Three more Bulfone-Paus retraction notices out, in Journal of Immunology

Silvia Bulfone-Paus

The retraction notices for papers by Silvia Bulfone-Paus continue to appear. Yesterday, the Journal of Immunology posted notices for these three previously accepted retractions by the researcher, work at whose Borstel Centre lab is under investigation for misconduct.

We wrote what? Breast cancer paper falls to rogue author

Something was fishy at China Normal University. According to the journal Anti-Cancer Drugs, a 2010 paper by researchers at the Beijing school — “3,30′-Diindolylmethane negatively regulates Cdc25A and induces a G2/M arrest by modulation of microRNA21 in human breast cancer cells” — turned out to have suffered from an unfortunate anomaly. According to the retraction notice: Continue reading We wrote what? Breast cancer paper falls to rogue author

In retraction notice, Bulfone-Paus “declares” data and conclusions confirmed; journals accept six more retractions

Silvia Bulfone-Paus

There was more news today about papers co-authored by Silvia Bulfone-Paus, whose lab at Research Centre Borstel has been under investigation for scientific misconduct.

The EMBO Journal, which we reported last month had accepted the retraction of a 2005 Bulfone-Paus paper that has been cited 37 times, published the retraction notice for the study today:

Eight of the authors (ZO, LT, UM, PB, CB, DA, RP and SB-P) wish to retract this paper, following an independent formal investigation initiated by the Research Center Borstel into scientific misconduct (see http://www.fz-borstel.de/cms/index.php?id=1). The investigation concluded that multiple figures contained PCR and western blot duplications and possible other manipulations (Figures 2A, 3A, 4A, 5, 7A and 7C, Supplementary Figures S1A, S2A and S2B, unconfirmed: Figure 1C). The above signed declare that Vadim Budagian and Elena Bulanova conducted these experiments and generated the figures. The authors declare that key experiments presented in the majority of these figures were recently reproduced and that the results confirmed the experimental data and the conclusions drawn from them. However, due to these unacceptable irregularities, the listed authors retract this paper in its entirety and regret any adverse consequences that may have resulted from its publication. Vadim Budagian and Elena Bulanova declined to sign the retraction.

As retraction notices go, this is better than average, we must say. It’s certainly better than the many opaque notices we’ve seen. But there’s a line in there that Karin Wiebauer and David Hardman, both of whom brought the notice to our attention, found curious: Continue reading In retraction notice, Bulfone-Paus “declares” data and conclusions confirmed; journals accept six more retractions

No Potti retractions on the horizon from JAMA, NEJM

With the third retraction of a paper by Anil Potti this weekend, plus details of various investigations dribbling out, we decided to check in with the world’s two leading medical journals about whether they planned to retract the papers of Potti’s they’d published.

JAMA published two papers by Potti and colleagues: One, “Gene Expression Signatures, Clinicopathological Features, and Individualized Therapy in Breast Cancer,” appeared in 2008. It has been cited 51 times, according to Thomson Scientific’s Web of Knowledge, and was the subject of two letters. In one, a correspondent expressed concerns about the lack of information in the study about Continue reading No Potti retractions on the horizon from JAMA, NEJM

Lancet Oncology retracts previously questioned Anil Potti paper

courtesy Duke

Early in December, as the house of cards that is Anil Potti‘s publication record started to really collapse, we called attention to a paper in The Lancet Oncology that had already been the subject of a correction and Expression of Concern in July of last year. Today, the journal officially retracted the paper, “Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial.” The paper was cited more than 100 times, according to Google Scholar.

The retraction notice: Continue reading Lancet Oncology retracts previously questioned Anil Potti paper

And that’s 14: More (and more) Mori retractions, as Japanese cancer journal pulls three papers

Naoki Mori

The steady drip-drip-dripping sound you hear from the cancer literature these days comes from the stream of retractions involving studies by Naoki Mori, the now jobless scientist whose work on cancer viruses appears to be evaporating before our eyes.

Cancer Science, which used to be called the Japanese Journal of Cancer Research,  has retracted three more of Mori’s papers, each of which, according to the journal, contained multiple unreliable images. That brings the tally of retractions involving Mori’s articles to 14 by our count, an impressive number by any measure. Mori has more than 50 papers to his name, however, so it’s possible that the number of retractions will grow.

Here are the latest retractions: Continue reading And that’s 14: More (and more) Mori retractions, as Japanese cancer journal pulls three papers

Clinical Infectious Diseases retracts antibiotic guidelines after posting uncorrected version

A few days after Clinical Infectious Diseases published a set of guidelines for using antibiotics in patients with cancer and dangerously compromised immune systems, we noticed that they had retracted the paper. The Medline notice read: Continue reading Clinical Infectious Diseases retracts antibiotic guidelines after posting uncorrected version

Sixth Bulfone-Paus retraction accepted

Silvia Bulfone-Paus

A journal has accepted the sixth retraction of a paper co-authored by Silvia Bulfone-Paus, the Research Centre Borstel announced late last week. Borstel has been investigating allegations that two of Bulfone-Paus’s former postdocs manipulated images.

The paper, in the Scandinavian Journal of Immunology, is titled Continue reading Sixth Bulfone-Paus retraction accepted

Cracking the Mori case: A reviewer describes how manipulated images came to light

Naoki Mori

We’ve had two questions since learning of the fraud case involving Naoki Mori: Who discovered the manipulations? And how?

We now have answers. We recently received an e-mail from a researcher who specializes in Mori’s field — cancer viruses — and who claims to have been a reviewer of a paper he submitted early last year to a journal in his field. (We’re obscuring some details to maintain our source’s anonymity.)

During what turned out to be a “painful” review of the manuscript: Continue reading Cracking the Mori case: A reviewer describes how manipulated images came to light

Resurrection? Paper about Jesus and the flu remains online, not marked as retracted

In August, we reported on the retraction of a paper in Virology Journal about whether a woman allegedly cured by Jesus Christ had the flu or some other ailment. The original paper was published on July 21, 2010. On August 11, after a flurry of criticism from various bloggers, the journal’s editor, Robert Garry, apologized for publishing it in a comment. On the 13th, the journal published a retraction notice.

But as an eagle-eyed Retraction Watch reader has pointed out, the original paper, and its abstract, both remain online, without any suggestion that the paper was retracted. We found that puzzling, so we called Garry, of Tulane’s department of microbiology and immunology. Continue reading Resurrection? Paper about Jesus and the flu remains online, not marked as retracted