Category: basic life sciences retractions

A misconduct probe — which led to 20 retraction requests — took four years. Why?

Santosh Katiyar

A probe into the work of a researcher who studied natural products for cancer had many stops and starts along the way — including five extensions granted by the U.S. Office of Research Integrity — according to documents obtained by Retraction Watch.

Following a public records request, we recently obtained a copy of the report on the investigation of allegations of misconduct by Santosh Katiyar, issued jointly by the University of Alabama Birmingham and the Birmingham VA Medical Center. As a result of the report, the institutions have requested 20 retractions of work by Santosh Katiyar, who received millions in funding from the U.S. National Institutes of Health. 

How does the report stack up?

Continue reading A misconduct probe — which led to 20 retraction requests — took four years. Why?

Misconduct probe of once rising star prompts retraction of cat’s meow paper

A group of Australian researchers who studied the cat’s meow as a model for urinary incontinence and other motor-neural issues in people have lost a 2015 paper in the wake of a misconduct investigation.

The target of the inquiry was Hari Subramanian, a former senior research fellow at the Queensland Brain Institute, part of the University of Queensland (UQ). Subramanian was leading studies of incontinence in the elderly, for which he sometimes used nerve stimulators on live rodents and cats. As The Australian reported last September, animal rights activists have objected to his research methods — which sometimes involved sticking probes into the brains of living animals.  

Recently, the school launched an investigation — prompted by an unknown complainant — into the integrity of Subramanian’s data in two articles, including one, now retracted, that appeared in the Journal of Comparative Neurology.  

The case is controversial, to say the least, replete with allegations of unfair attacks. Subramanian’s lawyer told us the journal may be reviewing its decision to retract the paper. (We couldn’t confirm that with the editor.)

Here’s what we’ve found out so far.

Continue reading Misconduct probe of once rising star prompts retraction of cat’s meow paper

How much cancer stems from diabetes, obesity? Lancet journal swaps high-profile paper

Six months ago, the media was ablaze with the findings of a new paper, showing that nearly six percent of cancer cases are caused, at least in part, by obesity and diabetes. But this week, the journal retracted that paper — and replaced it with a revised version.

The new paper doesn’t change the main findings much — the share of all cancers attributable to diabetes and obesity changed from 5.6% to 5.7%, which wouldn’t change any headlines about the original paper. But soon after the paper was published, a group of researchers noticed the authors’ mistake — which was significant enough to prompt the journal to retract the paper entirely, and swap it with a new one.

According to first author Jonathan Pearson-Stuttard at Imperial College London:

Continue reading How much cancer stems from diabetes, obesity? Lancet journal swaps high-profile paper

Two years after student loses PhD, ORI concludes he committed misconduct

The U.S. Office of Research Integrity (ORI) announced today that a former graduate student committed research misconduct — nearly two years after his institution stripped him of his degree.

The ORI concluded that Shiladitya Sen committed misconduct in a PNAS paper (retracted six months ago), his PhD thesis, a poster presentation, and two grant applications to the National Institutes of Health (NIH). Sen has agreed not to seek federal funding for three years.

A spokesperson for The Ohio State University (OSU), where Sen was based, told us its investigation wrapped up in Spring 2016, and Sen’s PhD was revoked that June. It’s not clear why it took two years for the ORI to issue its own finding; the ORI did not immediately respond to requests for comment.

According to ORI’s notice, Sen:

Continue reading Two years after student loses PhD, ORI concludes he committed misconduct

Caught Our Notice: A team from Harvard, Cornell, Cambridge, HHMI, and UCSF can’t reproduce a paper’s findings

What Caught Our Attention: Any time there’s an issue with a paper co-authored by researchers from such high-profile institutions as Harvard, Cornell, and the University of Cambridge, we take notice. In this case, the group — which included Laurie Glimcher, then-dean at Cornell, now president of the Dana-Farber Cancer Institute — chose to retract a 2013 paper from a Cell journal after learning they couldn’t reproduce some of the experiments. Continue reading Caught Our Notice: A team from Harvard, Cornell, Cambridge, HHMI, and UCSF can’t reproduce a paper’s findings

Caught Our Notice: Hey peer reviewers — did you even read this paper??

What Caught Our Attention: A tree of life paper has been axed — and based on the information in the retraction notice, we’re wondering how it ever passed peer review.

Specifically, the notice states a review of the paper found “concerns regarding the study design, methodology, and interpretation of the data.” Overall, the research “contradict(s) a large body of existing literature and do(es) not provide a sufficient level of evidence to support the claims made in the paper.” Um, so what did it get right?

Continue reading Caught Our Notice: Hey peer reviewers — did you even read this paper??

A cancer researcher said she collected blood from 98 people. It was all her own.

A researcher collected her own blood and forged the labels so it would appear to be samples from nearly 100 people, according to a new finding of research misconduct released today by the U.S. Office of Research Integrity (ORI).

The former researcher at the University of Texas MD Anderson Cancer Center swapped her own blood samples for those taken from 98 human subjects. The misconduct affects two grant progress reports and two papers; one paper has already been retracted, and the former “research interviewer” — Maria Cristina Miron Elqutub — has agreed to correct or retract the other.

Adel El-Naggar, a co-author on both of the papers also based at the University of Texas MD Anderson Cancer Center, told Retraction Watch:

Continue reading A cancer researcher said she collected blood from 98 people. It was all her own.

Mount Sinai multiple sclerosis researcher admits to misconduct

Gareth John

A researcher who has received millions in funding from the U.S. National Institutes of Health and who runs a lab at the Icahn School of Medicine at Mount Sinai in New York has confessed to falsifying data in a 2014 paper.

Gareth John, who studies multiple sclerosis and other neurological diseases, “has expressed remorse for his actions,” according to a report released last week from the U.S. Department of Health and Human Services’ Office of Research Integrity. Continue reading Mount Sinai multiple sclerosis researcher admits to misconduct

Researcher loses battle with Cell over wording of retraction notice

For months, a researcher has wrestled with a journal over the wording of an upcoming retraction notice. It appears that she has lost.

Earlier this week, Cell retracted the paper, despite the protests of first author Shalon Babbitt Ledbetter. When Ledbetter learned the journal was planning to retract the biochemistry paper over image manipulations, but wouldn’t name the culprit in the notice, she shared her concerns on PubPeer. Although a 2015 letter sent to Cell from Saint Louis University identified last author Dorota Skowyra as responsible for multiple manipulations, the journal wasn’t planning to say Skowyra was responsible in the retraction notice. Which would leave all other authors — particularly Ledbetter — under a cloud of suspicion.

Now, Cell Press has finally retracted the paper, along with another paper in Molecular Cell that lists Skowyra as corresponding author. Both notices describe image manipulations that were investigated by Saint Louis University (SLU). Neither identifies who is responsible.

Continue reading Researcher loses battle with Cell over wording of retraction notice

Authors retract heart disease paper for “nonscientific reason”

Researchers have retracted a 2018 paper about the genetic underpinnings of heart disease from the FASEB Journal — and it’s not entirely clear why.

The paywalled retraction notice simply cites a “nonscientific reason.” Cody Mooneyhan, the director of publications at the journal, declined to provide further details, and the authors have provided different accounts of what happened: The paper’s corresponding author, John Yu, told Retraction Watch that he requested the retraction because the first author, Chia‐Ti Tsai, refused to sign the journal’s copyright agreement. Tsai, a professor in the Department of Internal Medicine at National Taiwan University in Taipei, told us he was “not notified before the paper was submitted.” Continue reading Authors retract heart disease paper for “nonscientific reason”