extremely unhelpful, the author stepped in to give us a better picture of the errors that led to the paper’s demise.

Here’s the notice from Alcohol and Alcoholism about “Biochemical Predictors of Delirium Tremens in Patients in Alcohol Withdrawal”:

Continue reading Article about alcohol withdrawal withdrawn

UT-Southwestern cancer research group notches ninth retraction

lung cancerA research team at the University of Texas-Southwestern that has retracted eight papers for image manipulation has retracted another, this one in Lung Cancer.

Here’s the notice for “Aberrant methylation of Reprimo in lung cancer,” published by Adi Gazdar’s group: Continue reading UT-Southwestern cancer research group notches ninth retraction

Authors retract paper “confirming” that narcolepsy is an autoimmune disease

stmA group of researchers at Stanford and elsewhere is retracting a 2013 paper that another scientist told Nature was “one of the biggest things to happen in the narcolepsy field for some time.”

The Science Translational Medicine paper caused a buzz because it claimed to show that narcolepsy was an autoimmune disease. Here’s the notice: Continue reading Authors retract paper “confirming” that narcolepsy is an autoimmune disease

Mega-correction appears for Florida leadership scholar Walumbwa following six retractions

Fred Walumbwa, via FIU
Fred Walumbwa, via FIU

Fred Walumbwa, the leadership researcher at Florida International University who has retracted six papers for what appear to be problematic data, now has an impressive mega-correction in the form of an “addendum.”

The paper, “Relationships between Authentic Leadership, Moral Courage, and Ethical and Pro-Social Behaviors,” was published in Business Ethics Quarterly in October 2011, by Walumbwa and two colleagues, Sean Hannah and Bruce Avolio.

Here’s the abstract for the paper, which has been cited 18 times, according to Thomson Scientific’s Web of Knowledge:

Continue reading Mega-correction appears for Florida leadership scholar Walumbwa following six retractions

Bitter rheumatology authorship dispute ends in retraction

rbrA 2012 expression of concern prompted by an authorship dispute has been upgraded to a retraction.

As we reported in 2012, Revista Brasiliera de Reumatologia (aka the Brazilian Journal of Rheumatology) issued an expression of concern about “Anticitrullinated peptide antibodies and rheumatoid factor in Sudanese patients with Leishmania donovani infection” after

a claim from one of the authors, questioning the authorship of the corresponding author, and informed that the article was under submission to another journal.

The journal sought the advice of the Committee on Publication Ethics (COPE), and continued its investigation. That investigation is apparently now complete, and this retraction notice is the result: Continue reading Bitter rheumatology authorship dispute ends in retraction

“Authors, please call us. Pretty please? OK, we’re going to retract your paper!”

dovelogoThe title of this post isn’t exactly how the one-sided conversation between the editors of Neuropsychiatric Disease and Treatment and a group of researchers went. But it seems likely it was pretty close.

Here’s an expression of concern for “A cross-sectional study on perception of stigma by Chinese schizophrenia patients:” Continue reading “Authors, please call us. Pretty please? OK, we’re going to retract your paper!”

Who moved my ants? Species confusion sinks paper on invasive species

Image via Wikimedia

“How many and which ant species are being accidentally moved around the world?,” published in 2013, has been retracted because the authors “used a wrong list of species and omitted to include a reference.”

The authors claim that this affected the magnitude of the issue, but not the overall conclusion.

The paper was written up by the press several times, including by the BBC, though according to Thomson Scientific’s Web of Knowledge, it hasn’t been cited.

Here is the notice: Continue reading Who moved my ants? Species confusion sinks paper on invasive species

“Positivity ratio” research now subject to an expression of concern

An expression of concern has been issued for the second of three papers on the idea that, if you have three positive emotions for every negative one, you will be more successful in life.

Psychologist Barbara Fredrickson, of the University of North Carolina, Chapel Hill, has spent the last decade building a brand around this ratio, initially described by a mathematical equation based on fluid dynamics by mathematician Marcial Losada. You can read our coverage of the debunking of that equation, presented in a 1999 paper that has been cited nearly 1,700 times, here.

Nick Brown, co-author with Alan Sokal on the paper that discredited the Losada equation, has written a blog post on the current state of affairs. He also got in touch with us regarding the expression of concern for a 2004 article in American Behavioral Scientist that he had also questioned, “The Role of Positivity and Connectivity in the Performance of Business Teams: A Nonlinear Dynamic Model”: Continue reading “Positivity ratio” research now subject to an expression of concern

ORI sanctions collaborator of Nobel winner Buck for data fabrication

ori logoThe Office of Research Integrity has sanctioned a former researcher in the lab of Linda Buck, winner of the 2004 Nobel Prize in Physiology or Medicine, for falsifying data in two papers written with the support of grants from the National Institutes of Health.

The researcher, Zou Zhihua, worked with Buck as a post-doc at Harvard and then at the Fred Hutchinson Cancer Research Center, in Seattle, Buck’s current home. After leaving there in 2005, he spent three years at the University of Texas Medical Branch in Galveston, and now appears to be a faculty member at Jilin University in China.

According to the report:

Continue reading ORI sanctions collaborator of Nobel winner Buck for data fabrication