Category: image manipulation

Papers on potential cancer drugs retracted for image manipulation

ccr 9-13A group of researchers at the Einstein College of Medicine in the Bronx, New York has retracted two papers for image manipulation.

The retraction notices for “PM02734 (Elisidepsin) Induces Caspase-Independent Cell Death Associated with Features of Autophagy, Inhibition of the Akt/mTOR Signaling Pathway, and Activation of Death-Associated Protein Kinase” and “The Phosphatase Inhibitor Menadione (Vitamin K3) Protects Cells from EGFR Inhibition by Erlotinib and Cetuximab” say the same thing: Continue reading Papers on potential cancer drugs retracted for image manipulation

Author with six recent corrections retracts JBC paper questioned on PubPeer

jbc 8-23-13Rakesh Kumar, a professor at the George Washington University, has retracted a paper in the Journal of Biological Chemistry (JBC) that was recently questioned on PubPeer.

Here are Peer1’s comments from PubPeer about the paper, “Mechanism of MTA1 Protein Overexpression-linked Invasion:” Continue reading Author with six recent corrections retracts JBC paper questioned on PubPeer

Retraction appears for Harvard scientist who had two mega-corrections last year

molecular cellSam Lee, a Harvard biologist who had two mega-corrections published last year, has retracted a paper in Molecular Cell because some of the figures were “inappropriately assembled.”

Here’s the notice for “GAMT, a p53-Inducible Modulator of Apoptosis, Is Critical for the Adaptive Response to Nutrient Stress:” Continue reading Retraction appears for Harvard scientist who had two mega-corrections last year

Nano Letters retracts chopstick nanorod paper questioned this week on chemistry blogs

NANO LettersA chemistry paper on nanorods that became a lightning rod for criticism on chemistry blogs this week has been retracted.

Here’s the notice for “Chopstick Nanorods: Tuning the Angle between Pairs with High Yield,” originally published in June in Nano Letters by Rajasekhar Anumolu and Leonard F. Pease of the University of Utah: Continue reading Nano Letters retracts chopstick nanorod paper questioned this week on chemistry blogs

Authors withdraw already-corrected JBC paper questioned on PubPeer

jbc 8-9-13An assistant professor of neuroscience at Tufts has withdrawn a paper published last year after one round of corrections wasn’t enough to fix all of the study’s problems.

The study, “Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein,” by Gizem Donmez and colleagues, had already been subject to an extensive correction in May: Continue reading Authors withdraw already-corrected JBC paper questioned on PubPeer

Aussie university halts trials of skin cancer drug whose developer has four retractions

khachigian
Khachigian

An Australian university has put a hold on trials of an experimental drug for skin cancer whose main developer has been dogged by charges of research misconduct for several years.

The Australian Broadcasting Corporation is reporting that the University of New South Wales has suspended trials of the drug, DZ13, while it investigates the work of Levon Khachigian, who is leading the studies.

According to the news organization, Khachigian and his group were cleared by the school in two prior inquiries. However, additional accusations of misconduct — specifically involving image manipulation and misuse — prompted a third investigation.

We’ve found four retractions of Khachigian’s studies, from the Journal of Biological Chemistry and Biochemical and Biophysical Research Communications, between 2009 and 2010 (before the launch of Retraction Watch).

They are: Continue reading Aussie university halts trials of skin cancer drug whose developer has four retractions

University of Utah finds former faculty member guilty of misconduct because of “reckless disregard”

utahSince last May, we’ve been reporting on a case at the University of Utah involving two retractions and two corrections. When the story first broke, the lab blamed a former worker for inappropriately removing data from the premises, and the university has been investigating. Last month, we reported that Ivana De Domenico, the junior faculty member who was first author on those papers, had left the university, and that senior author Jerry Kaplan had retired.

But the problems went beyond the four papers we reported on, as the Salt Lake Tribune reported on Friday. In a 9-page report provided to the Tribune, the panel overseeing the investigation details its examination of 11 papers. This is the first of six findings: Continue reading University of Utah finds former faculty member guilty of misconduct because of “reckless disregard”

Melendez Science paper retracted, making 13

alirio_melendezAlirio Melendez, who has already had 12 papers retracted from various journals and been found guilty of scientific misconduct by a former employer, has had a Science paper retracted.

Here’s the notice (which is behind a paywall): Continue reading Melendez Science paper retracted, making 13

Tokyo panel calls for retraction of 43 Kato papers

katoThe University of Tokyo panel investigating the work of a former professor there, Shigeaki Kato, has recommended the retraction of 43 of his group’s articles, according to a report in the Asahi Shimbun newspaper.

If the papers are indeed retracted, Kato, who already has at least five articles subject to an expression of concern and five retractions, would be fifth on the list of most retractions for a single author, by our unofficial tally. His fellow countryman, Yoshitaka Fujii, continues to hold the lead at what appears to be 183, followed by Joachim Boldt (~89), John Darsee (~83), and Diederik Stapel, at 53. [See note at end.]

The Asahi report quotes Kato — who has received some $20 million in government funding for his work  — as acknowledging problems with the data in his studies: Continue reading Tokyo panel calls for retraction of 43 Kato papers

Paper by Canada Research Chair retracted from journal he edits for blots “from unrelated samples”

skeletal muscleA lab run by a Canada Research Chair at the Ottawa Research Institute has retracted a paper — in a journal the chair edits — for what sounds a lot like inappropriate image manipulation.

Here’s the notice from Skeletal Muscle: Continue reading Paper by Canada Research Chair retracted from journal he edits for blots “from unrelated samples”