Category: genetics retractions

Geneticists take HeLa sequence off-line after Lacks family notes they hadn’t given consent

g3HeLa — the cell line that has apparently taken over any number of others commonly used in science, suggesting that many researchers may not have been studying what they thought they were studying — is back in the news. This weekend, it was the DNA sequence of the cells that’s made headlines, with a quiet unpublishing of data.

As Rebecca Skloot, author of The Immortal Life of Henrietta Lacks — Lacks’s name is where “HeLa” comes from, as they’re her cells — wrote in the New York Times Sunday, a group of researchers at the European Molecular Biology Laboratory published an analysis of the HeLa cells’ genome on March 11 in G3: Genes, Genomes, Genetics, a new journal from the Genetics Society of America.

That genome, of course, could be very useful in research, given how widely used HeLa cells are. But the problem was Continue reading Geneticists take HeLa sequence off-line after Lacks family notes they hadn’t given consent

Seals of disapproval, as pinniped paper gets yanked for plagiarism

ImageJoseph Hoffman, an animal behavior researcher at the University of Bielefeld in Germany says he got a “kind of odd” feeling as he read a recent paper on the transcriptome of the spotted seal. Let’s just call it deja vu.

The article, “Characterization of the spotted seal Phoca largha transcriptome using Illumina paired-end sequencing and development of SSR markers,” which appeared in Comparative Biochemistry and Physiology Part D: Genomics and Proteomics:

Continue reading Seals of disapproval, as pinniped paper gets yanked for plagiarism

Paper with “missing or placed wrongly” controls retracted because there’s “no editorial mechanism to review the errors”

jgvTwo researchers from Singapore are retracting a paper that included errors in three figures because there’s apparently no way to fix the mistakes and have the new work reviewed.

Here’s the notice for “Host-dependent effects of the 3′ untranslated region of turnip crinkle virus RNA on accumulation in Hibiscus and Arabidopsis,” by Weimin Li and Sek-Man Wong of National University of Singapore and Temasek Life Sciences Laboratory: Continue reading Paper with “missing or placed wrongly” controls retracted because there’s “no editorial mechanism to review the errors”

Author retracts FASEB Journal paper for data reuse

fasebThe FASEB Journal has retracted a 2012 paper by a group from the University of Alabama, Birmingham (UAB), looking at the role of a tumor-suppressing micro-RNA in pulmonary fibrosis. The retraction suggests the provenance of the data are in question, and we learned details of what went wrong.

Here’s the notice, which, sadly, is behind a $12-per-day paywall: Continue reading Author retracts FASEB Journal paper for data reuse

“Unreliable” findings fell TB gene study in PLOS ONE

plosoneHere’s a nice example of how science should work.

A team of Swiss microbiologists has retracted their 2012 paper in PLoS One on the genetics of the TB mycobacterium after learning that the fusion protein they thought they’d used in their study was in fact a different molecule.

Here’s the retraction notice for the article, “A β-lactamase based reporter system for ESX dependent protein translocation in mycobacteria,” which has been cited once, according to Thomson Scientific’s Web of Knowledge: Continue reading “Unreliable” findings fell TB gene study in PLOS ONE

What happens when a correction is retracted?

Seyed Rasoul Mousavi, assistant professor in the department of electrical and computer engineering at the Isfahan University of Technology in Khomeynīshahr, Iran, has been working on a way to help biologists assemble genomes with as little information as possible.

Last year, Mousavi submitted a manuscript to the Journal of Theoretical Biology, received acceptance after peer review, and got proofs back to edit.

For technical reasons, Mousavi says his corrections didn’t make it into the final article published on Jan. 12, so the publishers issued a separate corrigendum with the editorial changes. Then, on Feb. 8, the publishers retracted the corrigendum that accompanied the original article. The retraction of the corrigendum reads: Continue reading What happens when a correction is retracted?

Biologists delete paper from literature after realizing they’d deleted too many genes

Researchers deleted more genes than they bargained for in a Drosophila strain, a mistake that resulted in a retraction of a paper from 2007.

Ron Wides, a biologist specializing in pattern development at Bar-Ilan University, Israel, and colleagues have retracted a paper published in Mechanisms of Development after his lab found that their technique to delete the Ten-a gene ended up deleting other nearby genes, too.

It was deletions of other genes, and not Ten-a, that killed the fruit flies, Wides concluded. His group had also concluded, erroneously, that Ten-a is what’s known as a “pair-rule” gene. Fruit fly embryos develop in stacked segments, like tubes of Pringles; pair-rule genes guide the development of alternating segments. Those other loci, and not Ten-a, caused lethality and caused the flies to develop improperly early,  Wides concluded.

The retraction reads in full: Continue reading Biologists delete paper from literature after realizing they’d deleted too many genes

A “retraction in part” for Anil Potti and colleagues, in Molecular Cancer Therapeutics

A partial retraction has joined the ten retractions and five corrections of Anil Potti’s papers, this one of a 2008 paper in Molecular Cancer Therapeutics. The move comes 14 months after the retraction of the Nature Medicine paper upon which much of the Molecular Cancer Therapeutics paper was based.

Here’s the notice: Continue reading A “retraction in part” for Anil Potti and colleagues, in Molecular Cancer Therapeutics

Errors force retraction of Blood paper on genetics of Hodgkin’s lymphoma

The authors of a paper published last September in Blood about alleged links between certain genes and Hodgkin’s lymphoma have retracted it, after realizing they’d made mistakes in their calculations.

The retraction notice for “Multiple HLA class I and II associations in classical Hodgkin lymphoma and EBV status defined subgroups,” dated January 20 and signed by all of the authors, clearly explains what went wrong, taking pains to note that there was no misconduct involved: Continue reading Errors force retraction of Blood paper on genetics of Hodgkin’s lymphoma

Sebastiani and Perls longevity genes work finds a new home in PLoS ONE following Science retraction

via Wikimedia

Today, without us having planned it, has become the day of retracted papers that found a new home.

This morning, we posted an item about a chimp “culture” paper that was retracted from Biology Letters after its authors found some errors, and then published, with corrections, in the Journal of Human Evolution. This afternoon, we bring you the news of a PLoS ONE paper on longevity genes that is the corrected version of a Science paper retracted last year: Continue reading Sebastiani and Perls longevity genes work finds a new home in PLoS ONE following Science retraction