In a quote that has become part of medical school orientations everywhere, David Sackett, often referred to as the “father of evidence-based medicine,” once famously said: Half of what you’ll learn in medical school will be shown to be either dead wrong or out of date within five years of your graduation; the trouble is … Continue reading So how often does medical consensus turn out to be wrong?
Flawed research that leads to retractions is a problem for editors, publishers and the scientific community. But what about patients? In a recent issue of the Journal of Medical Ethics, R. Grant Steen asks the question — and answers it in the affirmative. We’ve heard from Steen before; he has written two recent papers on … Continue reading No academic matter: Study links retractions to patient harm
The British Journal of Ophthalmology has retracted a 2006 paper which purported to show a link between drugs for erectile dysfunction and a rare form of sudden vision loss called non-arteritic anterior ischaemic optic neuropathy, more commonly known as “Viagra blindness.” That wouldn’t be terribly interesting, except for this: One of the authors of the paper, … Continue reading Retractile dysfunction? Author says journal yanked paper linking Viagra, Cialis to vision problem after legal threats
About a month ago, the New England Journal of Medicine told us that they didn’t “have any plans” to retract a paper by Anil Potti. Apparently, they’ve changed their minds. Today, they posted this retraction notice:
With the third retraction of a paper by Anil Potti this weekend, plus details of various investigations dribbling out, we decided to check in with the world’s two leading medical journals about whether they planned to retract the papers of Potti’s they’d published. JAMA published two papers by Potti and colleagues: One, “Gene Expression Signatures, … Continue reading No Potti retractions on the horizon from JAMA, NEJM
If you’re a savvy Retraction Watch reader — or if you’ve paid any attention at all to the news in the last 18 hours — you will have heard by now that the BMJ has called Andrew Wakefield’s work on autism and the MMR vaccine a “hoax.” The February 2010 retraction of the original Wakefield … Continue reading Some quick thoughts and links on Andrew Wakefield, the BMJ, autism, vaccines, and fraud
It’s fair to say that we haven’t heard the last of Anil Potti, the Duke cancer researcher who resigned last month following revelations that he had faked some of his results. Duke is still investigating the situation, and has also asked the Institute of Medicine to conduct its own study into the case and its … Continue reading More on Anil Potti: Two other papers worth keeping an eye on
In our very first post, we noted the case of Anil Potti, a Duke researcher who posed as a Rhodes Scholar and appears to have invented key statistical analyses in a study of how breast cancer responds to chemotherapy[.The case] has sent ripples of angst through the cancer community. Potti’s antics prompted editors of The … Continue reading A retraction in the Potti case?
Both Retraction Watch bloggers are all too familiar with the artwork in dermatology journals. One of us, AM, used to write for Skin & Aging, while the other, IO, waited eagerly for issues of Cutis sent to his pediatrician father to show up on the coffee table. And IO recently broke the incredibly important story … Continue reading Warts and all: Derm pub retracts plantar paper after author cries foul
Last week’s big Retraction Watch news — which got us quoted in the New York Times — was a Nature paper by Amy Wagers and Shane Mayack. The now-retracted paper suggested that the aging of stem cells could be reversed, and Blood has issued a notice of concern about a second paper. Now comes news … Continue reading Another stem cell paper retracted, for “breach of established ethical guidelines”