Category: image manipulation

JCO expresses concern over images from Spanish group that had aroused earlier concern

The Journal of Clinical Oncology has issued an expression of concern about a 2003 article by a group of researchers in Spain who appear to have had recurrent problems with images.

The paper has been cited 56 times, according to Thomson Scientific’s Web of Knowledge. Here’s the notice:

It has been brought to our attention, regarding Figure 1, Part A, that similarity exists between bands 3, 4, and 5 of the top row and bands 1, 2, and 3 of the bottom row, including the presence of artifacts, in the April 15, 2003 article by [Jose] RomanGomez et al, entitled, “Cadherin-13, a Mediator of Calcium Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa” (J Clin Oncol 21:1472-1479, 2003).  This similarity has raised concerns about whether these rows represent independent data. We alerted the corresponding author, Dr. Roman-Gomez, of this concern, and he has repeated the experiment shown in the original Figure 1, with the results below. Although the results of the figure appear to be unchanged, we wish to inform the readers of this issue, so that they may make their own independent assessment.

Continue reading JCO expresses concern over images from Spanish group that had aroused earlier concern

Can we trust Western blots?

The title of this post is the headline of our latest column for LabTimes. It’s inspired by a number of animated discussions on Retraction Watch following our coverage of various Western blot problems — some unintentional, and some, well, less so.

Take, for example, this comment, which we quote in the column: Continue reading Can we trust Western blots?

Three more retractions for resveratrol researcher Dipak Das, in free radical journals

Das, via UConn

The retraction count for Dipak Das, the resveratrol researcher whom the University of Connecticut found to have committed 145 counts of fabrication and falsification of data, has risen to eight with withdrawals by Free Radical Biology & Medicine and Free Radical Research.

The two Free Radical Biology & Medicine retractions, for “Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol” (cited 38 times, according to Thomson Scientific’s Web of Knowledge) and “Redox regulation of resveratrol-mediated switching of death signal into survival signal” (cited 32 times), are carefully detailed and read the same way: Continue reading Three more retractions for resveratrol researcher Dipak Das, in free radical journals

Cell paper, once plagiarized, pulled for dodgy figures

A while back (last June, to be precise), we wrote about a group of Japanese endocrinologists who found a creative way to up their citation counts using duplicate publication. At the time, the researchers were docked a 2004 paper in the Journal of Steroid Biochemistry & Molecular Biology that had self-plagiarized extensively from a 2003 article in Cell.

Well, skeptics of this new math take heart: The group’s publication total has fallen yet again. Turns out that 2003 paper — which has been cited 160 times, up from 144 when we checked last year, according to Thomson Scientific’s Web of Knowledge — wasn’t quite up to snuff, either.

According to the retraction notice for the article, “The Chromatin-Remodeling Complex WINAC Targets a Nuclear Receptor to Promoters and Is Impaired in Williams Syndrome:” Continue reading Cell paper, once plagiarized, pulled for dodgy figures

Two more retractions in respiratory journal as University of Louisville completes investigation

Last July, we reported on four retractions by a group of researchers at the University of Louisville, and we noted that the scientists’ work was under investigation. That investigation has apparently concluded, according to a retraction notice in the American Journal of Respiratory Cell and Molecular Biology for two of their papers: Continue reading Two more retractions in respiratory journal as University of Louisville completes investigation

ORI: Former SUNY Upstate neuroscience dept. chair Miller manipulated data in four grant applications

Last month, we reported on two retractions by the former neuroscience and physiology department chair at the State University of New York (SUNY) Upstate Medical University in Syracuse. Both of the retractions were requested by the university after an investigation found that Michael W. Miller had committed misconduct.

Now, the Office of Research Integrity (ORI), which reviews misconduct investigations by NIH grantee institutions, has weighed in. As detailed in the Federal Register, ORI found that Miller falsified or fabricated data in four NIH grant applications, the two published (and now retracted) papers, and one manuscript submitted to the Proceedings of the National Academy of Sciences (PNAS). For example, he Continue reading ORI: Former SUNY Upstate neuroscience dept. chair Miller manipulated data in four grant applications

Cell runs a lengthy correction, rather than retraction, for image problems

The journal Cell has an interesting — and somewhat puzzling — correction this month that we’ll add to our “mega-correction” file.

At issue is a paper, published in October, from the lab of Harvard’s Stephen Elledge, a noted genetics researcher, whose first author is a post-doc there named Michael Emanuele.

According to the notice, Emanuele (singled out, we note) seems to have been rather careless with the images used in the article, titled “Global Identification of Modular Cullin-RING Ligase Substrates”: Continue reading Cell runs a lengthy correction, rather than retraction, for image problems

Tsuji explains why JBC paper was retracted: Western blot problems

Last week, we reported on the retraction of a paper in the Journal of Biological Chemistry (JBC) that had one of the journal’s typically inscrutable retraction notices.:

This article has been withdrawn by the authors.

Late last week, we heard back from corresponding author Takashi Tsuji by email. It turns out one of our commenters had basically figured out what was wrong. It was, as seems to often be the case lately in retractions we cover, troubles with Western blots: Continue reading Tsuji explains why JBC paper was retracted: Western blot problems

University of Perugia researcher faces trial for embezzlement, fraud following 13 retractions and Expressions of Concern

Stefano Fiorucci, a gastroenterology researcher at the University of Perugia in Italy, has been indicted for fraud and embezzlement, after a university investigation found that he had manipulated images in papers that he used to win about 2 million Euros in grant funding.

The case, which has so far resulted in four retractions and nine Expressions of Concern, has dragged on for several years. The trial is scheduled for July. It’s the first time that embezzlement charges have been brought against a scientist found to have committed fraud, according to reports in Umbria 24 and the Umbria Journal.

Fiorucci’s attorney, Stefano Bagianti, told Umbria 24 that there was Continue reading University of Perugia researcher faces trial for embezzlement, fraud following 13 retractions and Expressions of Concern

Journal of Neurochemistry retracts paper after SUNY Upstate medical school finds evidence of fraud

Following an investigation by the State University of New York (SUNY) Upstate into the work of one of its neuroscientists, the Journal of Neurochemistry has retracted a 2007 paper.

The retraction notice is quite clear about why the paper is being withdrawn: Continue reading Journal of Neurochemistry retracts paper after SUNY Upstate medical school finds evidence of fraud