Microbial reproduction: Plagiarism from Wikipedia, elsewhere leads to retraction of biotech paper

When is an advance not an advance?

Biotechnology Advances has retracted a 2008 review by researchers in India who allegedly stole chunks of their manuscript from several sources including journal articles, Wikipedia, and StateMaster.com, a statistics clearinghouse.

According to the notice, the article, titled “Microbial production of dihydroxyacetone” Continue reading Microbial reproduction: Plagiarism from Wikipedia, elsewhere leads to retraction of biotech paper

2009 Cell paper on muscular dystrophy gene link retracted

A Cell paper reporting on genetic mutations responsible for a form of muscular dystrophy was retracted earlier this month. According to the retraction:

Our paper reported the identification of mutations in the gene VMA21 in patients with X-linked myopathy with excessive autophagy (XMEA) and characterized the molecular mechanisms underlying the disease phenotype. Many of the figure panels in the paper summarize data from multiple experiments. We have now detected a number of errors in these panels. Although we stand by the validity of our conclusions, we believe that the most responsible course of action is to retract our paper. We are preparing an expanded version of our work for future submission. We deeply regret this circumstance and apologize to the community.

One of the original authors, Dr. Aubourg, could not be reached regarding this Retraction.

The study has been cited 11 times, according to Thomson Scientific’s Web of Knowledge. Here’s a press release the researchers’ hospital, Sick Kid’s of Toronto, sent out when it was originally published.

Best Of Retractions Part II: Keyword search “Irony” as paper on Google infringement case plagiarized

For would-be plagiarists, now is both the best and worst of times. Thanks to Google and other search tools, never has it been easier to appropriate someone else’s thoughts or words. But the Internet taketh away, too—offering up scads of sleuthing software that promise the ability to sniff out cheats.

Which is what makes this post about a retraction in Computer Law & Security Review all the more delicious. As they say in the law, res ipsa loquitur: Continue reading Best Of Retractions Part II: Keyword search “Irony” as paper on Google infringement case plagiarized

Gene therapy researcher Savio Woo retracts two more papers

courtesy Mount Sinai School of Medicine

Mount Sinai School of Medicine researcher Savio Woo, whom Retraction Watch reported last week has already retracted four papers from major journals as two postdocs have been fired from his lab, has retracted two more from Molecular Therapy: The Journal of the American Society of Gene Therapy.

The two papers, both from 2007, were Continue reading Gene therapy researcher Savio Woo retracts two more papers

Best Of Retractions, Part I: Water, water, everywhere, except in “Historical Palestine,” aka Israel

Although Retraction Watch might have been born just before yesterday, we find it instructive to look back in time for items we would have covered had we been around a bit longer. We’ll do this periodically to generate a “Best Of” collection of retractions that catch our eye both for what they might suggest about scientific publishing and for good old-fashioned  interest. Here’s the first installment:

A furtive attempt to play politics with a galley proof led to the retraction of a paper on Middle East water policy a few months ago. The article, “Optimizing irrigation water use in the West Bank, Palestine,” appeared in the February 2010 issue of Agricultural Water Management, an Elsevier journal. Written by Palestinian and Dutch researchers, the article modeled various scenarios of water and crop policies in the West Bank in an effort to determine the most efficient use of resources.

But a funny thing happened on the way to the printer. The authors decided to make a political protest of sorts in the galleys, a ham-handed gesture that led to the retraction of the paper, as the journal explained in a note: Continue reading Best Of Retractions, Part I: Water, water, everywhere, except in “Historical Palestine,” aka Israel

Update on gene therapy researcher Savio Woo retractions: Two post-docs dismissed for fraud

More on the case of Savio Woo, the New York gene therapy researcher who, as Retraction Watch reported  this week, had several papers pulled by noted journals.

