More HeLa problems: For decades, a widely used bladder cancer line hasn’t been what scientists thought

jurolAbout a year ago, we wrote about the retraction of a paper in Oral Oncology that highlighted a big issue in oncology research: Widespread contamination of cancer cell lines by other lines, making findings difficult to interpret.

One of the common contaminants is HeLa cells. HeLa, of course, stands for Henrietta Lacks, the subject of Rebecca Skloot’s bestseller The Immortal Life of Henrietta Lacks. As we noted last year, Continue reading More HeLa problems: For decades, a widely used bladder cancer line hasn’t been what scientists thought

Retraction count for gynecologic cancer researcher Takai grows to seven

cancerlettersNoriyuki Takai, a gynecologic cancer researcher at Oita University in Japan who retracted three papers last October, has four more retractions, these in Cancer Letters.

All but one of the notices reads as follows: Continue reading Retraction count for gynecologic cancer researcher Takai grows to seven

“Highly unethical practices” force four retractions for nanotech researcher

acta biomaterialiaSanjeeb K. Sahoo, of the Institute of Life Sciences in Bhubaneswar, India, has had four papers retracted from Acta Biomaterialia for what the journal is calling “highly unethical practices.”

All four notices say the same thing: Continue reading “Highly unethical practices” force four retractions for nanotech researcher

Lifted figure prompts retraction of Oncogene paper by Roman-Gomez

onc_cimageThe journal Oncogene has retracted a 2005 paper from a group led by Jose Roman-Gomez, a Spanish researcher who appears to be a serial image manipulator/misappropriator.

The article, “Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia,” was published online in September 2005 and has been cited 106 times, according to Thomson Scientific’s Web of Knowledge.

Now comes this: Continue reading Lifted figure prompts retraction of Oncogene paper by Roman-Gomez

Correction for MD Anderson’s Aggarwal, cancer researcher whose work is under investigation

jmm113coverBharat Aggarwal, the highly cited MD Anderson Cancer Center researcher who has confirmed to us that his work is under investigation by the institution, has a correction of his work in the Journal of Molecular Medicine. Troubled images are to blame — as they have been in previous retractions, and at least one other correction, of Aggarwal’s papers.

The paper, “Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor,” was published in December 2010 and cited 15 times since, according to Thomson Scientific’s Web of Knowledge.

Here’s the notice: Continue reading Correction for MD Anderson’s Aggarwal, cancer researcher whose work is under investigation

Leading cancer researcher retracts 2003 paper for “inappropriate presentation”

cancer cellOne of the world’s leading cancer researchers, MIT’s Robert Weinberg, has retracted a decade-old paper after finding out it contained errors.

Here’s the notice for “Ras Modulates Myc Activity to Repress Thrombospondin-1 Expression and Increase Tumor Angiogenesis,” a paper originally published in Cancer Cell in 2003: Continue reading Leading cancer researcher retracts 2003 paper for “inappropriate presentation”

“Extensive” errors force retraction of lymphoma radiation paper

IJROBPcoverA group of researchers from Mexico has been forced to retract their July 2012 paper in the International Journal of Radiation Oncology *Biology*Physics after a reader noticed cracks in the data that proved to be signs of fatal instability.

Here’s the retraction notice for the article, titled, “Randomized Clinical Trial to Assess the Efficacy of Radiotherapy in Primary Mediastinal Large B-Lymphoma”: Continue reading “Extensive” errors force retraction of lymphoma radiation paper

Retractions three and four for Hopkins cancer biomarker group

ccrA group of cancer researchers formerly centered at Johns Hopkins have retracted two more studies. The previous two retracted papers — one of which was the focus of a lawsuit — were about prostate cancer, while the new retractions are of papers about colon cancer.

Here’s the notice for one paper: Continue reading Retractions three and four for Hopkins cancer biomarker group

Another retraction for Pfizer’s experimental cancer treatment figitumumab

6794 BJC_newblue_V1.qxdLast month, we brought you news that Pfizer had retracted a paper in the Journal of Clinical Oncology

purporting to show a benefit of their experimental drug for lung cancer figitumumab after discovering that its clinical lead on the project had done analyses improperly.

There’s been another retraction, of a related paper, in the British Journal of Cancer, “Pre-treatment levels of circulating free IGF-1 identify NSCLC patients who derive clinical benefit from figitumumab.” Here’s the notice: Continue reading Another retraction for Pfizer’s experimental cancer treatment figitumumab

Serial plagiarists earn lifetime publishing ban from Saudi journal

saudimedicineIn April, we wrote about a group of cancer researchers from Tunisia:

The M.O. of the group…appears to be quite simple: Find a study that looks easy to “replicate,” change a few of the particulars and submit as if it were a piece of local, original work.

One of the papers we cited in that post for appearing to be heavily plagiarized has now been retracted, with a heavy penalty for the authors. Here’s the notice, from the Annals of Saudi MedicineContinue reading Serial plagiarists earn lifetime publishing ban from Saudi journal