Two of Woo’s post-doctoral fellows at Mount Sinai School of Medicine were dismissed for “research misconduct,” said Ian Michaels, a spokesman for the institution. According to Michaels:

When Dr. Savio L C Woo came to suspect that two post-doctoral fellows in his laboratory may have engaged in research misconduct he notified the Mount Sinai Research Integrity Office. Mount Sinai immediately initiated institutional reviews that resulted in both post-doctoral fellows being dismissed for research misconduct. At no time were there allegations that Dr. Woo had engaged in research misconduct. As part of its review, the investigation committee looked into this possibility and confirmed that no research misconduct could be attributed to Dr. Woo, who voluntarily retracted the papers regarding the research in question. Mount Sinai reported the results of its investigations to the appropriate government agencies and continues to cooperate with them as part of its commitment to adhere to the highest standards for research integrity.

We have plenty of other questions for Mount Sinai about the details of the investigation—including when the post-docs were let go, which Michaels declined to answer—and will update when we learn more.

Work from noted gene therapy researcher Savio Woo under scrutiny with slew of retractions

Research from the lab of Savio Woo, a leading U.S. gene therapy scientist, has come into question with the retraction by major journals of at least four of his articles.

The papers, which appeared in the Proceedings of the National Academy of Sciences, the Journal of the National Cancer Institute and Human Gene Therapy, involve findings published between 2005 and 2009, address various aspect of gene therapy. Two of the articles boasted of potential breakthroughs, and even a possible cure, for diseases with extremely high rates of mortality.

The study in JNCI, for example, reported the finding of a genetically modified bacterium that showed promise for the treatment of pancreatic cancer, a particularly lethal malignancy, and other tumor types. Another, published in 2005 in PNAS, claimed to have discovered a possible cure for phenylketonuria, or PKU, in mice—a finding that was cited more than 30 times and trumpeted in the media.

However, in a retraction notice issued this month, Woo wrote that: Continue reading Work from noted gene therapy researcher Savio Woo under scrutiny with slew of retractions

What happens after a retraction for falsified data? An example from Endocrinology

In the world of scientific misconduct, it’s often worth keeping track of what happens to scientists whose papers were retracted because of falsified or otherwise fraudulent results.

Take the case of Hung-Shu Chang. Last week, the the federal Office of Research Integrity announced that it had closed its investigation into the scientist’s misdeeds. Chang was a visiting postdoctoral researcher from Taiwan who in 2005 had come to the renowned Skinner Laboratory at Washington State University to study the effects of endocrine disruptors — a class of compounds that includes BPA and which have been shown to disrupt the action of hormones — on sex cells.

Chang was accused of falsifying data in a 2006 paper in Endocrinology — later retracted — reporting the damaging effects of vinclozolin, a fungicide used to protect vineyards, on the genetic integrity of sperm cells.

According to federal and university investigators, Chang, who has since returned to Taiwan, “fabricated and falsified data” central to the authors’ claim that vinclozolin could alter sperm in such a way that the mutations could cause disease in future generations. Such mutations are referred to as epigenetic changes. Continue reading What happens after a retraction for falsified data? An example from Endocrinology

Update on stem cell-cancer link retraction: Why not everyone signed, and why authors ended up in another journal first

Last month, we wrote about the retraction of a 2005 paper suggesting that some adult stem cells might give rise to cancer. That, of course, would be a problem if researchers tried treating heart disease and other conditions with them. The paper’s authors retracted it, however, when it became clear that instead of being transformed — that’s the scientific word for “became cancerous” — the cells had simply become contaminated and overgrown with tumor cells used in research.

We had some questions for the authors of the original paper, and for the editor of the journal. Last week, we heard back from one of the paper’s authors, Javier Garcia-Castro, who had been on vacation without Internet access for weeks. In an email to Retraction Watch, Garcia-Castro wrote: Continue reading Update on stem cell-cancer link retraction: Why not everyone signed, and why authors ended up in another journal first

Missing authors: Journal retracts article showing stinky dairy products make good mosquito bait

Citing “authorship” issues, a parasitology journal has retracted a paper by a Kenyan scientist which showed that Limburger cheese and milk cream may be effective mosquito bait.

The paper, by Eunice Owino, of the University of Nairobi, was published online in Parasites & Vectors this June but retracted in late August after the editors quickly learned that Owino had neglected to list several other authors on her manuscript.

According to Chris Arme, a parasitologist and editor-in-chief of the journal, the article began to smell like Lim … well, you know, immediately: Continue reading Missing authors: Journal retracts article showing stinky dairy products make good mosquito bait